4.6 Review

The Membrane Interaction of Alpha-Synuclein

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

Debasis Das et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

Ersoy Cholak et al.

FASEB JOURNAL (2020)

Article Biochemistry & Molecular Biology

α-Synuclein facilitates endocytosis by elevating the steady-state levels of phosphatidylinositol 4,5-bisphosphate

Meir Schechter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2020)

Article Neurosciences

Alpha-Synuclein Continues to Enhance SNARE-Dependent Vesicle Docking at Exorbitant Concentrations

Brenden J. D. Hawk et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

Synapsins regulate α-synuclein functions

Merav Atias et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling

Jichao Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Editorial Material Biochemistry & Molecular Biology

Synaptic vesicle fusion: today and beyond

Nils Brose et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Interplay between α-synuclein amyloid formation and membrane structure

Emma O'Leary et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2019)

Review Biochemistry & Molecular Biology

Biochemical studies of membrane fusion at the single-particle level

Zhiqi Tian et al.

PROGRESS IN LIPID RESEARCH (2019)

Article Neurosciences

α-Synuclein promotes dilation of the exocytotic fusion pore

Todd Logan et al.

NATURE NEUROSCIENCE (2017)

Article Biochemistry & Molecular Biology

α-Synuclein may cross-bridge v-SNARE and acidic phospholipids to facilitate SNARE-dependent vesicle docking

Xiaochu Lou et al.

BIOCHEMICAL JOURNAL (2017)

Article Cell Biology

Ca2+ is a key factor in α-synuclein-induced neurotoxicity

Plamena R. Angelova et al.

JOURNAL OF CELL SCIENCE (2016)

Review Cell Biology

SNARE-mediated membrane fusion in autophagy

Yongyao Wang et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)

Review Neurosciences

Versatile Structures of α-Synuclein

Chuchu Wang et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2016)

Correction Biochemistry & Molecular Biology

Dopamine transporter activity is modulated by α-synuclein

Brittany Butler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Neurosciences

Definition of a Molecular Pathway Mediating α-Synuclein Neurotoxicity

Jacqueline Burre et al.

JOURNAL OF NEUROSCIENCE (2015)

Review Biochemistry & Molecular Biology

Towards reconstitution of membrane fusion mediated by SNAREs and other synaptic proteins

Axel T. Brunger et al.

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Nonaggregated α-Synuclein Influences SNARE-Dependent Vesicle Docking via Membrane Binding

Ying Lai et al.

BIOCHEMISTRY (2014)

Article Biochemistry & Molecular Biology

α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling

Lina Wang et al.

CURRENT BIOLOGY (2014)

Article Multidisciplinary Sciences

α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation

Jacqueline Burre et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour

Giuliana Fusco et al.

NATURE COMMUNICATIONS (2014)

Article Medicine, Research & Experimental

Alpha-Synuclein Function and Dysfunction on Cellular Membranes

David Snead et al.

Experimental Neurobiology (2014)

Article Clinical Neurology

G51D α-Synuclein mutation causes a novel Parkinsonian-pyramidal syndrome

Suzanne Lesage et al.

ANNALS OF NEUROLOGY (2013)

Review Physiology

Perspectives on Kiss-and-Run: Role in Exocytosis, Endocytosis, and Neurotransmission

AbdulRasheed A. Alabi et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 75 (2013)

Article Clinical Neurology

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

Silke Appel-Cresswell et al.

MOVEMENT DISORDERS (2013)

Review Neurosciences

The many faces of alpha-synuclein: from structure and toxicity to therapeutic target

Hilal A. Lashuel et al.

NATURE REVIEWS NEUROSCIENCE (2013)

Editorial Material Clinical Neurology

A NOVEL α-SYNUCLEIN MISSENSE MUTATION IN PARKINSON DISEASE

Christos Proukakis et al.

NEUROLOGY (2013)

Review Neurosciences

The Function of α-Synuclein

Jacob T. Bendor et al.

NEURON (2013)

Article Multidisciplinary Sciences

Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking

Bong-Kyu Choi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open

Lei Shi et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

α-Synuclein Stimulates a Dopamine Transporter-dependent Chloride Current and Modulates the Activity of the Transporter

Jarod Swant et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Membrane Curvature Sensing by Amphipathic Helices A SINGLE LIPOSOME STUDY USING α-SYNUCLEIN AND ANNEXIN B12

Martin Borch Jensen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Chemistry, Multidisciplinary

Allostery in a Disordered Protein: Oxidative Modifications to α-Synuclein Act Distally To Regulate Membrane Binding

Eva Sevcsik et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Biochemistry & Molecular Biology

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1

Frits Kamp et al.

EMBO JOURNAL (2010)

Article Multidisciplinary Sciences

α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

Jacqueline Burre et al.

SCIENCE (2010)

Article Biochemistry & Molecular Biology

Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants MOLECULAR SIMULATIONS OF THE MICELLE- AND BILAYER-BOUND FORMS

Jason D. Perlmutter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Biochemistry & Molecular Biology

Membrane fusion

William Wickner et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Article Cell Biology

Inhibition of vesicular monoamine transporter-2 activity in alpha-synuclein stably transfected SH-SY5Y cells

Jun Tang Guo et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2008)

Review Biochemistry & Molecular Biology

Neuropathology, biochemistry, and biophysics of α-synuclein aggregation

Vladimir N. Uversky

JOURNAL OF NEUROCHEMISTRY (2007)

Review Biochemistry & Molecular Biology

Interactions between metals and α-synuclein -: function or artefact?

David R. Brown

FEBS JOURNAL (2007)

Article Biochemistry & Molecular Biology

Helix periodicity, topology, and dynamics of membrane-associated α-Synuclein

R Bussell et al.

PROTEIN SCIENCE (2005)

Article Clinical Neurology

The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia

JJ Zarranz et al.

ANNALS OF NEUROLOGY (2004)

Article Multidisciplinary Sciences

Double-knockout mice for α- and β-synucleins:: Effect on synaptic functions

S Chandra et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

α-synuclein has a high affinity for packing defects in a bilayer membrane -: A thermodynamics study

B Nuscher et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

NMR of α-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation

CO Fernández et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins

R Bussell et al.

JOURNAL OF MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

A broken α-helix in folded α-synuclein

S Chandra et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Neurosciences

Attenuation of dopamine transporter activity by α-synuclein

C Wersinger et al.

NEUROSCIENCE LETTERS (2003)

Article Biochemistry & Molecular Biology

α-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

HA Lashuel et al.

JOURNAL OF MOLECULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

Distinct roles of the N-terminal-binding domain and the C-terminal-solubilizing domain of α-synuclein, a molecular chaperone

SM Park et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Ca2+ binding to α-synuclein regulates ligand binding and oligomerization

MS Nielsen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Biochemistry & Molecular Biology

Conformational properties of α-synuclein in its free and lipid-associated states

D Eliezer et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)