Journal
BIOFABRICATION
Volume 13, Issue 3, Pages -Publisher
IOP PUBLISHING LTD
DOI: 10.1088/1758-5090/abec2c
Keywords
additive manufacturing; 3D bioprinting; bioinks; biomaterials; hydrogels
Funding
- project B-Fabulus 'BiofabricacAo de estruturas 3D funcionalizadas para regeneracAo meniscal personalizada' - Portuguese Foundation for Science and Technology (FCT) [PTDC/BBB-ECT/2690/2014]
- project 3BioMeD - Portuguese Foundation for Science and Technology (FCT) [JICAM/0001/2017]
- COMPETE 2020
- Fundo Europeu de Desenvolvimento Regional (FEDER) through the Program Interreg V-A Espana-Portugal (POCTEP) 2014-2020 [0624_2IQBIONEURO_6]
- FCT [IF/00115/2015, IF/01285/2015]
- Fundação para a Ciência e a Tecnologia [JICAM/0001/2017, PTDC/BBB-ECT/2690/2014] Funding Source: FCT
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Three-dimensional (3D) bioprinting technology has gained significant attention in biomedical engineering and clinical applications, with advancements in bioink development allowing for more precise mimicry of native tissue characteristics and support for biofunctionality.
In recent years, three-dimensional (3D) bioprinting has attracted wide research interest in biomedical engineering and clinical applications. This technology allows for unparalleled architecture control, adaptability and repeatability that can overcome the limits of conventional biofabrication techniques. Along with the emergence of a variety of 3D bioprinting methods, bioinks have also come a long way. From their first developments to support bioprinting requirements, they are now engineered to specific injury sites requirements to mimic native tissue characteristics and to support biofunctionality. Current strategies involve the use of bioinks loaded with cells and biomolecules of interest, without altering their functions, to deliver in situ the elements required to enhance healing/regeneration. The current research and trends in bioink development for 3D bioprinting purposes is overviewed herein.
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