Journal
VIROLOGY
Volume 554, Issue -, Pages 37-41Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.virol.2020.12.002
Keywords
HEV; Genotype 1; Acute infection; Semen; Sperm quality; Male infertility
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Funding
- grant office of the Faculty of Medicine, Assiut University, Egypt [2018-07-17-001, 006-27-07-2020]
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This study found no significant association between HEV infection and the male reproductive system, with HEV detectable in urine but not in semen. AHE patients did not show notable abnormalities in semen analysis, and there was no significant difference in reproductive hormone levels and semen quality between AHE patients and healthy controls.
Extrahepatic disorders are recorded with hepatitis E virus (HEV) infection. The impact of HEV infection on the male reproductive system is a query. In this study, we retrospectively analyzed semen from infertile men and prospectively examined the semen from acute hepatitis E patients (AHE) for HEV markers. HEV RNA and HEV Ag were not detectable in the semen of infertile men nor the semen of AHE patients. Although HEV markers were detectable in the urine of patients infected with HEV-1, these markers were absent in their semen. There is no significant difference in the level of reproductive hormones between AHE patients and healthy controls. Semen analysis of AHE patients did not show a notable abnormality and there was no significant difference in the semen quality and sperm characteristics between AHE and healthy controls.
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