ULTRASOUND-BASED CAROTID PLAQUE CHARACTERISTICS HELP PREDICT NEW CEREBRAL ISCHEMIC LESIONS AFTER ENDARTERECTOMY

The aim of this study was to identify the ultrasound-based carotid plaque characteristics associated with new cerebral ischemic lesions after carotid endarterectomy (CEA). Between January 2013 and December 2018, carotid duplex ultrasound was performed in 1061 patients who underwent CEA. Brain magnetic resonance diffusion-weighted imaging (DWI) was performed pre-operatively and within 30 d after CEA. New cerebral ischemic lesions on DWI were observed in 169 patients. The cutoff value gray-scale median (GSM) used to distinguish DWI-positive from DWI-negative patients was 30.5, with an area under the receiver operating characteristic curve of 0.837. A larger proportion of multiple DWI lesions were observed in the GSM <= 30.5 group (59.5% vs. 41.5%, p = 0.030). Univariate and multivariate analyses identified GSM <= 30.5, ulcerated carotid plaques and pre-operative ischemic symptoms as predictors of post-operative cerebral DWI lesions. Our results indicate that ultrasound-based carotid plaque characteristics help predict new cerebral ischemic lesions after CEA. (E-mail: dryanghua99@163.com) (C) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Automated summary

Through a study of 1061 patients undergoing CEA, it was found that GSM <= 30.5, ulcerated carotid plaques, and pre-operative ischemic symptoms were predictors of post-operative cerebral DWI lesions.