Update of the concept of type 5 resistant starch (RS5): Self-assembled starch V-type complexes

Background: All starch fractions not digested and absorbed in the small intestine of healthy humans are considered resistant starch (RS), and their habitual intake has been associated with different beneficial effects on health. In particular, starch-lipid V-type complexes, such as starch-fatty acids and starch-monoglycerides, have traditionally been classified as type 5 RS. Scope and approach: Other starch V-type complexes have emerged more recently, such as starch-glycerol, starch-amino acids, starch-peptides, starch-proteins, starch-lipid-protein, starch-polyphenols, starch-other polysaccharides, among others, which do not fit well into the traditionally accepted nutritional classification of RS. Here, these complexes are analyzed in order to highlight the pertinence of redefining RS5 for the inclusion of this new type of RS. Key findings and conclusions: All those self-assembled starch V-type complexes can be classified as RS5. However, starch-polyphenol V-type complexes should particularly be further investigated to ensure their inclusion in this new extended RS5.

Automated summary

This study discusses the concept of resistant starch (RS) in relation to starch fractions not digested and absorbed in the small intestine of healthy humans. It suggests redefining RS5 to include various new types of RS, with a particular emphasis on further investigating starch-polyphenol complexes. All self-assembled starch V-type complexes can be classified as RS5, highlighting the importance of including a wide range of complex carbohydrates in the extended RS5 classification.