Journal
TETRAHEDRON
Volume 84, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2021.132019
Keywords
Diazo compounds; Organoboranes; Metal carbenes; Copper-catalysis; B-H bond Insertion
Categories
Funding
- NSFC [21772169, 21632003]
Ask authors/readers for more resources
A facile and efficient copper(I)-catalyzed protocol for the synthesis of 4-boraneyl-1,4-dihydroisoquinolin-3-ones via B-H insertion of copper carbenes has been reported. The reactions exhibit a good scope for the substrate, mild reaction conditions, and high yields, with the products isolated as bench-stable Lewis adducts with Me3N.
A facile and efficient copper(I)-catalyzed protocol for the synthesis of 4-boraneyl-1,4-dihydroisoquinolin-3-ones via B-H insertion of copper carbenes derived from 4-diazoisoquinolin-3-ones into amine-borane Lewis adduct is reported. The reactions feature a good scope for the 4-diazoisoquinolin-3-ones, mild reaction conditions and high yields. The products are isolated as bench-stable Lewis adducts with Me3N. (c) 2021 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
