Journal
SYNTHESIS-STUTTGART
Volume 53, Issue 14, Pages 2381-2394Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/a-1401-2716
Keywords
pyridone; cytochalasan; sorbicillinoid; decalin; alpha-pyrone; meroterpenoid; tropolone sesquiterpenoid
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Funding
- DFG in Germany
- EPSRC in the UK
- BBSRC in the UK
- DFG [CO 1328/5-1]
- Leibniz Universitat Hannover
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This article discusses the advantages, disadvantages, and future opportunities of total biosynthesis in fungi, focusing on several recent examples such as 2-pyridones, cytochalasans, and sorbicillinoids.
Total biosynthesis in fungi is beginning to compete with traditional chemical total synthesis campaigns. Herein, the advantages, disadvantages and future opportunities are discussed within the scope of several recent examples. 1 Introduction 2 Synthetic Examples 2.1 2-Pyridones 2.2 Cytochalasans 2.3 Sorbicillinoids 2.4 Decalins: Solanapyrone 2.5 alpha-Pyrone Polyenes: Citreoviridin and Aurovertin 2.6 Anditomin and Related Meroterpenoids 2.7 Tropolone Sesquiterpenoids 3 Conclusion
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