Journal
SYNLETT
Volume 32, Issue 10, Pages 1019-1023Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/a-1423-5679
Keywords
diamines; aminobenzylamines; sulfinamides; Grignard reagents; stereoselectivity
Categories
Funding
- National Natural Science Foundation of China [22001093]
- Fundamental Research Funds for the Central Universities [21620354]
Ask authors/readers for more resources
This study presents a highly efficient method for the addition of Grignard reagents to N-[(o-aminophenyl)methylene]sulfinamides to produce a range of o-aminosulfinylimines with good to excellent diastereoselectivities.
Chiral o-aminobenzylamines are synthons for many chiral ligands and catalysts that have been widely used in asymmetric synthesis. Here, we report a highly efficient and stereoselective addition of Grignard reagents to N-[(o-aminophenyl)methylene]sulfinamides to give a range of o-aminosulfinylimines in good yields with good to excellent diastereoselectivities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
