4.7 Article

A ratiometric fluorescent sensor based on g-CNQDs@Zn-MOF for the sensitive detection of riboflavin via FRET

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2020.119004

Keywords

Ratiometric; Fluorescence detection; g-CNQDs@Zn-MOF; Riboflavin

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Funding

  1. National Natural Science Foundation of China [21576138, 51872140, 51972173]
  2. Program for Science and Technology Innovative Research Team in Universities of Jiangsu Province, China

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A novel ratiometric fluorescent sensor based on a FRET platform was developed for the detection of riboflavin, using g-CNQDs@Zn-MOF as the fluorescent probe. The sensor exhibited high sensitivity and selectivity to riboflavin, with a detection limit of 15 nM, showing potential for various applications in detecting riboflavin.
A novel ratiometric fluorescent sensor based on Forster resonance energy transfer (FRET) platform was designed for riboflavin (RF) detection. The graphitic carbon nitrides quantum dots Zn-MOF composite (g-CNQDs@Zn-MOF) was used as the fluorescent probe. In the FRET system, g-CNQDs@Zn-MOF and RF acted as donor and acceptor, respectively. The probe exhibited high sensitivity and good selectivity to RF, and had been successfully used for the detection of RF in milk and vitamin B-2 tablets. The detection limit of the sensor was 15 nM. The strategy expanded the application of MOF in sensing filed and provided a new method for the detection of RF. (c) 2020 Elsevier B.V. All rights reserved.

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