Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 331, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2020.129394
Keywords
Fluorescent probe; H2S; Cys; Hcy; GSH; Single-molecule
Funding
- Natural Science Foundation of Hunan Province, China [2019JJ40360]
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A single-molecular fluorescent probe KC was developed for discriminative detection of H2S, Cys, Hcy, and GSH with distinct fluorescence signals. This probe enabled the discriminatory visualization of these four thiol-containing substrates in cells and zebrafish.
A single-molecular, selective and sensitive fluorescent probe, KC, was developed to discriminatively detect H2S, Cys, Hcy, and GSH with concise fluorescence signals. Probe KC displayed distinct fluorescence signals in response to these four biological thiols: H2S (red), Cys (blue), Hcy (blue-green) and GSH (green). The discriminatory visualization of these four thiol-containing substrates in cells and zebrafish were realized with the help of this probe.
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