Factors influencing the spatial distribution of cystic echinococcosis in Tibet, China

Cystic echinococcosis (CE), which is caused by Echinococcus granulosus , is a worldwide helminthozoonosis that is highly endemic in the Tibet Autonomous Region of China and has important public health and economic impacts. However, the spatial epidemiological characteristics of CE in Tibet are still unclear. Based on recorded human CE cases and the use of a geographic information system, the spatial distribution patterns of CE prevalence at three different scales were analyzed. In addition, a spatial agglomeration map of CE prevalence was generated based on cold/hot spot analysis. By combining maps of environmental and biological covariates with information about known human CE cases, the links between CE prevalence and relevant covariates were explored, revealing that the annual average precipitation, elevation, water accessibility and animal population (dog and yak) were associated with the prevalence of CE at the significance level of P < 0.05. Our results provide a novel insight and better understanding of the current situation of and the factors influencing CE in Tibet, which can help public health authorities develop disease prevention and control strategies. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

The study analyzed the spatial distribution and clustering of cystic echinococcosis (CE) prevalence in Tibet, revealing associations with annual average precipitation, elevation, water accessibility, and animal population. This provides insights for understanding the current situation of and factors influencing CE in Tibet, aiding in the development of disease prevention and control strategies by public health authorities.