4.4 Article

Gender differences in the experience of psychotic-like experiences and their associated factors: A study of adolescents from the general population

Journal

SCHIZOPHRENIA RESEARCH
Volume 228, Issue -, Pages 410-416

Publisher

ELSEVIER
DOI: 10.1016/j.schres.2021.01.008

Keywords

Psychotic-like experiences; Subclinical psychotic experiences; Psychosis; Mental health; Adolescents

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Funding

  1. NHMRC Career Development Fellowship [1148793]

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Research in adolescents found significant gender differences in experiencing PLEs, with females reporting higher levels of PLEs but similar associations with stress, anxiety, and depression as males. However, males showed a stronger association between daily hassles and PLEs compared to females. Therefore, interventions targeting daily life stress may need to consider the emotional perception of stress in females and everyday life hassles in males.
Psychotic-Like Experiences (PLEs) are common in the general population. While they are usually transient and resolve spontaneously, they can be distressing and signify increased risk for later psychosis or other psychopathology. It is important to investigate factors associated with PLEs which could be targeted to reduce their prevalence and impact. Males and females are known to experience PLEs differently, but any gender differences in the relationships between PLEs and other, potentially targetable, factors are currently unknown. 302 adolescents (175 females, mean age = 16.03, SD = 0.75; 127 males, mean age = 16.09, SD = 0.74) from secondary schools in the West Midlands region of the UK completed baseline self-report measures of positive PLEs, measured by the Community Assessment of Psychic Experiences (CAPE-P), and several potentially related factors including: cannabis use, perceived stress, anxiety, depression, and daily hassles. PLEs were common in this sample, with 67.5% of individuals experiencing at least one CAPE-P item 'often' or 'almost always'. Females reported significantly higher levels of PLEs, and associated distress, than males. Anxiety, depressive, and stress symptoms were similarly associated with PLEs in both genders. However, there was a significant interaction of gender and daily hassles in the association with PLEs. In summary, there were significant gender differences in the experience of PLEs in this sample. Although daily hasslesweremore common in females, they had a significantly stronger associationwith PLEs inmales. Thus, addressing daily life stress in adolescents may require tailoring towards the more emotional perception of stress in females, and towards everyday life hassles in males. (C) 2021 Elsevier B.V. All rights reserved.

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