Journal
REVIEWS IN MEDICAL VIROLOGY
Volume 31, Issue 6, Pages -Publisher
WILEY
DOI: 10.1002/rmv.2223
Keywords
COVID-19; dimorphism; sex
Categories
Funding
- Projekt DEAL
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Males have shown a bias in severity and mortality in the current COVID-19 pandemic caused by SARS-CoV-2, in line with previous coronavirus outbreaks. Research discussing the sex differences in COVID-19 aims to inform risk stratification and therapeutic options.
The current coronavirus disease (COVID-19) pandemic caused by novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a male bias in severity and mortality. This is consistent with previous coronavirus pandemics such as SARS-CoV and MERS-CoV, and viral infections in general. Here, we discuss the sex-disaggregated epidemiological data for COVID-19 and highlight underlying differences that may explain the sexual dimorphism to help inform risk stratification strategies and therapeutic options.
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