GIGANTEA confers susceptibility to plants during spot blotch attack by regulating salicylic acid signalling pathway

Plants throughout their development are challenged by different abiotic and biotic stresses. Growth and developmental plasticity of a plant is under the strict surveillance of the diurnal and circadian control mechanism, fine-tuned by the biological clock. Success of plant life-cycle resides on the continual battle against pathogen that they encounter at different developmental stages. GIGANTEA (GI), a higher plant specific nuclear protein, has been shown to play a major role in shaping plant development by coupling clock function to the circadian phasing of gene expression in Arabidopsis. Despite the central role of GI in regulating light signalling, clock function, flowering time control and in abiotic stress tolerance, its possible function in pathogen defence is not well known. Here we show that, GI expression positively correlates with susceptibility of plants to the spot blotch pathogen infection in both Arabidopsis and bread wheat. Furthermore, we also show that GI expression promotes disease severity by down regulating the salicylic acid (SA) accumulation and alters the phenyl-propanoid pathway, thereby suppressing PR gene expression. It is possible that GI-mediated regulation of SA signalling may be one of the possible ways of coupling the light-temperature input pathway to pathogen defence through circadian clock. Our results indicate that the down-regulation of GI could be beneficial in generating disease tolerant crop plants for sustainable agriculture.

Automated summary

Plants face different stresses during their development, with the GIGANTEA (GI) protein playing a key role in regulating plant development and defense mechanisms. GI expression correlates with susceptibility to pathogen infection and can down-regulate salicylic acid accumulation, thus affecting disease severity. This suggests that GI could potentially be targeted for generating disease tolerant crop plants for sustainable agriculture.