Quantitative analysis of glucose by using (PVP and MA) capped silver nanoparticles for biosensing applications

Sensing and quantification of glucose molecules are of significant value for the food and pharmaceutical industries. The pure and capped (PVP and MA) silver NPs were synthesized by a low-cost solution evaporation method. Structural properties including the crystallite size of pure and capped silver NPs were calculated by XRD while surface morphology was investigated by SEM. Furthermore, the presence of various functional groups (OH, CH3 and COO-) attached to the surface of silver NPs was confirmed via FTIR spectra and red shift appeared for PVP capped spectra between 360 and 440 nm. The PVP coated Ag nano-composite biosensor exhibited very quick significant stable potentiometric response as compared to pure and MA capped biosensor which enhanced the sensitivity, stability and immobilization rate due to small size, uniform surface morphology and high absorbance rate. In an overall assessment, the synthesized PVP coated Ag-based biosensor is potentially feasible for clinical diagnosis and related applications.

Automated summary

The study synthesized pure and capped silver NPs, analyzed structural and surface morphology through XRD and SEM, confirmed functional groups attachment through FTIR spectra, and found PVP coated Ag nano-composite biosensor exhibited excellent performance.