Related references
Note: Only part of the references are listed.Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1
Yue Hu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2
Yue Hu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Analysis of nonideality: insights from high concentration simulations of sedimentation velocity data
J. J. Correia et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2020)
Characterization of therapeutic antibodies in the presence of human serum proteins by AU-FDS analytical ultracentrifugation
Robert T. Wright et al.
ANALYTICAL BIOCHEMISTRY (2018)
Determination of Interaction Parameters for Reversibly Self-Associating Antibodies: A Comparative Analysis
Mandi M. Hopkins et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2018)
Weak IgG self- and hetero-association characterized by fluorescence analytical ultracentrifugation
Danlin Yang et al.
PROTEIN SCIENCE (2018)
Challenges in Predicting Protein-Protein Interactions from Measurements of Molecular Diffusivity
Lea L. Sorret et al.
BIOPHYSICAL JOURNAL (2016)
Mitigation of reversible self-association and viscosity in a human IgG1 monoclonal antibody by rational, structure-guided Fv engineering
James C. Geoghegan et al.
MABS (2016)
Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity
Jayant Arora et al.
MABS (2016)
Technical Decision-Making with Higher Order Structure Data: Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It
Julie Y. Wei et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Mechanism of Reversible Self-Association of a Monoclonal Antibody: Role of Electrostatic and Hydrophobic Interactions
Reza Esfandiary et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody
Jayant Arora et al.
MABS (2015)
Examination of the dynamic assembly equilibrium for E-coli ClpB
JiaBei Lin et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2015)
The therapeutic monoclonal antibody market
Dawn M. Ecker et al.
MABS (2015)
Accelerated Formulation Development of Monoclonal Antibodies (mAbs) and mAb-Based Modalities: Review of Methods and Tools
Vladimir I. Razinkov et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
Complement Is Activated by IgG Hexamers Assembled at the Cell Surface
Christoph A. Diebolder et al.
SCIENCE (2014)
A Systematic Multitechnique Approach for Detection and Characterization of Reversible Self-Association during Formulation Development of Therapeutic Antibodies
Reza Esfandiary et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Developments and Challenges for mAb-Based Therapeutics
Sumit Goswami et al.
ANTIBODIES (2013)
Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release
Wim Jiskoot et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Solution pH That Minimizes Self-Association of Three Monoclonal Antibodies Is Strongly Dependent on Ionic Strength
Shantanu V. Sule et al.
MOLECULAR PHARMACEUTICS (2012)
The use of analytical sedimentation velocity to extract thermodynamic linkage
James L. Cole et al.
BIOPHYSICAL CHEMISTRY (2011)
Phase Separation of an IgG1 Antibody Solution under a Low Ionic Strength Condition
Hirotaka Nishi et al.
PHARMACEUTICAL RESEARCH (2010)
Mechanisms of Protein Aggregation
John S. Philo et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2009)
High concentration formulations of recombinant human interleukin-1 receptor antagonist: II. Aggregation kinetics
John R. Alford et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Improved calculation of rotational diffusion and intrinsic viscosity of bead models for macromolecules and nanoparticles
J. Garcia de la Torre et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2007)
Improved methods for fitting sedimentation coefficient distributions derived by time-derivative techniques
John S. Philo
ANALYTICAL BIOCHEMISTRY (2006)
Interpretation of the temperature dependence of equilibrium and rate constants
Donald J. Winzor et al.
JOURNAL OF MOLECULAR RECOGNITION (2006)
Analysis of heterologous interacting systems by sedimentation velocity: curve fitting algorithms for estimation of sedimentation coefficients, equilibrium and kinetic constants
WF Stafford et al.
BIOPHYSICAL CHEMISTRY (2004)
A comparison of weight average and direct boundary fitting of sedimentation velocity data for indefinite polymerizing systems
CA Sontag et al.
BIOPHYSICAL CHEMISTRY (2004)
Challenges in the development of high protein concentration formulations
SJ Shire et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
van't Hoff and calorimetric enthalpies from isothermal titration calorimetry: Are there significant discrepancies?
JR Horn et al.
BIOCHEMISTRY (2001)
Share Paper
