4.3 Article

Three-dimensional versus two-dimensional postmortem ultrasound: feasibility in perinatal death investigation

Journal

PEDIATRIC RADIOLOGY
Volume 51, Issue 7, Pages 1259-1266

Publisher

SPRINGER
DOI: 10.1007/s00247-020-04934-4

Keywords

Autopsy; Foetus; Pathology; Perinatal; Postmortem; Three-dimensional ultrasound; Ultrasound

Funding

  1. European Society of Paediatric Radiology
  2. RCUK/UKRI Innovation Fellowship
  3. Medical Research Council (MRC) Clinical Research Training Fellowship [MR/R002118/1]
  4. Royal College of Radiologists (RCR)
  5. National Institute for Health Research (NIHR) Career Development Fellowship [NIHR-CDF-2017-10-037]
  6. MRC
  7. RCR
  8. NIHR

Ask authors/readers for more resources

A study conducted 2-D and 3-D postmortem ultrasound on 11 fetuses, showing that 3-D did not provide additional information compared to 2-D, therefore routine 3-D postmortem ultrasound is not recommended based on the findings.
Three- and four-dimensional US techniques in antenatal screening are commonplace, but they are not routinely used for perinatal postmortem US. In this technical innovation, we performed both two-dimensional (2-D) and three-dimensional (3-D) postmortem US on 11 foetuses (mean gestation: 23 weeks; range: 15-32 weeks) to determine whether there was any benefit in 3-D over conventional 2-D methods. In one case of osteogenesis imperfecta, both 2-D and 3-D US images were non-diagnostic because of small foetal size. Of the remaining 10 foetuses, 7 were normal at imaging and autopsy, and 3 had abnormalities detected on both 2-D and 3-D US. There were no false-positive diagnoses by 2-D or 3-D US. Whilst 3-D postmortem US was a feasible technique, it did not provide additional information over 2-D US. Routine 3-D postmortem US cannot therefore be routinely recommended based on our findings.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.3
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available