Journal
PARKINSONISM & RELATED DISORDERS
Volume 84, Issue -, Pages 144-145Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2021.02.017
Keywords
Subpopulations of monocytes; FACS; Cerebrospinal fluid; Peripheral blood; Pbmc; Innate immune system; Flow cytometry; Biomarker
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Funding
- EU/EFPIA Innovative Medicines Initiative Joint Undertaking (Aetionomy) [115568]
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Classical and nonclassical monocytes were found to be increased in the cerebrospinal fluid of Parkinson's Disease patients.
We performed immune cell profiling by multiparameter flow cytometry in cerebrospinal fluid (CSF) and peripheral blood (PB) of Parkinson's Disease (PD) patients (n = 9) and healthy controls (n = 8). Classical and nonclassical monocytes were increased in the CSF of PD patients.
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