4.8 Article

Halotrifluoromethylation of 1,3-Enynes: Access to Tetrasubstituted Allenes

Related references

Note: Only part of the references are listed.
Article Chemistry, Organic

Copper and Zinc Copromoted Bromo(chloro)trifluoromethylation of Alkenes and Alkynes with Trifluoromethanesulfonic Anhydride

Yao Ouyang et al.

Summary: The first copper and zinc copromoted trifluoromethylation using trifluoromethanesulfonic anhydride (Tf2O) as a trifluoromethylating reagent has been developed, affording bromo(chloro)trifluoromethylated products in good yields. CuX2 plays a dual role as the catalyst and halide source, whereas 2,2'-bipyridine acts as both the activation reagent and ligand.

ORGANIC LETTERS (2021)

Article Chemistry, Organic

Trifluoromethylthiolation, Trifluoromethylation, and Arylation Reactions of Difluoro Enol Silyl Ethers

Xingguo Jiang et al.

JOURNAL OF ORGANIC CHEMISTRY (2020)

Review Chemistry, Applied

Progress in Electrochemical Trifluoromethylation Reactions

Rasmi P. Bhaskaran et al.

ADVANCED SYNTHESIS & CATALYSIS (2020)

Article Multidisciplinary Sciences

Current Contributions of Organofluorine Compounds to the Agrochemical Industry

Yuta Ogawa et al.

ISCIENCE (2020)

Review Biochemistry & Molecular Biology

Halogen-Induced Controllable Cyclizations as Diverse Heterocycle Synthetic Strategy

Hideyasu China et al.

MOLECULES (2020)

Article Chemistry, Multidisciplinary

Practical and regioselective halo-trifluoromethylthiolation of sulfur ylides

Hongmei Qin et al.

CHEMICAL COMMUNICATIONS (2020)

Review Chemistry, Multidisciplinary

Fluorine-Containing Drugs Approved by the FDA in 2018

Haibo Mei et al.

CHEMISTRY-A EUROPEAN JOURNAL (2019)

Review Chemistry, Multidisciplinary

Approaches to Obtaining Fluorinated α-Amino Acids

Johann Moschner et al.

CHEMICAL REVIEWS (2019)

Article Chemistry, Organic

Trifluoromethylations of Alkenes Using PhICF3Cl as Bifunctional Reagent

Cong Xu et al.

JOURNAL OF ORGANIC CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Synthesis of Chlorotrifluoromethylated Pyrrolidines by Electrocatalytic Radical Ene-Yne Cyclization

Ke-Yin Ye et al.

CHEMISTRY-A EUROPEAN JOURNAL (2018)

Article Chemistry, Medicinal

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

Nicholas A. Meanwell

JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Anodically Coupled Electrolysis for the Heterodifunctionalization of Alkenes

Ke-Yin Ye et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Stereoselective cobalt-catalyzed halofluoroalkylation of alkynes

Guojiao Wu et al.

CHEMICAL SCIENCE (2018)

Review Chemistry, Multidisciplinary

Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations

Fei Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

Article Chemistry, Organic

A NaSO2CF3/NaBrO3-mediated bromotrifluoromethylation of enyne via free-radical cascade processes

Xiao-Jie Shang et al.

ORGANIC CHEMISTRY FRONTIERS (2018)

Article Chemistry, Organic

syn-Fluoro- and -Oxy-trifluoromethylation of Arylacetylenes

Song-Lin Zhang et al.

ORGANIC LETTERS (2017)

Review Chemistry, Physical

Recent advances in catalytic asymmetric synthesis of allenes

Wen-Dao Chu et al.

CATALYSIS SCIENCE & TECHNOLOGY (2017)

Review Chemistry, Multidisciplinary

Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes

Maxence Bos et al.

CHEMISTRY-A EUROPEAN JOURNAL (2017)

Article Chemistry, Multidisciplinary

Practical Photocatalytic Trifluoromethylation and Hydrotrifluoromethylation of Styrenes in Batch and Flow

Natan J. W. Straathof et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Organic

Copper-Catalyzed Intermolecular Chloro- and Bromotrifluoromethylation of Alkenes

Mingyang Fu et al.

ORGANIC LETTERS (2016)

Article Chemistry, Multidisciplinary

Trifluoromethylchlorosulfonylation of Alkenes: Evidence for an Inner-Sphere Mechanism by a Copper Phenanthroline Photoredox Catalyst

Dattatraya B. Bagal et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Multidisciplinary Sciences

A scalable and operationally simple radical trifluoromethylation

Joel W. Beatty et al.

NATURE COMMUNICATIONS (2015)

Article Chemistry, Multidisciplinary

A General Synthesis of Fluoroalkylated Alkenes by Palladium-Catalyzed Heck-Type Reaction of Fluoroalkyl Bromides

Zhang Feng et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Review Chemistry, Multidisciplinary

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

Xiao Liu et al.

CHEMICAL REVIEWS (2015)

Review Chemistry, Multidisciplinary

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

Julie Charpentier et al.

CHEMICAL REVIEWS (2015)

Review Chemistry, Multidisciplinary

Palladium-Catalyzed Cyclization Reactions of Allenes in the Presence of Unsaturated Carbon-Carbon Bonds

Juntao Ye et al.

ACCOUNTS OF CHEMICAL RESEARCH (2014)

Article Chemistry, Multidisciplinary

Controlled Trifluoromethylation Reactions of Alkynes through Visible-Light Photoredox Catalysis

Naeem Iqbal et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Review Chemistry, Multidisciplinary

Trifluoromethylation of Alkenes with Concomitant Introduction of Additional Functional Groups

Hiromichi Egami et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Iron- Catalyzed 1,2-Addition of Perfluoroalkyl Iodides to Alkynes and Alkenes

Tao Xu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Review Chemistry, Multidisciplinary

Addition of CF3 across unsaturated moieties: a powerful functionalization tool

Estibaliz Merino et al.

CHEMICAL SOCIETY REVIEWS (2014)

Review Chemistry, Inorganic & Nuclear

Successful fluorine-containing herbicide agrochemicals

Tomoya Fujiwara et al.

JOURNAL OF FLUORINE CHEMISTRY (2014)

Review Chemistry, Organic

Conquering three-carbon axial chirality of allenes

Juntao Ye et al.

Organic Chemistry Frontiers (2014)

Article Chemistry, Multidisciplinary

Oxidative Trifluoromethylation of Unactivated Olefins: An Efficient and Practical Synthesis of α-Trifluoromethyl-Substituted Ketones

Arghya Deb et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Article Chemistry, Multidisciplinary

Directing-Group-Assisted Copper-Catalyzed Olefinic Trifluoromethylation of Electron-Deficient Alkenes

Chao Feng et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)

Review Chemistry, Multidisciplinary

A Renaissance in Radical Trifluoromethylation

Armido Studer

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Review Chemistry, Multidisciplinary

Allenes in Catalytic Asymmetric Synthesis and Natural Product Syntheses

Shichao Yu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Article Chemistry, Multidisciplinary

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

Chao Feng et al.

CHEMICAL SCIENCE (2012)

Review Chemistry, Multidisciplinary

Transition Metal Catalyzed Cycloisomerizations of 1,n-Allenynes and -Allenenes

Corinne Aubert et al.

CHEMICAL REVIEWS (2011)

Review Chemistry, Multidisciplinary

Aromatic Trifluoromethylation with Metal Complexes

Olesya A. Tomashenko et al.

CHEMICAL REVIEWS (2011)

Review Multidisciplinary Sciences

Catalysis for fluorination and trifluoromethylation

Takeru Furuya et al.

NATURE (2011)

Review Chemistry, Multidisciplinary

Fluorine in medicinal chemistry

Sophie Purser et al.

CHEMICAL SOCIETY REVIEWS (2008)

Review Multidisciplinary Sciences

Fluorine in pharmaceuticals:: Looking beyond intuition

Klaus Mueller et al.

SCIENCE (2007)

Review Chemistry, Inorganic & Nuclear

Strategies for nucleophilic, electrophilic, and radical trifluoromethylations

Jun-An Ma et al.

JOURNAL OF FLUORINE CHEMISTRY (2007)

Article Chemistry, Multidisciplinary

Novel 10-I-3 hypervalent iodine-based compounds for electrophilic trifluoromethylation

P Eisenberger et al.

CHEMISTRY-A EUROPEAN JOURNAL (2006)

Review Chemistry, Multidisciplinary

Some typical advances in the synthetic applications of allenes

SM Ma

CHEMICAL REVIEWS (2005)

Review Chemistry, Multidisciplinary

Asymmetric fluorination, trifluoromethylation, and perfluoroalkylation reactions

JA Ma et al.

CHEMICAL REVIEWS (2004)

Review Chemistry, Multidisciplinary

Synthesis and properties of allenic natural products and pharmaceuticals

A Hoffmann-Roder et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)