Journal
ORAL DISEASES
Volume 28, Issue -, Pages 2522-2529Publisher
WILEY
DOI: 10.1111/odi.13816
Keywords
-
Categories
Funding
- Korea University [K1824471]
Ask authors/readers for more resources
The study found that periodontitis is associated with an increased risk of acute and chronic coronary syndrome. Periodontitis has a greater link with acute coronary syndrome incidence in males, younger adults, smokers, and subjects without hypertension, and with chronic coronary syndrome incidence in smokers, subjects without hypertension, and subjects without dyslipidaemia.
Objective To investigate the role of periodontitis in the risk of acute and chronic coronary syndrome with compounding factors, including sociodemographic factors and medication use. Methods This retrospective cohort study used nationwide, population-based data from the Korean National Health Insurance Service-Health Screening Cohort database (514,866 individuals, 40-79 years). Propensity score matching was used for analysis. Information of subjects for 12 years was included. Socioeconomic and clinical factors were recorded and analysed. Results The periodontitis group had a greater risk of overall acute coronary syndrome (hazard ratio [95% confidence interval] =1.25 [1.15, 1.35], p < .001) and non-fatal acute coronary syndrome (1.26 [1.16, 1.37], p < .001). The hazard ratio for chronic coronary syndrome was higher in patients with periodontitis (1.35 [1.25, 1.46], p < .001). The cumulative incidence of both acute and chronic coronary syndrome gradually increased, and the hazard ratios reached 1.25 and 1.35 at the 12-year follow-up, respectively. Subgroup analysis revealed that periodontitis had a significantly greater link with acute coronary syndrome incidence in males, younger adults, smokers and subjects without hypertension (p < .01) and with chronic coronary syndrome incidence in smokers, subjects without hypertension and subjects without dyslipidaemia (p < .05). Conclusions Periodontitis is associated with an increased risk of acute and chronic coronary syndrome.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available