Construction of octahedral SERS blotting imprinted sensor for selective detection of 2,6-dichlorophenol

MIPs and surface enhanced Raman scattering (SERS) technology are combined to construct a new type of sensor for selective detection of chlorophenols. The SERS substrates are synthesized by loading Ag nanoparticles on MIL-101 (Fe). Then, the Ag@MIL-101 (Fe)@MIPs is obtained by precipitation polymerization with using 2,6-DCP as the template and acrylamide as the functional monomer. The synthesized MIL-101 (Fe) is found to be an octahedral structure. The prepared Ag@MIL-101 (Fe)@MIPs shows huge SERS activity. In the range of 103109 mol/L, the prepared sensor for detecting 2,6-DCP has a linear relationship between SERS intensity at the peak of 1575 cm-1 and 2,6-DCP concentration, the detection limit is 4.5 nmol/L, and the imprinting factor is 2.2. The sensor is used for actual sample analysis, with a recovery rate of 96.58%-105.56%, and a relative standard deviation (R2) of 1.355%-3.861%. The metal MOF-based nanocomposite prepared in this study can be used as a promising SERS substrate material. This method which is combined by MIPs and SERS provides a new detection method for the detection of 2,6-DCP and other chlorophenols, and expandes new technical fields.

Automated summary

The study developed a new sensor for selective detection of chlorophenols by combining MIPs and SERS technology, using Ag nanoparticles on MIL-101 (Fe) to synthesize SERS substrates, and synthesizing Ag@MIL-101(Fe)@MIPs with significant SERS activity via precipitation polymerization. The sensor showed promising results in actual sample analysis with good recovery rate and relative standard deviation.