Related references
Note: Only part of the references are listed.Resistance to Avapritinib in PDGFRA-Driven GIST Is Caused by Secondary Mutations in the PDGFRA Kinase Domain
Susanne Grunewald et al.
CANCER DISCOVERY (2021)
Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial
Michael C Heinrich et al.
LANCET ONCOLOGY (2020)
Switch Control Inhibition of KIT and PDGFRA in Patients With Advanced Gastrointestinal Stromal Tumor: A Phase I Study of Ripretinib
Filip Janku et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor
Gerardo A. Vitiello et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
Delphine Goehrig et al.
GUT (2019)
Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
E. Hessmann et al.
GUT (2018)
GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells
Shu Z. Wiley et al.
FASEB JOURNAL (2018)
Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor
Phillip Zook et al.
CLINICAL CANCER RESEARCH (2017)
Platelet-derived growth factor-C promotes human melanoma aggressiveness through activation of neuropilin-1
Federica Ruffini et al.
ONCOTARGET (2017)
Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit
Lexun Wang et al.
MEDICAL SCIENCE MONITOR (2017)
SLUG transcription factor: a pro-survival and prognostic factor in gastrointestinal stromal tumour
Olli-Pekka Pulkka et al.
BRITISH JOURNAL OF CANCER (2017)
FGFR1 and NTRK3 actionable alterations in Wild-Type gastrointestinal stromal tumors
Eileen Shi et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2016)
Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition
Esther Ekpe-Adewuyi et al.
ONCOTARGET (2016)
Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic
Sosipatros A. Boikos et al.
JAMA ONCOLOGY (2016)
The biology and function of fibroblasts in cancer
Raghu Kalluri
NATURE REVIEWS CANCER (2016)
Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1
Yujiro Hayashi et al.
GASTROENTEROLOGY (2015)
KIT and PDGFRA Mutations and the Risk of GI Stromal Tumor Recurrence
Heikki Joensuu et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Phosphoinositide 3-Kinase Inhibitors Combined with Imatinib in Patient-Derived Xenograft Models of Gastrointestinal Stromal Tumors: Rationale and Efficacy
Thomas Van Looy et al.
CLINICAL CANCER RESEARCH (2014)
Fibroblast heterogeneity in the cancer wound
Daniel Oehlund et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
Giuseppe Floris et al.
CLINICAL CANCER RESEARCH (2013)
Optimizing Surgical and Imatinib Therapy for the Treatment of Gastrointestinal Stromal Tumors
Jason K. Sicklick et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2013)
Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial
George D. Demetri et al.
LANCET (2013)
Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth
Badreddin Edris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis
Mark A. Eckert et al.
CANCER CELL (2011)
Gastrointestinal stromal tumours: origin and molecular oncology
Christopher L. Corless et al.
NATURE REVIEWS CANCER (2011)
A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors
P. Schoffski et al.
ANNALS OF ONCOLOGY (2010)
Ligand-Dependent Platelet-Derived Growth Factor Receptor (PDGFR)-α Activation Sensitizes Rare Lung Cancer and Sarcoma Cells to PDGFR Kinase Inhibitors
Ultan McDermott et al.
CANCER RESEARCH (2009)
Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts
Charlotte Anderberg et al.
CANCER RESEARCH (2009)
Molecular pathobiology of gastrointestinal stromal sarcomas
Christopher L. Corless et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)
Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells
Pravin J. Mishra et al.
CANCER RESEARCH (2008)
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033
Charles D. Blanke et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
George D. Demetri et al.
LANCET (2006)
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
A Duensing et al.
ONCOGENE (2004)
Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-αα and -αβ receptors
RH Cao et al.
FASEB JOURNAL (2002)
Conventional and molecular cytogenetic characterization of a new human cell line, GIST-T1, established from gastrointestinal stromal tumor
T Taguchi et al.
LABORATORY INVESTIGATION (2002)
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications
DA Tuveson et al.
ONCOGENE (2001)
PDGF-C is a new protease-activated ligand for the PDGF α-receptor
XR Li et al.
NATURE CELL BIOLOGY (2000)