4.5 Article

Transient monocular visual impairment as an initial symptom of COVID-19 infection in an individual with multiple sclerosis receiving teriflunomide

Journal

NEUROLOGICAL SCIENCES
Volume 42, Issue 5, Pages 1661-1664

Publisher

SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10072-021-05097-2

Keywords

COVID-19; Multiple sclerosis; Teriflunomide

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A multiple sclerosis patient treated with teriflunomide did not interrupt treatment during a COVID-19 infection, resulting in a mild course of infection. It may be considered that teriflunomide is a safe disease-modifying treatment option during the pandemic, as observed in this case.
In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various neurological symptoms have been also described in patients with COVID-19. Here, we report an unusual presentation of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not interrupt teriflunomide treatment during the infection. The course of the infection was mild in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people with MS (pwMS). It can also be concluded that teriflunomide may be considered a safe disease-modifying treatment option during the pandemic.

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