Related references
Note: Only part of the references are listed.Combination therapy for non-alcoholic steatohepatitis: rationale, opportunities and challenges
Jean-Francois Dufour et al.
GUT (2020)
Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress
Christiane Rennert et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Soy Food Intake Is Inversely Associated with Newly Diagnosed Nonalcoholic Fatty Liver Disease in the TCLSIH Cohort Study
Shunming Zhang et al.
JOURNAL OF NUTRITION (2020)
Global Perspectives on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
Zobair Younossi et al.
HEPATOLOGY (2019)
Effect of Genistein on Cholesterol Metabolism-Related Genes in HepG2 Cell
Rongrong Lu et al.
JOURNAL OF FOOD SCIENCE (2019)
Molecular insights into the role of mitochondria in non-alcoholic fatty liver disease
Jin Lee et al.
ARCHIVES OF PHARMACAL RESEARCH (2019)
Protective effect of genistein on nonalcoholic fatty liver disease (NAFLD)
Xin Xin et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Leonurus japonicus Houtt Attenuates Nonalcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Cells and Mice Fed a High-Fat Diet
Mi-Ra Lee et al.
NUTRIENTS (2018)
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
David Hojland Ipsen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Genistein supplementation improves insulin resistance and inflammatory state in non-alcoholic fatty liver patients: A randomized, controlled trial
Sasan Amanat et al.
CLINICAL NUTRITION (2018)
Molecular Actions of PPARα in Lipid Metabolism and Inflammation
Nadia Bougarne et al.
ENDOCRINE REVIEWS (2018)
Peroxisome proliferator-activated receptor alpha-mediated drug toxicity in the liver
Maka S. Hedrington et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2018)
In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model
Antonietta Stellavato et al.
LIPIDS IN HEALTH AND DISEASE (2018)
Mitochondrial adaptation in steatotic mice
Claudia Einer et al.
MITOCHONDRION (2018)
Human-based systems: Mechanistic NASH modelling just around the corner?
Joost Boeckmans et al.
PHARMACOLOGICAL RESEARCH (2018)
Nonalcoholic fatty liver disease: current concepts, epidemiology and management strategies
Dunya Tomic et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2018)
Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
Francis W. B. Sanders et al.
GENOME BIOLOGY (2018)
A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis
Christin Wallstab et al.
FEBS JOURNAL (2017)
Genistein Ameliorates Fat Accumulation Through AMPK Activation in Fatty Acid-Induced BRL Cells
Huijia Zhong et al.
JOURNAL OF FOOD SCIENCE (2017)
Genistein has beneficial effects on hepatic steatosis in high fat-high sucrose diet-treated rats
Huanhuan Liu et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
The role and regulation of the peroxisome proliferator activated receptor alpha in human liver
Sander Kersten et al.
BIOCHIMIE (2017)
Global Epidemiology of Nonalcoholic Fatty Liver Disease-Meta-Analytic Assessment of Prevalence, Incidence, and Outcomes
Zobair M. Younossi et al.
HEPATOLOGY (2016)
NAFLD and liver transplantation: Current burden and expected challenges
Raluca Pais et al.
JOURNAL OF HEPATOLOGY (2016)
The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
Elena Buzzetti et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
Non-alcoholic Fatty Liver Disease: Beneficial Effects of Flavonoids
Masoumeh Akhlaghi
PHYTOTHERAPY RESEARCH (2016)
Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells
Victoria Kegel et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)
Free Fatty Acids Impair FGF21 Action in HepG2 Cells
Mohamed Asrih et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
Nonalcoholic Steatohepatitis Is the Second Leading Etiology of Liver Disease Among Adults Awaiting Liver Transplantation in the United States
Robert J. Wong et al.
GASTROENTEROLOGY (2015)
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
Michal Pawlak et al.
JOURNAL OF HEPATOLOGY (2015)
Long-chain acyl-CoA synthetase in fatty acid metabolism involved in liver and other diseases: An update
Sheng Yan et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2015)
Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells
Elisa Pfeiffer et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2015)
Soy foods, isoflavones, and the health of postmenopausal women
Mark Messina
AMERICAN JOURNAL OF CLINICAL NUTRITION (2014)
Protective Effect of the Y220C Mutant p53 Against Steatosis: Good News?
Manuele Gori et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2014)
Debate: A Bridge Too Far-Liver Transplantation for Nonalcoholic Steatohepatitis Will Overwhelm the Organ Supply
Julie Heimbach
LIVER TRANSPLANTATION (2014)
PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells
Alexandra Rogue et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)
How useful are clinical liver function tests in in vitro human hepatotoxicity assays?
Juergen Borlak et al.
TOXICOLOGY IN VITRO (2014)
Hepatic Fatty Acid Trafficking: Multiple Forks in the Road
Douglas G. Mashek
ADVANCES IN NUTRITION (2013)
Ligand-dependent nucleo-cytoplasmic shuttling of peroxisome proliferator-activated receptors, PPARα and PPARγ
Tomoe Umemoto et al.
GENES TO CELLS (2012)
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
Tamas Varga et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Neonatal exposure to genistein ameliorates high-fat diet-induced non-alcoholic steatohepatitis in rats
Chengfei Huang et al.
BRITISH JOURNAL OF NUTRITION (2011)
Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c
P. Ferre et al.
DIABETES OBESITY & METABOLISM (2010)
Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-alpha expression, a novel mechanism for the pathogenesis of NAFLD
Lin Zheng et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2010)
Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease
Rakesh P. Patel et al.
PPAR RESEARCH (2010)
Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human
Maryam Rakhshandehroo et al.
PLOS ONE (2009)
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
Nobito Higuchi et al.
HEPATOLOGY RESEARCH (2008)
Preventive role of genistein in an experimental non-alcoholic steatohepatitis model
Mehmet Yalniz et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2007)
Peroxisome proliferator-activated receptor α protects against obesity-induced hepatic inflammation
Rinke Stienstra et al.
ENDOCRINOLOGY (2007)
Genistein downregulates SREBP-1 regulated gene expression by inhibiting site-1 protease expression in HepG2 cells
Eui Seok Shin et al.
JOURNAL OF NUTRITION (2007)
A human hepatocellular in vitro model to investigate steatosis
Maria Jose Gomez-Lechon et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2007)
Effects of dietary genistein on hepatic lipid metabolism and mitochondrial function in mice fed high-fat diets
Young Min Lee et al.
NUTRITION (2006)
Preparation of ready-to-use, storable and reconstituted type I collagen from rat tail tendon for tissue engineering applications
Navneeta Rajan et al.
NATURE PROTOCOLS (2006)
Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c
BD Hegarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Global suppression of IL-6-induced acute phase response gene expression after chronic in vivo treatment with the peroxisome proliferator-activated receptor-α activator fenofibrate
P Gervois et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Retinoic acid receptor α dominant negative form causes steatohepatitis and liver tumors in transgenic mice
A Yanagitani et al.
HEPATOLOGY (2004)
Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARα
S Kim et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
G Marchesini et al.
HEPATOLOGY (2003)
Peroxisome proliferator-activated receptor α (PPARα) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes
C Blanquart et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
S Seki et al.
JOURNAL OF HEPATOLOGY (2002)
Dietary polyunsaturated fatty acids and regulation of gene transcription
DB Jump
CURRENT OPINION IN LIPIDOLOGY (2002)
Isoflavonoids and lignans have different potentials to modulate oxidative genetic damage in human colon cells
BL Pool-Zobel et al.
CARCINOGENESIS (2000)