Journal
MOLECULES
Volume 26, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/molecules26040927
Keywords
bacterial pigments; Pseudomonas aeruginosa; pyocyanase; bioprospecting
Funding
- CAPES-Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior [88882.440710/2019-01]
- Universidade Federal da Paraiba
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Pyocyanin, the first natural phenazine described, is synthesized by around 95% of Pseudomonas aeruginosa strains. It has a rich history, being used in antimicrobial therapy and electric current generation, and has a vibrant blue color.
Pyocyanin was the first natural phenazine described. The molecule is synthesized by about 95% of the strains of Pseudomonas aeruginosa. From discovery up to now, pyocyanin has been characterised by a very rich and avant-garde history, which includes its use in antimicrobial therapy, even before the discovery of penicillin opened the era of antibiotic therapy, as well as its use in electric current generation. Exhibiting an exuberant blue colour and being easy to obtain, this pigment is the subject of the present review, aiming to narrate its history as well as to unveil its mechanisms and suggest new horizons for applications in different areas of engineering, biology and biotechnology.
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