Journal
MOLECULES
Volume 26, Issue 4, Pages -Publisher
MDPI
DOI: 10.3390/molecules26040844
Keywords
green synthesis; silver nanoparticle; gold nanoparticle; nanoparticle characterization; antimicrobial activity; toxicity
Funding
- National Research, Development and Innovation Office-NKFIH [GINOP-2.3.2-15-2016-00038, GINOP-2.3.2-15-2016-00035, EFOP-3.6.1-16-201600008]
- Palyazat_kodja_elneve zeseSorsz grant of the New National Excellence Program of the Ministry for Innovation and Technology
- Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [BO/00878/19/8]
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The nanomaterial industry produces large quantities of metal-based nanomaterials for various applications, but the use of toxic chemicals for production burdens the environment. Green synthetic approaches have emerged to provide eco-friendly alternative methods and reduce the ecological footprint.
The nanomaterial industry generates gigantic quantities of metal-based nanomaterials for various technological and biomedical applications; however, concomitantly, it places a massive burden on the environment by utilizing toxic chemicals for the production process and leaving hazardous waste materials behind. Moreover, the employed, often unpleasant chemicals can affect the biocompatibility of the generated particles and severely restrict their application possibilities. On these grounds, green synthetic approaches have emerged, offering eco-friendly, sustainable, nature-derived alternative production methods, thus attenuating the ecological footprint of the nanomaterial industry. In the last decade, a plethora of biological materials has been tested to probe their suitability for nanomaterial synthesis. Although most of these approaches were successful, a large body of evidence indicates that the green material or entity used for the production would substantially define the physical and chemical properties and as a consequence, the biological activities of the obtained nanomaterials. The present review provides a comprehensive collection of the most recent green methodologies, surveys the major nanoparticle characterization techniques and screens the effects triggered by the obtained nanomaterials in various living systems to give an impression on the biomedical potential of green synthesized silver and gold nanoparticles.
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