4.6 Review

Microglia Biomarkers in Alzheimer's Disease

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer's Disease Brains

Douglas G. Walker et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Neurosciences

Association study of serum soluble TREM2 with vascular dementia in Chinese Han population

Qian Wang et al.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2020)

Review Neurosciences

Genetics of Alzheimer's disease: where we are, and where we are going

Celine Bellenguez et al.

CURRENT OPINION IN NEUROBIOLOGY (2020)

Review Biochemistry & Molecular Biology

New fluid biomarkers tracking non-amyloid-β and non-tau pathology in Alzheimer's disease

Sun Ah Park et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models

Christian Sacher et al.

JOURNAL OF NUCLEAR MEDICINE (2020)

Article Cell Biology

β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia

Lea L. Friker et al.

CELL REPORTS (2020)

Article Neurosciences

Dynamic changes of CSF sTREM2 in preclinical Alzheimer's disease: the CABLE study

Ling-Zhi Ma et al.

MOLECULAR NEURODEGENERATION (2020)

Review Immunology

TREM2 ectodomain and its soluble form in Alzheimer's disease

Jiaolong Yang et al.

JOURNAL OF NEUROINFLAMMATION (2020)

Article Biochemistry & Molecular Biology

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease

Simon Dujardin et al.

NATURE MEDICINE (2020)

Review Immunology

Investigating Microglia in Health and Disease: Challenges and Opportunities

Veronique E. Miron et al.

TRENDS IN IMMUNOLOGY (2020)

Article Clinical Neurology

Cerebrospinal Fluid and Blood CX3CL1 as a Potential Biomarker in Early Diagnosis and Prognosis of Dementia

Agnieszka Kulczynska-Przybik et al.

CURRENT ALZHEIMER RESEARCH (2020)

Review Cell Biology

Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging

Hiroshi Nakanishi

NEURAL REGENERATION RESEARCH (2020)

Article Clinical Neurology

2020 Alzheimer's disease facts and figures

[Anonymous]

ALZHEIMERS & DEMENTIA (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice

Carola Focke et al.

JOURNAL OF NUCLEAR MEDICINE (2019)

Article Immunology

Glial activation and inflammation along the Alzheimer's disease continuum

Kaja Nordengen et al.

JOURNAL OF NEUROINFLAMMATION (2019)

Article Geriatrics & Gerontology

CSF soluble TREM2 as a measure of immune response along the Alzheimer's disease continuum

Boris-Stephan Rauchmann et al.

NEUROBIOLOGY OF AGING (2019)

Article Multidisciplinary Sciences

Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Daniel Felsky et al.

NATURE COMMUNICATIONS (2019)

Article Clinical Neurology

In vivo direct relation of tau pathology with neuroinflammation in early Alzheimer's disease

Tatsuhiro Terada et al.

JOURNAL OF NEUROLOGY (2019)

Article Neurosciences

TREM2 function impedes tau seeding in neuritic plaques

Cheryl E. G. Leyns et al.

NATURE NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer's disease

Estrella Morenas-Rodriguez et al.

SCIENTIFIC REPORTS (2019)

Review Neurosciences

The neuropathological diagnosis of Alzheimer's disease

Michael A. DeTure et al.

MOLECULAR NEURODEGENERATION (2019)

Article Clinical Neurology

Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's disease

Simon Sjodin et al.

ALZHEIMERS RESEARCH & THERAPY (2019)

Review Geriatrics & Gerontology

Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities

Anne-Laure Hemonnot et al.

FRONTIERS IN AGING NEUROSCIENCE (2019)

Article Immunology

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model

Yang Shi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2019)

Article Multidisciplinary Sciences

NLRP3 inflammasome activation drives tau pathology

Christina Ising et al.

NATURE (2019)

Article Multidisciplinary Sciences

Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model

Elizabeth Spangenberg et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Extra-axonal restricted diffusion as an in-vivo marker of reactive microglia

Maxime Taquet et al.

SCIENTIFIC REPORTS (2019)

Article Clinical Neurology

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers

Nicholas J. Ashton et al.

ALZHEIMERS RESEARCH & THERAPY (2019)

Article Cell Biology

TET2 Regulates the Neuroinflammatory Response in Microglia

Alejandro Carrillo-Jimenez et al.

CELL REPORTS (2019)

Article Neurosciences

Microglial motility in Alzheimer's disease and after Aβ42 immunotherapy: a human post-mortem study

Diana K. Franco-Bocanegra et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3

Judith Houtman et al.

EMBO JOURNAL (2019)

Article Neurosciences

CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model

Dylan J. Finneran et al.

JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2019)

Article Neurosciences

Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

Samira Parhizkar et al.

NATURE NEUROSCIENCE (2019)

Article Multidisciplinary Sciences

PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R)

Andrew G. Horti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Medicine, General & Internal

Microglia express GPNMB in the brains of Alzheimer's disease and Nasu-Hakola disease

Jun-ichi Satoh et al.

INTRACTABLE & RARE DISEASES RESEARCH (2019)

Review Cell Biology

Microglia in Alzheimer's disease

David V. Hansen et al.

JOURNAL OF CELL BIOLOGY (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

Neuroinflammation Appears Early on PET Imaging and Then Plateaus in a Mouse Model of Alzheimer Disease

Francisco R. Lopez-Picon et al.

JOURNAL OF NUCLEAR MEDICINE (2018)

Review Neurosciences

Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease

Kevin M. Budge et al.

MOLECULAR NEUROBIOLOGY (2018)

Review Biochemistry & Molecular Biology

Markers of microglia in post-mortem brain samples from patients with Alzheimer's disease: a systematic review

K. E. Hopperton et al.

MOLECULAR PSYCHIATRY (2018)

Review Clinical Neurology

The lysosomal function of progranulin, a guardian against neurodegeneration

Daniel H. Paushter et al.

ACTA NEUROPATHOLOGICA (2018)

Review Clinical Neurology

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

Clifford R. Jack et al.

ALZHEIMERS & DEMENTIA (2018)

Article Oncology

Cathepsin B links oxidative stress to the activation of NLRP3 inflammasome

Hua Bai et al.

EXPERIMENTAL CELL RESEARCH (2018)

Review Biochemistry & Molecular Biology

Microglia and Aging: The Role of the TREM2-DAP12 and CX3CL1-CX3CR1 Axes

Carmen Mecca et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Immunology

Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease

Alicia Lopez et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Review Pharmacology & Pharmacy

The role of TAM family receptors and ligands in the nervous system: From development to pathobiology

Bridget Shafit-Zagardo et al.

PHARMACOLOGY & THERAPEUTICS (2018)

Article Clinical Neurology

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment

Yonatan A. Cooper et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2018)

Article Biochemistry & Molecular Biology

Altered Processing of β-Amyloid in SH-SY5Y Cells Induced by Model Senescent Microglia

Dafina M. Angelova et al.

ACS CHEMICAL NEUROSCIENCE (2018)

Review Neurosciences

Microglia in neurodegeneration

Suzanne Hickman et al.

NATURE NEUROSCIENCE (2018)

Article Neurosciences

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease

Bahareh Eftekharzadeh et al.

NEURON (2018)

Article Radiology, Nuclear Medicine & Medical Imaging

[18F]F-DPA for the detection of activated microglia in a mouse model of Alzheimer's disease

Thomas Keller et al.

NUCLEAR MEDICINE AND BIOLOGY (2018)

Article Multidisciplinary Sciences

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy

Faten A. Sayed et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Clinical Neurology

Cerebrospinal fluid soluble TREM2 levels in frontotemporal dementia differ by genetic and pathological subgroup

Ione O. C. Woollacott et al.

ALZHEIMERS RESEARCH & THERAPY (2018)

Article Neurosciences

Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer's Disease

Juan R. Perea et al.

FRONTIERS IN NEUROSCIENCE (2018)

Review Clinical Neurology

Current state of Alzheimer's fluid biomarkers

Jose Luis Molinuevo et al.

ACTA NEUROPATHOLOGICA (2018)

Article Medicine, Research & Experimental

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline

Marc Suárez‐Calvet et al.

EMBO Molecular Medicine (2018)

Article Immunology

CSF sTREM2 in deliriumrelation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau

Kristi Henjum et al.

JOURNAL OF NEUROINFLAMMATION (2018)

Article Neurosciences

Glycoprotein NMB: a novel Alzheimer's disease associated marker expressed in a subset of activated microglia

Melanie Huettenrauch et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state

Alessandro Villa et al.

THERANOSTICS (2018)

Review Immunology

The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection

Fernanda M. Marim et al.

SEMINARS IN IMMUNOPATHOLOGY (2017)

Article Immunology

Soluble TREM2 induces inflammatory responses and enhances microglial survival

Li Zhong et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Multidisciplinary Sciences

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

Cheryl E. G. Leyns et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs

Zhiyuan Niu et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease

Hadas Keren-Shaul et al.

Article Clinical Neurology

Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network

Hideyuki Takahashi et al.

ACTA NEUROPATHOLOGICA (2017)

Article Neurosciences

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis

Mingqin Zhu et al.

MOLECULAR NEUROBIOLOGY (2016)

Article Biochemistry & Molecular Biology

Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease

Willem Kamphuis et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)

Article Radiology, Nuclear Medicine & Medical Imaging

Decreased in vivo availability of the cannabinoid type 2 receptor in Alzheimer's disease

Rawaha Ahmad et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2016)

Article Neurosciences

Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease

Amanda Heslegrave et al.

MOLECULAR NEURODEGENERATION (2016)

Article Geriatrics & Gerontology

Neuronal driven pre-plaque inflammation in a transgenic rat model of Alzheimer's disease

Cecilia E. Hanzel et al.

NEUROBIOLOGY OF AGING (2014)

Article Clinical Neurology

rs5848 polymorphism and serum progranulin level

Ging-Yuek R. Hsiung et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2011)

Article Endocrinology & Metabolism

Caspase-mediated degradation of PPARγ proteins in adipocytes

Fang He et al.

OBESITY (2008)