Complete vs partial fundoplication: a laboratory measurement of functionality and effectiveness

Background Complete or partial fundoplication remains controversial for the surgical treatment of GERD. While partial fundoplication is considered less effective, it is associated with less post-operative dysphagia and gas bloating compared with complete fundoplication. Aim To compare the mechanical efficiency of the three different types of fundoplication. Material and method Two studies of the LES were performed on explanted stomachs: distensibility and failure point. Measurements were taken before and after fundoplication. Results There was no difference in distensibility between Nissen and Toupet fundoplication, however, the EGJ was more distensible following Dor fundoplication. According to failure point measurements, Nissen fundoplication was significantly more effective than Toupet, Toupet was significantly more effective than Dor (p = .016, p = .017, respectively). Conclusions There were significant differences in distensibility between Dor and both Nissen and Toupet, however no statistical difference between Toupet and Nissen. There was a significant difference in effectiveness between all three types of fundoplication according to the failure point. These laboratory findings demonstrate that the mechanical orientation of Nissen and Toupet have similar functionality suggesting that Toupet is as good as Nissen. While in clinical studies Toupet has fewer post-operative complications these findings support the proponents of Toupet for GERD.

Automated summary

Complete or partial fundoplication for GERD surgery is controversial. Partial fundoplication is associated with less post-operative complications, but less effective. Comparing mechanical efficiency reveals Nissen fundoplication to be the most effective, followed by Toupet and Dor fundoplication. These findings suggest that Toupet may be as good as Nissen in clinical practice.