A high efficiency N, P doped porous carbon nanoparticles derived from lotus leaves for simultaneous electrochemical determination of ascorbic acid, dopamine, and uric acid

A kind of phosphorus doped nitrogenous porous carbon material (CNP) has been prepared from lotus leaves to fabricate a novel electrochemical sensor for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). Detailed characteristics of the as-prepared porous carbon were investigated by SEM, BET, XPS, XRD and Raman analysis. The electrochemical behaviors of the modified electrode were explored by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CNP/GCE demonstrated linear response ranges of 20 ?M?250 ?M for AA, 10 ?M?480 ?M for DA, and 25 ?M?2500 ?M for UA, with detection limits (S/N = 3) of 4.25 ?M, 0.86 ?M, and 0.20 ??, respectively. Furthermore, the CNP/GCE has been successfully applied to determine AA, DA and UA in real serum samples, which exhibited excellent reproducibility, anti-interference and stability.

Automated summary

The phosphorus-doped nitrogenous porous carbon material was used to fabricate an electrochemical sensor for simultaneous determination of ascorbic acid, dopamine, and uric acid. The sensor showed excellent linear response ranges and detection limits for the three substances, and performed well in real serum sample analysis.