Journal
MEDICINE
Volume 100, Issue 4, Pages -Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MD.0000000000023635
Keywords
meta-analysis; parotid tumors; superb microvascular imaging
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Funding
- Liaoning Natural Science Foundation [20180550612, 20170540256]
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This study aims to systematically evaluate the accuracy of superb microvascular imaging (SMI) in the differentiation between benign and malignant parotid tumors, providing valuable evidence for its clinical application in this context.
Background: As a novel ultrasound technique, superb microvascular imaging (SMI) can quickly, simply, and noninvasively study the microvascular distribution in the tumor and evaluate the microvascular perfusion. Studies suggested that SMI is helpful for the differentiation between benign and malignant parotid tumors. However, the results of these studies have been contradictory. Therefore, the present meta-analysis aimed at determining the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors. Methods: We will search PubMed, Web of Science, Cochrane Library, and Chinese biomedical databases from their inceptions to September 30, 2020, without language restrictions. Two authors will independently carry out searching literature records, scanning titles and abstracts, full texts, collecting data, and assessing risk of bias. Review Manager 5.2 and Stata14.0 software will be used for data analysis. Results: This systematic review will determine the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors. Conclusion: Its findings will provide helpful evidence for the accuracy of SMI in the differential diagnosis between benign and malignant parotid tumors. Systematic review registration: INPLASY2020100093
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