4.5 Article

Temperature-based MRI safety simulations with a limited number of tissues

Journal

MAGNETIC RESONANCE IN MEDICINE
Volume 86, Issue 1, Pages 543-550

Publisher

WILEY
DOI: 10.1002/mrm.28693

Keywords

MRI; safety; SAR; simulation; temperature

Funding

  1. National Institutes of Health [P41 EB017183]

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The study demonstrates that reasonable temperature estimates can be simulated with a limited number of tissues in numerical models of the human body, although this number is higher than the number of tissues required to produce reasonable simulations of specific absorption rate. Inclusion of a few additional tissues can produce results in much better agreement with those from the original model.
Purpose: Demonstrate ability to produce reasonable simulations of temperature using numerical models of the human body with a limited number of tissues. Methods: For both a male and female human body model, numerical simulations were used to calculate temperature distributions in three different models of the same human body: the original model with 35 tissues for the male model and 76 tissues for the female model, a simplified model having only three tissues (muscle, fat, and lung), and a simplified model having six tissues (muscle, fat, lung, bone, brain, and skin). Results: Although a three-tissue model gave reasonable specific absorption rate estimates in comparison to an original with many more tissues, because of tissue-specific thermal and physiological properties that do not affect specific absorption rate, such as rate of perfusion by blood, the three-tissue model did not provide-temperature distributions similar to those of the original model. Inclusion of a few additional tissues, as in the six-tissue model, produced results in much better agreement with those from the original model. Conclusion: Reasonable estimates of temperature can be simulated with a limited number of tissues, although this number is higher than the number of tissues required to produce reasonable simulations of specific absorption rate. For exposures primarily in the head and thorax, six tissues may be adequate for reasonable estimates of temperature.

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