Journal
LANCET
Volume 397, Issue 10277, Pages 928-940Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0140-6736(21)00458-X
Keywords
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Categories
Funding
- Global Initiative for Asthma
- Global Initiative for COPD
- Global Asthma Network
- Pan African Thoracic Society
- British Thoracic Society Global Health Group
- European Respiratory Society
- Asian Pacific Society of Respirology
- Asociacion Latinoamericana de Torax
- World Health Organization
- National Institute for Health Research (NIHR) Global Health Research Unit on Lung Health and TB in Africa at the Liverpool School of Tropical Medicine (IMPALA) [16/136/35]
- NIHR using UK aid from the UK Government
- MRC [MR/S002359/1, MR/P008984/1, MR/S02042X/1] Funding Source: UKRI
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Low-income and middle-income countries bear a high burden of global morbidity and mortality caused by chronic respiratory diseases, with challenges in prevention, diagnosis, and management. Solutions are needed to achieve true universal health coverage in LMICs.
Low-income and middle-income countries (LMICs) bear a disproportionately high burden of the global morbidity and mortality caused by chronic respiratory diseases (CRDs), including asthma, chronic obstructive pulmonary disease, bronchiectasis, and post-tuberculosis lung disease. CRDs are strongly associated with poverty, infectious diseases, and other non-communicable diseases (NCDs), and contribute to complex multi-morbidity, with major consequences for the lives and livelihoods of those affected. The relevance of CRDs to health and socioeconomic wellbeing is expected to increase in the decades ahead, as life expectancies rise and the competing risks of early childhood mortality and infectious diseases plateau. As such, the World Health Organization has identified the prevention and control of NCDs as an urgent development issue and essential to the achievement of the Sustainable Development Goals by 2030. In this Review, we focus on CRDs in LMICs. We discuss the early life origins of CRDs; challenges in their prevention, diagnosis, and management in LMICs; and pathways to solutions to achieve true universal health coverage.
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