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Effects of Adrenal Sensitivity, Stress- and Cue-Induced Craving, and Anxiety on Subsequent Alcohol Relapse and Treatment Outcomes
Rajita Sinha et al.
ARCHIVES OF GENERAL PSYCHIATRY (2011)
A genetic determinant of the striatal dopamine response to alcohol in men
V. A. Ramchandani et al.
MOLECULAR PSYCHIATRY (2011)
Pharmacogenetic approaches to the treatment of alcohol addiction
Markus Heilig et al.
NATURE REVIEWS NEUROSCIENCE (2011)
In vitro and in vivo characterization of the novel GABAB receptor positive allosteric modulator, 2-{1-[2-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-yl]-2-piperidinyl}ethanol (CMPPE)
Elisabetta Perdona et al.
NEUROPHARMACOLOGY (2011)
Synaptic and Morphological Neuroadaptations in the Putamen Associated with Long-Term, Relapsing Alcohol Drinking in Primates
Verginia C. Cuzon Carlson et al.
NEUROPSYCHOPHARMACOLOGY (2011)
Enhanced Sensitivity to Attenuation of Conditioned Reinstatement by the mGluR2/3 Agonist LY379268 and Increased Functional Activity of mGluR2/3 in Rats with a History of Ethanol Dependence
Peter R. Kufahl et al.
NEUROPSYCHOPHARMACOLOGY (2011)
Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors
Haowei Shen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The stimulating effects of ethanol on ventral tegmental area dopamine neurons projecting to the ventral pallidum and medial prefrontal cortex in female Wistar rats: regional difference and involvement of serotonin-3 receptors
Zheng-Ming Ding et al.
PSYCHOPHARMACOLOGY (2011)
Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429
Jesse R. Schank et al.
PSYCHOPHARMACOLOGY (2011)
New Findings on Biological Factors Predicting Addiction Relapse Vulnerability
Rajita Sinha
CURRENT PSYCHIATRY REPORTS (2011)
The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons
Mary Kay Lobo et al.
FRONTIERS IN NEUROANATOMY (2011)
Relapse prevention for addictive behaviors
Christian S. Hendershot et al.
SUBSTANCE ABUSE TREATMENT PREVENTION AND POLICY (2011)
Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease
Colleen M. Niswender et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
Effects of the mGlu2/3 Agonist LY379268 and the mGlu5 Antagonist MTEP on Ethanol Seeking and Reinforcement Are Differentially Altered in Rats with a History of Ethanol Dependence
Nimish Sidhpura et al.
BIOLOGICAL PSYCHIATRY (2010)
Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin
Remi Martin-Fardon et al.
BRAIN RESEARCH (2010)
The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors
M. R. Bruchas et al.
BRAIN RESEARCH (2010)
MULTICENTER, RANDOMIZED, DOUBLE-BLIND, ACTIVE COMPARATOR AND PLACEBO-CONTROLLED TRIAL OF A CORTICOTROPIN-RELEASING FACTOR RECEPTOR-1 ANTAGONIST IN GENERALIZED ANXIETY DISORDER
Vladimir Coric et al.
DEPRESSION AND ANXIETY (2010)
Long-Lasting Adaptations of the NR2B-Containing NMDA Receptors in the Dorsomedial Striatum Play a Crucial Role in Alcohol Consumption and Relapse
Jun Wang et al.
JOURNAL OF NEUROSCIENCE (2010)
Neurocircuitry of Addiction
George F. Koob et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Long-Evans Rats Acquire Operant Self-Administration of 20% Ethanol Without Sucrose Fading
Jeffrey A. Simms et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
Stephen F. Traynelis et al.
PHARMACOLOGICAL REVIEWS (2010)
Modulation of alcohol and nicotine responses through the endogenous opioid system
Eva Drews et al.
PROGRESS IN NEUROBIOLOGY (2010)
Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking
Andrea Cippitelli et al.
PSYCHOPHARMACOLOGY (2010)
Role of the GABAB receptor system in alcoholism and stress: focus on clinical studies and treatment perspectives
Giovanni Addolorato et al.
ALCOHOL (2009)
Parallel and interactive learning processes within the basal ganglia: Relevance for the understanding of addiction
David Belin et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Roles of opioid receptor subtypes in mediating alcohol-seeking induced by discrete cues and context
Peter W. Marinelli et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Paraventricular thalamus mediates context-induced reinstatement (renewal) of extinguished reward seeking
Adam S. Hamlin et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Interoceptive Effects of Alcohol Require mGlu5 Receptor Activity in the Nucleus Accumbens
Joyce Besheer et al.
JOURNAL OF NEUROSCIENCE (2009)
GABA(A) receptors: Subtypes provide diversity of function and pharmacology
Richard W. Olsen et al.
NEUROPHARMACOLOGY (2009)
Involvement of Amygdala Dopamine and Nucleus Accumbens NMDA Receptors in Ethanol-Seeking Behavior in Mice
Christina M. Gremel et al.
NEUROPSYCHOPHARMACOLOGY (2009)
Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior
Rainer Spanagel
PHYSIOLOGICAL REVIEWS (2009)
Contingent and non-contingent effects of low-dose ethanol on GABA neuron activity in the ventral tegmental area
Scott C. Steffensen et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2009)
Ethanol seeking triggered by environmental context is attenuated by blocking dopamine D1 receptors in the nucleus accumbens core and shell in rats
Nadia Chaudhri et al.
PSYCHOPHARMACOLOGY (2009)
The role of GABAA receptors in the acute and chronic effects of ethanol: a decade of progress
Sandeep Kumar et al.
PSYCHOPHARMACOLOGY (2009)
Effect of naltrexone during extinction of alcohol-reinforced responding and during repeated cue-conditioned reinstatement sessions in a cue exposure style treatment
Keith L. Williams et al.
ALCOHOL (2008)
Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats
J. Besheer et al.
ALCOHOL (2008)
A 6-week randomized, placebo-controlled trial of CP-316,311 (a selective CRH1 antagonist) in the treatment of major depression
Brendon Binneman et al.
AMERICAN JOURNAL OF PSYCHIATRY (2008)
Acute effect of methadone maintenance dose on brain fMRI response to heroin-related cues
Daniel D. Langleben et al.
AMERICAN JOURNAL OF PSYCHIATRY (2008)
Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala Crhr1 expression following a history of dependence
Wolfgang H. Sommer et al.
BIOLOGICAL PSYCHIATRY (2008)
Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats
Paola Maccioni et al.
DRUG AND ALCOHOL DEPENDENCE (2008)
Cocaine seeking habits depend upon doparnine-dependent serial connectivity linking the ventral with the dorsal striatum
David Belin et al.
NEURON (2008)
Cue-induced reinstatement of alcohol-seeking behavior is associated with increased ERK1/2 phosphorylation in specific limbic brain regions:: Blockade by the mGluR5 antagonist MPEP
Jason P. Schroeder et al.
NEUROPHARMACOLOGY (2008)
GABAA receptors and alcohol
Ingrid A. Lobo et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)
The role of GABAA receptors in the development of alcoholism
Mary-Anne Enoch
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)
Neurokinin 1 receptor antagonism as a possible therapy for alcoholism
David T. George et al.
SCIENCE (2008)
Pharmacological evidence for a motivational role of κ-opioid systems in ethanol dependence
Brendan M. Walker et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study
Giovanni Addolorato et al.
LANCET (2007)
Long-acting κ opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase
Michael R. Bruchas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Compulsive drug seeking by rats under punishment: effects of drug taking history
Yann Pelloux et al.
PSYCHOPHARMACOLOGY (2007)
A key role for corticotropin-releasing factor in alcohol dependence
Markus Heilig et al.
TRENDS IN NEUROSCIENCES (2007)
The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking
Alexander Kuzmin et al.
NEUROPSYCHOPHARMACOLOGY (2007)
3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine:: A novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism
Donald R. Gehlert et al.
JOURNAL OF NEUROSCIENCE (2007)
Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABA(A) alpha 1 subunit null mutant mice
Harry L. June et al.
NEUROPSYCHOPHARMACOLOGY (2007)
GABA and glycine as neurotransmitters: a brief history
NG Bowery et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Baclofen-induced suppression of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats exposed to different alcohol concentrations
Giancarlo Colombo et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse
Valentina Vengeliene et al.
FASEB JOURNAL (2006)
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure
David H. Epstein et al.
PSYCHOPHARMACOLOGY (2006)
Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress
A. C. Hansson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala
Yu Zhao et al.
JOURNAL OF NEUROSCIENCE (2006)
GABAB receptor:: a site of therapeutic benefit
NG Bowery
CURRENT OPINION IN PHARMACOLOGY (2006)
Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse
C Sanchis-Segura et al.
JOURNAL OF NEUROSCIENCE (2006)
Projections from bed nuclei of the stria terminalis, anteromedial area: Cerebral hemisphere integration of neuroendocrine, autonomic, and behavioral aspects of energy balance
HW Dong et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2006)
Effects of chronic alcohol and repeated deprivations on dopamine D1 and D2 receptor levels in the extended amygdala of inbred alcohol-preferring rats
Y Sari et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2006)
Molecular diversity, trafficking and subcellular localization of GABA(B) receptors
Bernhard Bettler et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms
Markus Heilig et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG
P Bäckström et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2005)
Prolonged central μ-opioid receptor occupancy after single and repeated nalmefene dosing
K Ingman et al.
NEUROPSYCHOPHARMACOLOGY (2005)
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
BJ Everitt et al.
NATURE NEUROSCIENCE (2005)
The neural basis of addiction: A pathology of motivation and choice
PW Kalivas et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat
D Bachteler et al.
NEUROPSYCHOPHARMACOLOGY (2005)
The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect
V Vengeliene et al.
NEUROPHARMACOLOGY (2005)
Role of alpha-2 adrenoceptors in stress-induced reinstatement of alcohol seeking and alcohol self-administration in rats
AD Lê et al.
PSYCHOPHARMACOLOGY (2005)
GABAB receptor modulators potentiate baclofen-induced depression of dopamine neuron activity in the rat ventral tegmental area
Y Chen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2005)
Correlation of stable elevations in striatal mu-opioid receptor availability in detoxified alcoholic patients with alcohol craving - A positron emission tomography study using carbon 11-labeled carfentanil
A Heinz et al.
ARCHIVES OF GENERAL PSYCHIATRY (2005)
Projections from bed nuclei of the stria terminalis, posterior division: Implications for cerebral hemisphere regulation of defensive and reproductive behaviors
HW Dong et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2004)
Ethanol drinking and deprivation alter dopaminergic and serotonergic function in the nucleus accumbens of alcohol-preferring rats
RJ Thielen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Effects of raclopride in the core of the nucleus accumbens on ethanol seeking and consumption: The use of extinction trials to measure seeking
HH Samson et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2004)
Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behavior
P Bäckström et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2004)
Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
K Ebner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats
R Ciccocioppo et al.
PSYCHOPHARMACOLOGY (2004)
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior
K McFarland et al.
JOURNAL OF NEUROSCIENCE (2004)
Tachykinins and tachykinin receptors: a growing family
JN Pennefather et al.
LIFE SCIENCES (2004)
GABAA and opioid receptors of the central nucleus of the amygdala selectively regulate ethanol-maintained behaviors
KL Foster et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Evidence for addiction-like behavior in the rat
V Deroche-Gamonet et al.
SCIENCE (2004)
Drug seeking becomes compulsive after prolonged cocaine self-administration
LJMJ Vanderschuren et al.
SCIENCE (2004)
Increased GABA release in the central amygdala of ethanol-dependent rats
M Roberto et al.
JOURNAL OF NEUROSCIENCE (2004)
Corticotropin-releasing factor in brain: A role in activation, arousal, and affect regulation
SC Heinrichs et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Pharmacological properties of JDTic:: a novel κ-opioid receptor antagonist
I Carroll et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Role of GABA(B) receptor in alcohol dependence: Reducing effect of baclofen on alcohol intake and alcohol motivational properties in rats and amelioration of alcohol withdrawal syndrome and alcohol craving in human alcoholics
G Colombo et al.
NEUROTOXICITY RESEARCH (2004)
mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior
P Bäckström et al.
NEUROPSYCHOPHARMACOLOGY (2004)
The reinforcing properties of alcohol are mediated by GABAA1 receptors in the ventral pallidum
HL June et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Impulse activity of midbrain dopamine neurons modulates drug-seeking behavior
M Marinelli et al.
PSYCHOPHARMACOLOGY (2003)
N-methyl-D-aspartate glutamate receptors and alcoholism:: reward, dependence, treatment, and vulnerability
JH Krystal et al.
PHARMACOLOGY & THERAPEUTICS (2003)
GABAA receptor α1 and β2 subunit null mutant mice:: Behavioral responses to ethanol
YA Blednov et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Suppression by baclofen of alcohol deprivation effect in Sardinian alcohol-preferring (sP) rats
G Colombo et al.
DRUG AND ALCOHOL DEPENDENCE (2003)
Ethanol increases GABAergic transmission at both pre- and postsynaptic sites in rat central amygdala neurons
M Roberto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Effect of selective blockade of μ1 or δ opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats
R Ciccocioppo et al.
NEUROPSYCHOPHARMACOLOGY (2002)
Separate measures of ethanol seeking and drinking in the rat: effects of remoxipride
CL Czachowski et al.
ALCOHOL (2002)
From first drug use to drug dependence: Developmental periods of risk for dependence upon marijuana, cocaine, and alcohol
FA Wagner et al.
NEUROPSYCHOPHARMACOLOGY (2002)
Neurobiology of relapse to alcohol in rats
AD Lê et al.
PHARMACOLOGY & THERAPEUTICS (2002)
GABAA receptor modulation of the rewarding and aversive effects of ethanol
JA Chester et al.
ALCOHOL (2002)
GABAB2 is essential for G-protein coupling of the GABAB receptor heterodimer
MJ Robbins et al.
JOURNAL OF NEUROSCIENCE (2001)
Cocaine-induced conditioned place preference: reinstatement by priming injections of cocaine after extinction
D Mueller et al.
BEHAVIOURAL BRAIN RESEARCH (2000)
Regulation of neurotransmitter release by metabotropic glutamate receptors
J Cartmell et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Nociceptin prevents stress-induced ethanol- but not cocaine-seeking behavior in rats
R Martin-Fardon et al.
NEUROREPORT (2000)
The role of corticotrophin-releasing factor in stress-induced relapse to alcohol-seeking behavior in rats
AD Lê et al.
PSYCHOPHARMACOLOGY (2000)
Synaptic organisation of the basal ganglia
JP Bolam et al.
JOURNAL OF ANATOMY (2000)
The 'ABC' of GABA receptors
J Bormann
TRENDS IN PHARMACOLOGICAL SCIENCES (2000)