Journal
JOURNAL OF NATURAL PRODUCTS
Volume 84, Issue 4, Pages 964-971Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jnatprod.0c00869
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Funding
- Wellcome Trust (UK)
- University of Queensland (Australia)
- Research Stipend Scholarship (RSS) scheme by Australian Government via RMIT University
- Yourgene Health Singapore Pty. Ltd.
- Australian Research Council (ARC) [LP160100058]
- ARC LIEF Scheme [LE170100065]
- Australian Research Council [LE170100065, LP160100058] Funding Source: Australian Research Council
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Phytochemical profiling of Drosera magna extracts revealed the presence of compounds with significant antimicrobial and anthelmintic activities.
Phytochemical profiling was undertaken on the crude extracts of Drosera magna to determine the nature of the chemical constituents present. In total, three new flavonol diglycosides (1-3), one new flavan-3-ol glycoside (4), and 12 previously reported compounds of the flavonol (5, 9), flavan-3-ol (15), flavanone (8), 1,4-napthoquinone (6, 7, 13, 14), 2,3-dehydroxynapthalene-1,4-dione (10-12), and phenolic acid (16) structure classes were isolated and identified. Compounds 1-9, 13, 17, and 18 were assessed for antimicrobial activity, with compounds 6, 7, 8, and 9 showing significant activity. Compounds 1, 2, and 6 were also evaluated for anthelmintic activity against larval forms of Hemonchus contortus, with compound 6 being active.
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