4.7 Article

Targeting mechanosensitive MDM4 promotes lung fibrosis resolution in aged mice

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

You Say You Want a Resolution (of Fibrosis)

Kamran Atabai et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)

Review Pharmacology & Pharmacy

Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma

Daniel J. Tschumperlin et al.

PHARMACOLOGY & THERAPEUTICS (2020)

Article Biochemistry & Molecular Biology

Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration

Morgan L. Locy et al.

SCIENCE SIGNALING (2020)

Article Multidisciplinary Sciences

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Vahid Kheirollahi et al.

NATURE COMMUNICATIONS (2019)

Review Physiology

Mechanisms for the Resolution of Organ Fibrosis

Jeffrey C. Horowitz et al.

PHYSIOLOGY (2019)

Article Critical Care Medicine

Reversing Mechanoinductive DSP Expression by CRISPR/dCas9-mediated Epigenome Editing

Jing Qu et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)

Review Medicine, Research & Experimental

Mechanosensing and fibrosis

Daniel J. Tschumperlin et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Medicine, Research & Experimental

Resolution of organ fibrosis

Joon-Il Jun et al.

JOURNAL OF CLINICAL INVESTIGATION (2018)

Review Biochemistry & Molecular Biology

Extracellular matrix in lung development, homeostasis and disease

Yong Zhou et al.

MATRIX BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Metformin reverses established lung fibrosis in a bleomycin model

Sunad Rangarajan et al.

NATURE MEDICINE (2018)

Review Biochemistry & Molecular Biology

How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?

Brandon J. Aubrey et al.

CELL DEATH AND DIFFERENTIATION (2018)

Article Respiratory System

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli

Amos E. Dodi et al.

RESPIRATORY RESEARCH (2018)

Review Biochemistry & Molecular Biology

Revealing Accessibility of Cryptic Protein Binding Sites within the Functional Collagen Fibril

Cody L. Hoop et al.

BIOMOLECULES (2017)

Review Pathology

Mechanisms of Lung Fibrosis Resolution

Stephan W. Glasser et al.

AMERICAN JOURNAL OF PATHOLOGY (2016)

Review Immunology

Macrophages in Tissue Repair, Regeneration, and Fibrosis

Thomas A. Wynn et al.

IMMUNITY (2016)

Article Biochemistry & Molecular Biology

Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype

Brian D. Southern et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Tunable Crosslinked Cell-Derived Extracellular Matrix Guides Cell Fate

Ramesh Subbiah et al.

MACROMOLECULAR BIOSCIENCE (2016)

Article Multidisciplinary Sciences

Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis

Huaping Chen et al.

NATURE COMMUNICATIONS (2016)

Article Respiratory System

Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis

Carlos Machahua et al.

RESPIRATORY RESEARCH (2016)

Article Physiology

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

Fei Liu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)

Article Geriatrics & Gerontology

Protein glycation - Between tissue aging and protection

Andreas Simm et al.

EXPERIMENTAL GERONTOLOGY (2015)

Article Multidisciplinary Sciences

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

Kyoung Wan Yoon et al.

SCIENCE (2015)

Article Respiratory System

Aging and Lung Disease Clinical Impact and Cellular and Molecular Pathways

Mauricio Rojas et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2015)

Article Critical Care Medicine

Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis An Integral Model

Moises Selman et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2014)

Article Biochemistry & Molecular Biology

Tumor Necrosis Factor-α Accelerates the Resolution of Established Pulmonary Fibrosis in Mice by Targeting Profibrotic Lung Macrophages

Elizabeth F. Redente et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)

Article Pharmacology & Pharmacy

Effects of Chebulic Acid on Advanced Glycation Endproducts-Induced Collagen Cross-Links

Ji-young Lee et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2014)

Article Medicine, Research & Experimental

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice

Shaik O. Rahaman et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Cell Biology

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

Louise Hecker et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Review Geriatrics & Gerontology

Mechanistic links between aging and lung fibrosis

Victor J. Thannickal

BIOGERONTOLOGY (2013)

Review Biochemistry & Molecular Biology

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products

Giancarlo Aldini et al.

FREE RADICAL RESEARCH (2013)

Article Medicine, Research & Experimental

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

Yong Zhou et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Biochemical Research Methods

Protein glycation during aging and in cardiovascular disease

Andreas Simm

JOURNAL OF PROTEOMICS (2013)

Article Plant Sciences

Chebulic acid attenuates ischemia reperfusion induced biochemical alteration in diabetic rats

Narendra Silawat et al.

PHARMACEUTICAL BIOLOGY (2013)

Review Oncology

MDM2, MDMX and p53 in oncogenesis and cancer therapy

Mark Wade et al.

NATURE REVIEWS CANCER (2013)

Article Physiology

Hypermethylation-mediated silencing of p14ARF in fibroblasts from idiopathic pulmonary fibrosis

Jose Cisneros et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)

Article Critical Care Medicine

Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation

Adam J. Booth et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)

Article Biochemistry & Molecular Biology

Matrix Stiffness-Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction

Xiangwei Huang et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)

Article Medicine, General & Internal

Predisposition for Disrepair in the Aged Lung

Viranuj Sueblinvong et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)

Article Biochemistry & Molecular Biology

Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury

Mohammad Naimul Islam et al.

NATURE MEDICINE (2012)

Article Chemistry, Medicinal

Mutagenicity and Oral Toxicity Studies of Terminalia chebula

Ji-hoon Kim et al.

PHYTOTHERAPY RESEARCH (2012)

Article Multidisciplinary Sciences

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

Prakash Ramachandran et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Critical Care Medicine

Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

Michael A. Gibbons et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Critical Care Medicine

Transglutaminase 2 and Its Role in Pulmonary Fibrosis

Keith C. Olsen et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Medicine, Research & Experimental

The three R's of lung health and disease: repair, remodeling, and regeneration

Michael F. Beers et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Review Neurosciences

Elk-1 a transcription factor with multiple facets in the brain

Antoine Besnard et al.

FRONTIERS IN NEUROSCIENCE (2011)

Article Cell Biology

Apoptosis and autoimmune diseases

Shigekazu Nagata

CLEARANCE OF DYING CELLS IN HEALTHY AND DISEASED IMMUNE SYSTEMS (2010)

Article Critical Care Medicine

Workshop on Idiopathic Pulmonary Fibrosis in Older Adults

Richard J. Castriotta et al.

CHEST (2010)

Article Cell Biology

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

Fei Liu et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment

Vivian Barry-Hamilton et al.

NATURE MEDICINE (2010)

Review Rheumatology

The role of defective clearance of apoptotic cells in systemic autoimmunity

Luis E. Munoz et al.

NATURE REVIEWS RHEUMATOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Risk factors for idiopathic pulmonary fibrosis in a Mexican population. A case-control study

Ma. Cecilia Garcia-Sancho Figueroa et al.

RESPIRATORY MEDICINE (2010)

Article Respiratory System

Viral infection and aging as cofactors for the development of pulmonary fibrosis

Payal K Naik et al.

Expert Review of Respiratory Medicine (2010)

Article Biochemistry & Molecular Biology

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Siddhartha Jaiswal et al.

Review Biochemistry & Molecular Biology

Modes of p53 Regulation

Jan-Philipp Kruse et al.

Article Endocrinology & Metabolism

ECM Compliance Regulates Osteogenesis by Influencing MAPK Signaling Downstream of RhoA and ROCK

Chirag B. Khatiwala et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2009)

Article Medicine, Research & Experimental

Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages

Kamran Atabai et al.

JOURNAL OF CLINICAL INVESTIGATION (2009)

Article Cardiac & Cardiovascular Systems

Role of diabetes mellitus and gastro-oesophageal reflux in the aetiology of idiopathic pulmonary fibrosis

Jonathan Gribbin et al.

RESPIRATORY MEDICINE (2009)

Article Biochemistry & Molecular Biology

Acidic domain is indispensable for MDM2 to negatively regulate the acetylation of p53

Qian Wang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Review Gastroenterology & Hepatology

The role of matrix stiffness in regulating cell behavior

Rebecca G. Wells

HEPATOLOGY (2008)

Article Oncology

Mdm2 and Mdm4 loss regulates distinct p53 activities

Juan A. Barboza et al.

MOLECULAR CANCER RESEARCH (2008)

Article Multidisciplinary Sciences

Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysis

Shiamalee Perumal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell Biology

Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix

Pierre-Jean Wipff et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages

Michael Miksa et al.

MOLECULAR MEDICINE (2007)

Article Cell Biology

MDMX: from bench to bedside

Jean-Christophe W. Marine et al.

JOURNAL OF CELL SCIENCE (2007)

Review Oncology

Ageing of the conduit arteries

S. E. Greenwald

JOURNAL OF PATHOLOGY (2007)

Article Gastroenterology & Hepatology

Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC

Alaa Melhem et al.

JOURNAL OF HEPATOLOGY (2006)

Article Biochemistry & Molecular Biology

TNF-α sensitizes normal and fibrotic human lung fibroblasts to Fas-induced apoptosis

SK Frankel et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)

Article Multidisciplinary Sciences

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo

S Francoz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4

JD Grier et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Immunology

Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (fractalkine)

JC Gevrey et al.

JOURNAL OF IMMUNOLOGY (2005)

Article Immunology

Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia

F Leonardi-Essmann et al.

JOURNAL OF NEUROIMMUNOLOGY (2005)

Article Dermatology

ERK activation by mechanical strain is regulated by the small G proteins rac-1 and rhoA

J Laboureau et al.

EXPERIMENTAL DERMATOLOGY (2004)

Review Biochemistry & Molecular Biology

Control of apoptosis by p53

JS Fridman et al.

ONCOGENE (2003)

Article Biochemistry & Molecular Biology

Overexpression of tumor necrosis factor-α diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-β

M Fujita et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2003)

Article Cell Biology

Apoptosis - the p53 network

S Haupt et al.

JOURNAL OF CELL SCIENCE (2003)

Article Critical Care Medicine

Diabetes mellitus may increase risk for idiopathic pulmonary fibrosis

T Enomoto et al.

CHEST (2003)

Article Critical Care Medicine

Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epithelium

S Ghosh et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)

Article Biochemistry & Molecular Biology

The ETS domain transcription factor Elk-1 contains a novel class of repression domain

SH Yang et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)

Article Biochemistry & Molecular Biology

MDMX inhibits the p300/CBP-mediated acetylation of p53

P Sabbatini et al.

DNA AND CELL BIOLOGY (2002)

Article Multidisciplinary Sciences

Identification of a factor that links apoptotic cells to phagocytes

R Hanayama et al.

NATURE (2002)

Article Biochemistry & Molecular Biology

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

R Stad et al.

EMBO REPORTS (2001)

Article Biochemistry & Molecular Biology

Early stages of p53-induced apoptosis are reversible

FJ Geske et al.

CELL DEATH AND DIFFERENTIATION (2001)

Article Biochemistry & Molecular Biology

Effect of collagen turnover on the accumulation of advanced glycation end products

N Verzijl et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Immunology

Nitric oxide-dependent activation of p53 suppresses bleomycin-induced apoptosis in the lung

DW Davis et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)

Article Biochemistry & Molecular Biology

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release

M Schuler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

MdmX protects p53 from Mdm2-mediated degradation

MW Jackson et al.

MOLECULAR AND CELLULAR BIOLOGY (2000)