Construction of electrochemical chiral interface of C3N4/Ppy/ self-assembled polysaccharide

A simple and effective chiral selector is reported baseing on Cu2+ and ?-cyclodextrin (Cu-?-CD), which can be self-assembled with sodium alginate (SA) as a chiral sensor (SA-CD). The composite of C3N4 and Ppy (C3N4/ Ppy) was used as an electroactive material for the enantiomeric selection of tryptophan (Trp) by differential pulse voltammetry (DPV). The sensor was constructed by combining the advantages of polysaccharide SACD and C3N4/Ppy. SA-CD as a chiral selector can provide a large number of chiral sites, and C3N4/Ppy as a substrate material can improve the electrochemical signal. The results showed that the electrochemical signal of C3N4/Ppy/SA-CD modified GCE to L-Trp was higher than that to D-Trp. This was due to the low affinity of C3N4/Ppy/SA-CD modified GCE to L-Trp, which made it easier for L-Trp to penetrate the electrode modified film and reach the electrode surface, resulting in a greater peak current. UV?vis and water contact angle further proved that C3N4/Ppy/SA-CD had higher binding ability to D-Trp. In addition, the sensor had good reproducibility and stability, and can be regarded as a promising platform for chiral sensing.

Automated summary

A simple and effective chiral selector based on Cu2+ and ?-cyclodextrin was reported, which self-assembled with sodium alginate as a chiral sensor. The composite of C3N4 and Ppy was utilized as an electroactive material for enantiomeric selection of tryptophan. The sensor showed good selectivity, low affinity to L-Trp, higher peak current, and stronger binding ability to D-Trp.