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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2017)
Continuous manufacturing via hot-melt extrusion and scale up: regulatory matters
Mohammed Maniruzzaman et al.
DRUG DISCOVERY TODAY (2017)
Conjugation of Hot-Melt Extrusion with High-Pressure Homogenization: a Novel Method of Continuously Preparing Nanocrystal Solid Dispersions
Xingyou Ye et al.
AAPS PHARMSCITECH (2016)
Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A Review
Justin S. LaFountaine et al.
AAPS PHARMSCITECH (2016)
Development of an Ointment Formulation Using Hot-Melt Extrusion Technology
Ajinkya M. Bhagurkar et al.
AAPS PHARMSCITECH (2016)
Melt-Extruded Eudragit® FS-Based Granules for Colonic Drug Delivery
Feng Zhang
AAPS PHARMSCITECH (2016)
Hot Melt Extrusion: Development of an Amorphous Solid Dispersion for an Insoluble Drug from Mini-scale to Clinical Scale
Anjali M. Agrawal et al.
AAPS PHARMSCITECH (2016)
Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation
Hemlata Patil et al.
AAPS PHARMSCITECH (2016)
Influence of pressurized carbon dioxide on ketoprofen-incorporated hot-melt extruded low molecular weight hydroxypropylcellulose
Eman A. Ashour et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2016)
Contribution of hot-melt extrusion technology to advance drug delivery in the 21st century
Roshan V. Tiwari et al.
EXPERT OPINION ON DRUG DELIVERY (2016)
Twin Screw Extruders as Continuous Mixers for Thermal Processing: a Technical and Historical Perspective
Charlie Martin
AAPS PHARMSCITECH (2016)
Advanced Implantable Drug Delivery Systems via Continuous Manufacturing
Mohammed Maniruzzaman et al.
CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS (2016)
Multidrug co-crystals: towards the development of effective therapeutic hybrids
Rajesh Thipparaboina et al.
DRUG DISCOVERY TODAY (2016)
Continuous melt granulation: Influence of process and formulation parameters upon granule and tablet properties
Tinne Monteyne et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)
A novel floating controlled release drug delivery system prepared by hot-melt extrusion
Anh Q. Vo et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2016)
The use of rheology to elucidate the granulation mechanisms of a miscible and immiscible system during continuous twin-screw melt granulation
Tinne Monteyne et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Recent advances in abuse-deterrent technologies for the delivery of opioids
Julien Maincent et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Hot melt extruded transdermal films based on amorphous solid dispersions in Eudragit RS PO: The inclusion of hydrophilic additives to develop moisture-activated release systems
Esra'a Albarahmieh et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Co amorphous systems: A product development perspective
Rahul B. Chavan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Spring and parachute: How cocrystals enhance solubility
Dhara D. Bavishi et al.
PROGRESS IN CRYSTAL GROWTH AND CHARACTERIZATION OF MATERIALS (2016)
Prevalence and Abundance of Florfenicol and Linezolid Resistance Genes in Soils Adjacent to Swine Feedlots
Qin Zhao et al.
SCIENTIFIC REPORTS (2016)
Thin films as an emerging platform for drug delivery
Sandeep Karki et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Distributive mixing elements: Towards improved granule attributes from a twin screw granulation process
R. Sayin et al.
CHEMICAL ENGINEERING SCIENCE (2015)
Polymeric formulations for drug release prepared by hot melt extrusion: application and characterization
Milica Stankovic et al.
DRUG DISCOVERY TODAY (2015)
Implementation of transmission NIR as a PAT tool for monitoring drug transformation during HME processing
Muhammad T. Islam et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)
Improving the API dissolution rate during pharmaceutical hot-melt extrusion I: Effect of the API particle size, and the co-rotating, twin-screw extruder screw configuration on the API dissolution rate
Meng Li et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Impact of implant composition of twin-screw extruded lipid implants on the release behavior
Marie-Paule Even et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Investigation of an 11 mm diameter twin screw granulator: Screw element performance and in-line monitoring via image analysis
Ridade Sayin et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles
Shaban A. Khaled et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Twin screw granulation - A literature review
Tim Chan Seem et al.
POWDER TECHNOLOGY (2015)
Enhancement of solubility and therapeutic potential of poorly soluble lovastatin by SMEDDS formulation adsorbed on directly compressed spray dried magnesium aluminometasilicate liquid loadable tablets: A study in diet induced hyperlipidemic rabbits
Mohd Javed Qureshi et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Continuous Production of Fenofibrate Solid Lipid Nanoparticles by Hot-Melt Extrusion Technology: a Systematic Study Based on a Quality by Design Approach
Hemlata Patil et al.
AAPS JOURNAL (2015)
Self-microemulsifying drug delivery system (SMEDDS) - challenges and road ahead
Shambhu Dokania et al.
DRUG DELIVERY (2015)
A review on the taste masking of bitter APIs: hot-melt extrusion (HME) evaluation
Mohammed Maniruzzaman et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2014)
Hot-melt extrusion - basic principles and pharmaceutical applications
Bo Lang et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2014)
Fused-filament 3D printing (3DP) for fabrication of tablets
Alvaro Goyanes et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Hot-melt co-extrusion for the production of fixed-dose combination products with a controlled release ethylcellulose matrix core
A. -K. Vynckier et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Desktop 3D printing of controlled release pharmaceutical bilayer tablets
Shaban A. Khaled et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Nano-extrusion: A promising tool for continuous manufacturing of solid nano-formulations
Ramona Baumgartner et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Hot-melt co-extrusion: requirements, challenges and opportunities for pharmaceutical applications
An-Katrien Vynckier et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2014)
Development and evaluation of lafutidine solid dispersion via hot melt extrusion: Investigating drug-polymer miscibility with advanced characterisation
Ritesh Fule et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Real-Time Particle Size Analysis Using Focused Beam Reflectance Measurement as a Process Analytical Technology Tool for a Continuous Granulation-Drying-Milling Process
Vijay Kumar et al.
AAPS PHARMSCITECH (2013)
Granulation Rate Processes in the Kneading Elements of a Twin Screw Granulator
A. S. El Hagrasy et al.
AICHE JOURNAL (2013)
Regime map development for continuous twin screw granulation
Wei-Da Tu et al.
CHEMICAL ENGINEERING SCIENCE (2013)
Model-based analysis of high shear wet granulation from batch to continuous processes in pharmaceutical production - A critical review
Ashish Kumar et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2013)
Co-extrusion as manufacturing technique for multilayer mini-matrices with dual drug release
L. Dierickx et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2013)
Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs
Chau Le-Ngoc Vo et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2013)
PAT tools for the control of co-extrusion implants manufacturing process
Fabrice Krier et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Melt extrusion with poorly soluble drugs
Sejal Shah et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Hot-Melt Granulation in a Twin Screw Extruder: Effects of Processing on Formulations with Caffeine and Ibuprofen
Sharleen Weatherley et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Real-time assessment of critical quality attributes of a continuous granulation process
Margot Fonteyne et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2013)
Comparison of granule properties produced using Twin Screw Extruder and High Shear Mixer: A step towards understanding the mechanism of twin screw wet granulation
Kai T. Lee et al.
POWDER TECHNOLOGY (2013)
In-line Size Monitoring of a Twin Screw Granulation Process Using High-Speed Imaging
A. S. El Hagrasy et al.
JOURNAL OF PHARMACEUTICAL INNOVATION (2013)
Examining the mechanics of granulation with a hot melt binder in a twin-screw extruder
B. Mu et al.
CHEMICAL ENGINEERING SCIENCE (2012)
Mechanochemistry: opportunities for new and cleaner synthesis
Stuart L. James et al.
CHEMICAL SOCIETY REVIEWS (2012)
Prediction of quality attributes of continuously produced granules using complementary pat tools
Margot Fonteyne et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)
Co-extrusion as manufacturing technique for fixed-dose combination mini-matrices
L. Dierickx et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2012)
Melt extrusion: process to product
Michael A. Repka et al.
EXPERT OPINION ON DRUG DELIVERY (2012)
Nanomedicine, nanotechnology in medicine
Patrick Boisseau et al.
COMPTES RENDUS PHYSIQUE (2011)
Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion
Eva Roblegg et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2011)
Pharmaceutical cocrystals: An overview
Ning Qiao et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)
Application of Melt Granulation Technology to Enhance Tabletting Properties of Poorly Compactible High-Dose Drugs
Jay P. Lakshman et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets
Sanjay Garg et al.
ANTIVIRAL RESEARCH (2010)
Understanding the relationship between crystal structure, plasticity and compaction behaviour of theophylline, methyl gallate, and their 1: 1 co-crystal
Sayantan Chattoraj et al.
CRYSTENGCOMM (2010)
Effect of three anthelmentics on disposition kinetics of florfenicol in goats
M. Atef et al.
FOOD AND CHEMICAL TOXICOLOGY (2010)
Improved Lysozyme Stability and Release Properties of Poly(lactide-co-glycolide) Implants Prepared by Hot-Melt Extrusion
Zahra Ghalanbor et al.
PHARMACEUTICAL RESEARCH (2010)
Pharmaceutical Cocrystals and Their Physicochemical Properties
Nate Schultheiss et al.
CRYSTAL GROWTH & DESIGN (2009)
Chronotherapeutic drug delivery for early morning surge in blood pressure: A programmable delivery system
Usha Yogendra Nayak et al.
JOURNAL OF CONTROLLED RELEASE (2009)
Iron Transporters Are Differentially Regulated by Dietary Iron, and Modifications Are Associated with Changes in Manganese Metabolism in Young Pigs
Stephanie L. Hansen et al.
JOURNAL OF NUTRITION (2009)
A new self-emulsifying drug delivery system (SEDDS) for poorly soluble drugs: Characterization, dissolution, in vitro digestion and incorporation into solid pellets
Ahmed Abdalla et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets
Sandra U. Schilling et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)
Impact of Screw Elements on Continuous Granulation With a Twin-Screw Extruder
Dejan Djuric et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2008)
Targeted intestinal delivery of supersaturated itraconazole for improved oral absorption
Dave A. Miller et al.
PHARMACEUTICAL RESEARCH (2008)
Salt formation to improve drug solubility
Abu T. M. Serajuddin
ADVANCED DRUG DELIVERY REVIEWS (2007)
Practical approaches of taste masking technologies in oral solid forms
Dionysios Douroumis
EXPERT OPINION ON DRUG DELIVERY (2007)
Quinine sulphate pellets for flexible pediatric drug dosing: Formulation development and evaluation of taste-masking efficiency using the electronic tongue
P. C. Kayumba et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2007)
Pharmaceutical applications of hot-melt extrusion: Part I
Michael M. Crowley et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2007)
Hot stage extrusion of p-amino salicylic acid with EC using CO2 as a temporary plasticizer
Geert Verreck et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Melt granulation using a twin-screw extruder: A case study
Barbara Van Melkebeke et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Floating hot-melt extruded tablets for gastroretentive controlled drug release system
Mamoru Fukuda et al.
JOURNAL OF CONTROLLED RELEASE (2006)
The effect of pressurized carbon dioxide as a plasticizer and foaming agent on the hot melt extrusion process and extrudate properties of pharmaceutical polymers
Geert Verreck et al.
JOURNAL OF SUPERCRITICAL FLUIDS (2006)
Photopolymerized hydrogel carriers for live vaccine ballistic delivery
RJ Christie et al.
VACCINE (2006)
The effect of pressurized carbon dioxide as a temporary plasticizer and foaming agent on the hot stage extrusion process and extrudate properties of solid dispersions of itraconazole with PVP-VA 64
G Verreck et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Influence of human nail etching for the assessment of topical onychomycosis therapies
MA Repka et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2004)
Sustained release veterinary parenteral products
NJ Medlicott et al.
ADVANCED DRUG DELIVERY REVIEWS (2004)
Oral delivery of medications to companion animals: palatability considerations
AG Thombre
ADVANCED DRUG DELIVERY REVIEWS (2004)
Precision extruding deposition and characterization of cellular poly-epsilon-caprolactone tissue scaffolds
F Wang et al.
RAPID PROTOTYPING JOURNAL (2004)
Taste masking technologies in oral pharmaceuticals: Recent developments and approaches
H Sohi et al.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY (2004)
Influence of methylparaben as a solid-state plasticizer on the physicochemical properties of Eudragit® RS PO hot-melt extrudates
CB Wu et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2003)
Stability of polyethylene oxide in matrix tablets prepared by hot-melt extrusion
MM Crowley et al.
BIOMATERIALS (2002)
Melt extrusion: from process to drug delivery technology
J Breitenbach
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2002)
Effect of supersaturation and crystallization phenomena on the release properties of a controlled release device based on EVA copolymer
JAH van Laarhoven et al.
JOURNAL OF CONTROLLED RELEASE (2002)
Characterization of ibuprofen as a nontraditional plasticizer of ethyl cellulose
C De Brabander et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2002)
In vitro release properties of etonogestrel and ethinyl estradiol from a contraceptive vaginal ring
JAH van Laarhoven et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2002)
The mechanisms of drug release from solid dispersions in water-soluble polymers
DQM Craig
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2002)
Fabrication of porous poly(L-lactic acid) scaffolds for bone tissue engineering via precise extrusion
Z Xiong et al.
SCRIPTA MATERIALIA (2001)
Influence of chlorpheniramine maleate on topical hydroxypropylcellulose films produced by hot-melt extrusion
MA Repka et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2001)
Physical-mechanical, moisture absorption and bioadhesive properties of hydroxypropylcellulose hot-melt extruded films
MA Repka et al.
BIOMATERIALS (2000)
Improving drug solubility for oral delivery using solid dispersions
C Leuner et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2000)
What is the true solubility advantage for amorphous pharmaceuticals?
BC Hancock et al.
PHARMACEUTICAL RESEARCH (2000)
Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans
WL Chiou et al.
PHARMACEUTICAL RESEARCH (2000)