Construction of hypercrosslinked polymers for high-performance solid phase microextraction of phthalate esters from water samples

Design and synthesis of novel coatings for solid phase microextraction (SPME) is urgently needed for sample pretreatment. In this study, three hypercrosslinked polymers (HCPs) were constructed by the facile Friedel-Crafts alkylation reactions between tetraphenylethylene (TPE) and 1,4-bis(chloromethyl)benzene (BCMB), 4,4'-bis(chloromethyl)-1,1'-biphenyl (BCMBP), and cyanuric chloride (CC), respectively. The newly-synthesized HCPs were employed as SPME coatings for the extraction of phthalate esters (PAEs). Various parameters influencing the SPME efficiencies, including extraction time and temperature, ionic strength, stirring rate, desorption temperature and time were optimized. Under the optimal conditions, low limits of detection (0.003-0.033 mu g L-1), wide linearity (0.01-10 mu g L-1) and good repeatability (4.1-9.3%) were achieved. The HCPs-based SPME method was successfully applied for the determination of eight PAEs in environmental water and bottled water samples with recoveries from 75.3% to 116%. This method provides a good alternative for monitoring trace level of PAEs in water samples. (C) 2021 Elsevier B.V. All rights reserved.

Automated summary

Novel coatings for the extraction of phthalate esters (PAEs) were developed using three hypercrosslinked polymers (HCPs) constructed in this study. The optimized SPME method showed low detection limits and good repeatability for the determination of eight PAEs in water samples, with satisfactory recoveries achieved. This approach provides a promising alternative for monitoring trace levels of PAEs in water samples.