Related references
Note: Only part of the references are listed.De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein
Sebastian Pomplun et al.
ACS CENTRAL SCIENCE (2021)
Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides
Sebastian Pomplun
RSC MEDICINAL CHEMISTRY (2021)
Peptide-Based Vaccines: Current Progress and Future Challenges
Ryan J. Malonis et al.
CHEMICAL REVIEWS (2020)
The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus
Calvin J. Gordon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS
Yushun Wan et al.
JOURNAL OF VIROLOGY (2020)
A new coronavirus associated with human respiratory disease in China
Fan Wu et al.
NATURE (2020)
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Renhong Yan et al.
SCIENCE (2020)
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp et al.
SCIENCE (2020)
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
Michael Letko et al.
NATURE MICROBIOLOGY (2020)
Computational Design of ACE2-Based Peptide Inhibitors of SARS-CoV-2
Yanxiao Han et al.
ACS NANO (2020)
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Qihui Wang et al.
CELL (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
Shuai Xia et al.
CELL RESEARCH (2020)
Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan
Jasper Fuk-Woo Chan et al.
EMERGING MICROBES & INFECTIONS (2020)
A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction
Jeongmin Han et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Templated folding of intrinsically disordered proteins
Angelo Toto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing Study
Junmei Wang
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2020)
Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations
Angelo Spinello et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2020)
Comparing the Binding Interactions in the Receptor Binding Domains of SARS-CoV-2 and SARS-CoV
Muhamed Amin et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2020)
Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps
Jonathan Whisenant et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
A human monoclonal antibody blocking SARS-CoV-2 infection
Chunyan Wang et al.
NATURE COMMUNICATIONS (2020)
Mechanism of Coupled Folding-upon-Binding of an Intrinsically Disordered Protein
Paul Robustelli et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
Cynthia Liu et al.
ACS CENTRAL SCIENCE (2020)
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Jun Lan et al.
NATURE (2020)
Structural basis of receptor recognition by SARS-CoV-2
Jian Shang et al.
NATURE (2020)
Nanotechnology for COVID-19: Therapeutics and Vaccine Research
Gaurav Chauhan et al.
ACS NANO (2020)
Enhanced Binding of SARS-CoV-2 Spike Protein to Receptor by Distal Polybasic Cleavage Sites
Baofu Qiao et al.
ACS NANO (2020)
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Carsten Weiss et al.
ACS NANO (2020)
De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2
Xiaoqiang Huang et al.
Aging-US (2020)
Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein
Yanling Song et al.
ANALYTICAL CHEMISTRY (2020)
Interaction of the spike protein RBD from SARS-CoV-2 with ACE2: Similarity with SARS-CoV, hot-spot analysis and effect of the receptor polymorphism
Houcemeddine Othman et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
Christopher O. Barnes et al.
CELL (2020)
Insulin Dissociates by Diverse Mechanisms of Coupled Unfolding and Unbinding
Adam Antoszewski et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2020)
Dynamic Asymmetry Exposes 2019-nCoV Prefusion Spike
Susmita Roy et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2020)
Protein energy landscape exploration with structure-based models
Sridhar Neelamraju et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2020)
Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and interactions
Yingjie Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
Kui K. Chan et al.
SCIENCE (2020)
Disordered proteins follow diverse transition paths as they fold and bind to a partner
Jae-Yeol Kim et al.
SCIENCE (2020)
On the interactions of the receptor-binding domain of SARS-CoV-1 and SARS-CoV-2 spike proteins with monoclonal antibodies and the receptor ACE2
Carolina Correa Giron et al.
VIRUS RESEARCH (2020)
Identification of a Potential Peptide Inhibitor of SARS-CoV-2 Targeting its Entry into the Host Cells
Mirza S. Baig et al.
DRUGS IN R&D (2020)
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Anum Glasgow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Longxing Cao et al.
SCIENCE (2020)
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
Subodh Kumar Samrat et al.
VIRUS RESEARCH (2020)
Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
Wayne Vuong et al.
NATURE COMMUNICATIONS (2020)
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein (vol 180, 281.e1, 2020)
Alexandra C. Walls et al.
CELL (2020)
Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin
Courtney J. Mycroft-West et al.
THROMBOSIS AND HAEMOSTASIS (2020)
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2
Thomas W. Linsky et al.
SCIENCE (2020)
The Potential of Antimicrobial Peptides as an Antiviral Therapy against COVID-19
Sherif Elnagdy et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2020)
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
Alexandra C. Walls et al.
CELL (2019)
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors
Robert N. Kirchdoerfer et al.
NATURE COMMUNICATIONS (2019)
Explicit Characterization of the Free Energy Landscape of pKID-KIX Coupled Folding and Binding
Song-Ho Chong et al.
ACS CENTRAL SCIENCE (2019)
Anabel: An Online Tool for the Real-Time Kinetic Analysis of Binding Events
Stefan D. Kraemer et al.
BIOINFORMATICS AND BIOLOGY INSIGHTS (2019)
How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein?
Daniela Bonetti et al.
BIOPHYSICAL JOURNAL (2018)
Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins
Michael D. Crabtree et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Identifying Conformational-Selection and Induced-Fit Aspects in the Binding-Induced Folding of PMI from Markov State Modeling of Atomistic Simulations
Fabian Paul et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2018)
Dimerization of Coronavirus nsp9 with Diverse Modes Enhances Its Nucleic Acid Binding Affinity
Zhe Zeng et al.
JOURNAL OF VIROLOGY (2018)
GA-Hecate antiviral properties on HCV whole cycle represent a new antiviral class and open the door for the development of broad spectrum antivirals
Mariana Nogueira Batista et al.
SCIENTIFIC REPORTS (2018)
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
Robert N. Kirchdoerfer et al.
SCIENTIFIC REPORTS (2018)
Transition path times of coupled folding and binding reveal the formation of an encounter complex
Flurin Sturzenegger et al.
NATURE COMMUNICATIONS (2018)
Interplay between the folding mechanism and binding modes in folding coupled to binding processes
Rajendra Sharma et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2017)
Binding mechanism and dynamic conformational change of C subunit of PKA with different pathways
Wen-Ting Chu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Yuan Yuan et al.
NATURE COMMUNICATIONS (2017)
Native Hydrophobic Binding Interactions at the Transition State for Association between the TAZ1 Domain of CBP and the Disordered TAD-STAT2 Are Not a Requirement
Ida Lindstrom et al.
BIOCHEMISTRY (2017)
Dissecting mechanism of coupled folding and binding of an intrinsically disordered protein by chemical synthesis of conformationally constrained analogues
Boris Schmidtgall et al.
CHEMICAL COMMUNICATIONS (2017)
Insights into Protein-Ligand Interactions: Mechanisms, Models, and Methods
Xing Du et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Protein Frustratometer 2: a tool to localize energetic frustration in protein molecules, now with electrostatics
R. Gonzalo Parra et al.
NUCLEIC ACIDS RESEARCH (2016)
SMOG 2: A Versatile Software Package for Generating Structure-Based Models
Jeffrey K. Noel et al.
PLOS COMPUTATIONAL BIOLOGY (2016)
Neither Two-State nor Three-State: Dimerization of Lambda Cro Repressor
John Yao et al.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2015)
Visualizing the Molecular Recognition Trajectory of an Intrinsically Disordered Protein Using Multinuclear Relaxation Dispersion NMR
Robert Schneider et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding
Munehito Arai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond
Guangwen Lu et al.
TRENDS IN MICROBIOLOGY (2015)
Connecting Thermal and Mechanical Protein (Un)folding Landscapes
Li Sun et al.
BIOPHYSICAL JOURNAL (2014)
Deciphering key features in protein structures with the new ENDscript server
Xavier Robert et al.
NUCLEIC ACIDS RESEARCH (2014)
Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein
Joseph M. Rogers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Proteolytic activation of the SARS-coronavirus spike protein: Cutting enzymes at the cutting edge of antiviral research
Graham Simmons et al.
ANTIVIRAL RESEARCH (2013)
Kinetics and Energetics of Biomolecular Folding and Binding
Christopher A. Pierse et al.
BIOPHYSICAL JOURNAL (2013)
Remarkably Fast Coupled Folding and Binding of the Intrinsically Disordered Transactivation Domain of cMyb to CBP KIX
Sarah L. Shammas et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not 'Diffusion-Limited'
Joseph M. Rogers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system
Rajanish Giri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Quantifying the topography of the intrinsic energy landscape of flexible biomolecular recognition
Xiakun Chu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Dynamics and mechanisms of coupled protein folding and binding reactions
Thomas Kiefhaber et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
Protein frustratometer: a tool to localize energetic frustration in protein molecules
Michael Jenik et al.
NUCLEIC ACIDS RESEARCH (2012)
The Unique Cysteine Knot Regulates the Pleotropic Hormone Leptin
Ellinor Haglund et al.
PLOS ONE (2012)
Topography of funneled landscapes determines the thermodynamics and kinetics of protein folding
Jin Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Biomolecular dynamics: order-disorder transitions and energy landscapes
Paul C. Whitford et al.
REPORTS ON PROGRESS IN PHYSICS (2012)
The Protein-Folding Problem, 50 Years On
Ken A. Dill et al.
SCIENCE (2012)
Interdomain communication revealed in the diabetes drug target mitoNEET
Elizabeth L. Baxter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
Annett Bachmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Capillarity theory for the fly-casting mechanism
Emmanuel Trizac et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Principles of protein folding - A perspective from simple exact models
Ken A. Dill et al.
PROTEIN SCIENCE (2010)
Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
Peter Csermely et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Linking folding and binding
Peter E. Wright et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain
John E. Pak et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Direct Observation of the Dynamic Process Underlying Allosteric Signal Transmission
Sven Brueschweiler et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX
Marzena Pazgiera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites
Sandrine Belouzard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An all-atom structure-based potential for proteins: Bridging minimal models with all-atom empirical forcefields
Paul C. Whitford et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)
Transition state for protein-DNA recognition
Diego U. Ferreiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Inference of macromolecular assemblies from crystalline state
Evgeny Krissinel et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding
Jorge Chahine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanism of coupled folding and binding of an intrinsically disordered protein
Kenji Sugase et al.
NATURE (2007)
Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R
William C. Hwang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A free-energy landscape picture and Landau theory for the dynamics of disordered materials
Mohammad Reza H. Javaheri et al.
JOURNAL OF CHEMICAL PHYSICS (2006)
Single-molecule dynamics reveals cooperative binding-folding in protein recognition
Jin Wang et al.
PLOS COMPUTATIONAL BIOLOGY (2006)
Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor
Dong P. Han et al.
VIROLOGY (2006)
Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody
Ponraj Prabakaran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
P versus Q:: Structural reaction coordinates capture protein folding on smooth landscapes
SS Cho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
GROMACS: Fast, flexible, and free
D Van der Spoel et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor
F Li et al.
SCIENCE (2005)
The experimental survey of protein-folding energy landscapes
Mikael Oliveberg et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2005)
The FoldX web server: an online force field
J Schymkowitz et al.
NUCLEIC ACIDS RESEARCH (2005)
A survey of flexible protein binding mechanisms and their transition states using native topology based energy landscapes
Y Levy et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Protein topology determines binding mechanism
Y Levy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
The role of sidechain packing and native contact interactions in folding:: Discontinuous molecular dynamics folding simulations of an all-atom G(o)over-bar model of fragment B of Staphylococcal protein A
A Linhananta et al.
JOURNAL OF CHEMICAL PHYSICS (2002)
Speeding molecular recognition by using the folding funnel: The fly-casting mechanism
BA Shoemaker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Topological and energetic factors: What determines the structural details of the transition state ensemble and en-route intermediates for protein folding? An investigation for small globular proteins
C Clementi et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Share Paper
