4.2 Review

Post-translational modification enzymes as key regulators of ciliary protein trafficking

Related references

Note: Only part of the references are listed.
Article Anatomy & Morphology

PhosphositeT674Amutation in kinesin family member3Afails to reproduce tissue and ciliary defects characteristic ofCILK1loss of function

Casey D. Gailey et al.

Summary: Mutation of phosphorylation site Thr674 in mouse Kif3a did not reproduce the severe developmental defects caused by Cilk1 loss of function, indicating that phosphorylation of KIF3A-Thr672 by CILK1 is not essential for tissue development and other substrates may be involved in CILK1 ciliopathies.

DEVELOPMENTAL DYNAMICS (2021)

Article Biochemistry & Molecular Biology

Regulation of flagellar assembly and length in Chlamydomonas by LF4, a MAPK-related kinase

Yingrui Wang et al.

FASEB JOURNAL (2019)

Review Urology & Nephrology

Cellular signalling by primary cilia in development, organ function and disease

Zeinab Anvarian et al.

NATURE REVIEWS NEPHROLOGY (2019)

Article Multidisciplinary Sciences

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

Michaela Kunova Bosakova et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Genetics & Heredity

LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena

Yu-Yang Jiang et al.

PLOS GENETICS (2019)

Review Biochemistry & Molecular Biology

Ciliogenesis associated kinase 1: targets and functions in various organ systems

Zheng Fu et al.

FEBS LETTERS (2019)

Article Biochemistry & Molecular Biology

Cul3-Klhl18 ubiquitin ligase modulates rod transducin translocation during light-dark adaptation

Taro Chaya et al.

EMBO JOURNAL (2019)

Review Biochemistry & Molecular Biology

Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors

Kazuhisa Nakayama et al.

JOURNAL OF BIOCHEMISTRY (2018)

Review Cell Biology

The molecular machines that traffic signaling receptors into and out of cilia

Maxence V. Nachury

CURRENT OPINION IN CELL BIOLOGY (2018)

Article Developmental Biology

Enriched expression of the ciliopathy gene Ick in cell proliferating regions of adult mice

Ryotaro Tsutsumi et al.

GENE EXPRESSION PATTERNS (2018)

Article Medicine, General & Internal

Variant Intestinal-Cell Kinase in Juvenile Myoclonic Epilepsy

J. N. Bailey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Medicine, General & Internal

Age-related macular degeneration

Paul Mitchell et al.

LANCET (2018)

Review Biochemistry & Molecular Biology

Trafficking of ciliary membrane proteins by the intraflagellar transport/BBSome machinery

Jenna L. Wingfield et al.

MICROTUBULES AND CENTROSOMES (2018)

Article Cell Biology

Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition

Francesc R. Garcia-Gonzalo et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)

Article Biochemistry & Molecular Biology

The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment

Christin Hanke-Gogokhia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2017)

Review Cell Biology

Genes and molecular pathways underpinning ciliopathies

Jeremy F. Reiter et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Cell Biology

The Cilium: Cellular Antenna and Central Processing Unit

Jarema J. Malicki et al.

TRENDS IN CELL BIOLOGY (2017)

Article Biology

Dynamics of the IFT machinery at the ciliary tip

Alexander Chien et al.

ELIFE (2017)

Article Biochemistry & Molecular Biology

Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision

Siew Cheng Phua et al.

Article Biochemistry & Molecular Biology

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome

S. Paige Taylor et al.

HUMAN MOLECULAR GENETICS (2016)

Article Biochemistry & Molecular Biology

Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors

Christin Hanke-Gogokhia et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Ophthalmology

HISTORY OF SUNLIGHT EXPOSURE IS A RISK FACTOR FOR AGE-RELATED MACULAR DEGENERATION

Tina Schick et al.

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2016)

Article Biochemistry & Molecular Biology

Mistrafficking of prenylated proteins causes retinitis pigmentosa 2

Houbin Zhang et al.

FASEB JOURNAL (2015)

Review Biochemistry & Molecular Biology

IFT-Cargo Interactions and Protein Transport in Cilia

Karl F. Lechtreck

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Article Biochemistry & Molecular Biology

Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity

Sophie Thomas et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2015)

Article Biochemistry & Molecular Biology

ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport

Taro Chaya et al.

EMBO JOURNAL (2014)

Article Multidisciplinary Sciences

Intestinal cell kinase, a protein associated with endocrine-cerebro-osteodysplasia syndrome, is a key regulator of cilia length and Hedgehog signaling

Heejung Moon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells

Anurima Majumder et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Genetics & Heredity

Update on the Kelch-like (KLHL) gene family

Bajinder S. Dhanoa et al.

HUMAN GENOMICS (2013)

Article Biochemistry & Molecular Biology

Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119

Shehab A. Ismail et al.

EMBO JOURNAL (2012)

Article Cell Biology

The BBSome controls IFT assembly and turnaround in cilia

Qing Wei et al.

NATURE CELL BIOLOGY (2012)

Article Biochemistry & Molecular Biology

Clinical and Rehabilitative Management of Retinitis Pigmentosa:Up-to-Date

Katia De Nadai et al.

CURRENT GENOMICS (2011)

Article Cell Biology

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

Kevin J. Wright et al.

GENES & DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

Interaction of Transducin with Uncoordinated 119 Protein (UNC119) IMPLICATIONS FOR THE MODEL OF TRANSDUCIN TRAFFICKING IN ROD PHOTORECEPTORS

Kota N. Gopalakrishna et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Neurosciences

Diffusion and light-dependent compartmentalization of transducin

Vasily Kerov et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

Shehab A. Ismail et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Neurosciences

UNC119 is required for G protein trafficking in sensory neurons

Houbin Zhang et al.

NATURE NEUROSCIENCE (2011)

Review Cell Biology

Ciliogenesis: building the cell's antenna

Hiroaki Ishikawa et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa

Budd A. Tucker et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Biotechnology & Applied Microbiology

The cullin protein family

Antonio Sarikas et al.

GENOME BIOLOGY (2011)

Article Ophthalmology

Moderate Light-Induced Degeneration of Rod Photoreceptors with Delayed Transducin Translocation in shaker1 Mice

You-Wei Peng et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Biochemistry & Molecular Biology

The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium

R. Jane Evans et al.

HUMAN MOLECULAR GENETICS (2010)

Article Multidisciplinary Sciences

Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival

Yoshihiro Omori et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biochemistry & Molecular Biology

Centrioles, Centrosomes, and Cilia in Health and Disease

Erich A. Nigg et al.

Review Biochemistry & Molecular Biology

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

Jantje M. Gerdes et al.

Article Multidisciplinary Sciences

FGF signalling during embryo development regulates cilia length in diverse epithelia

Judith M. Neugebauer et al.

NATURE (2009)

Article Multidisciplinary Sciences

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy et al.

NATURE (2009)

Article Genetics & Heredity

Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome

Vincent Cantagrel et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2008)

Article Biochemistry & Molecular Biology

Light-dependent CK2-mediated phosphorylation of centrins regulates complex formation with visual G-protein

Philipp Trojan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2008)

Article Biochemistry & Molecular Biology

The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3

Stefan Veltel et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)

Review Cell Biology

Mechanisms of disease - When cilia go bad: cilia defects and ciliopathies

Manfred Fliegauf et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Deletion of PrBP/δ impedes transport of GRK1 and PDE6 catalytic subunits to photoreceptor outer segments

H. Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Mutation of the MAP kinase DYF-5 affects docking and undocking of kinesin-2 motors and reduces their speed in the cilia of Caenorhabditis elegans

Jan Burghoorn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Cell Biology

A CDK-related kinase regulates the length and assembly of flagella in Chlamydomonas

Lai-Wa Tam et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

LmxMPK9, a mitogen-activated protein kinase homologue affects flagellar length in Leishmania mexicana

F Bengs et al.

MOLECULAR MICROBIOLOGY (2005)

Review Cell Biology

Function and regulation of Cullin-RING ubiquitin ligases

MD Petroski et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Ophthalmology

An atypical phenotype of macular and peripapillary retinal atrophy caused by a mutation in the RP2 gene

SS Dandekar et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2004)

Review Biochemistry & Molecular Biology

Nedd8 on cullin: building an expressway to protein destruction

ZQ Pan et al.

ONCOGENE (2004)

Article Multidisciplinary Sciences

The protein kinase complement of the human genome

G Manning et al.

SCIENCE (2002)

Review Cell Biology

Intraflagellar transport

JL Rosenbaum et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Biochemistry & Molecular Biology

A testicular germ cell-associated serine-threonine kinase, MAK, is dispensable for sperm formation

Y Shinkai et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)