Hydroxynitrile Glucosides: Bioactive Constituent Recovery from the Oil Residue of Prinsepia utilis

The seed oil of Prinsepia utilis is extensively used as an edible oil by the nationalities of Naxi, Tibetan, and Mosuo in China, which is particularly good for beauty care and has a health protection function. A large amount of industrial waste is thrown away during the production process of seed oil. Therefore, to recover bioactive compounds from the oil residue of P. utilis is environmentally friendly and economically important. For this purpose, the chemical constituents of the P. utilis oil residue were investigated in our research, and five new compounds, prinsepicyanosides F-I (1-4) and prinamoside A (5), together with 16 known compounds (6-21) were isolated. The structures of the new compounds (1-5) were unambiguously confirmed by extensive spectroscopic techniques. Preliminary in vitro pharmacological studies showed that the hydroxynitrile glucosides (3, 9, and 10) exhibited weak a-glucosidase inhibitory activity. To a certain extent, our research provides some evidence for the pharmacological function of gamma-hydroxynitrile glucosides and proposes new ideas for recycling of the oil residue of P. utilis.

Automated summary

The seed oil of Prinsepia utilis is widely used as an edible oil in China by the Naxi, Tibetan, and Mosuo nationalities, known for its beauty care and health protection function. Extracting bioactive compounds from the oil residue of P. utilis is both environmentally friendly and economically important. This study isolated new compounds and provided evidence for the pharmacological function of gamma-hydroxynitrile glucosides.