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FRONTIERS IN AGING NEUROSCIENCE (2014)
Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model
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MOLECULAR BRAIN (2014)
Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis
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PLOS MEDICINE (2014)
Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model
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AGING CELL (2013)
Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress
Jing Zheng et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
Principles in Redox Signaling: From Chemistry to Functional Significance
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ANTIOXIDANTS & REDOX SIGNALING (2013)
Thiol-Dependent Recovery of Catalytic Activity from Oxidized Protein Tyrosine Phosphatases
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BIOCHEMISTRY (2013)
Traumatic Scratch Injury in Astrocytes Triggers Calcium Influx to Activate the JNK/c-Jun/AP-1 Pathway and Switch on GFAP Expression
Kai Gao et al.
GLIA (2013)
Supplementation of Nitric Oxide Attenuates AβPP and BACE1 Protein in Cerebral Microcirculation of eNOS-Deficient Mice
Susan A. Austin et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Intranasal Insulin Ameliorates Tau Hyperphosphorylation in a Rat Model of Type 2 Diabetes
Yan Yang et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
The Redox Biochemistry of Protein Sulfenylation and Sulfinylation
Mauro Lo Conte et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Antioxidant effect of Spirulina (Arthrospira) maxima in a neurotoxic model caused by 6-OHDA in the rat striatum
J. C. Tobon-Velasco et al.
JOURNAL OF NEURAL TRANSMISSION (2013)
Amyloid-β1-42 Slows Clearance of Synaptically Released Glutamate by Mislocalizing Astrocytic GLT-1
Annalisa Scimemi et al.
JOURNAL OF NEUROSCIENCE (2013)
Current evidence for the clinical use of long-chain polyunsaturated N-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease
P. A. Dacks et al.
JOURNAL OF NUTRITION HEALTH & AGING (2013)
(-)-Epigallocatechin-3-gallate alleviates spatial memory impairment in APP/PS1 mice by restoring IRS-1 signaling defects in the hippocampus
Ning Jia et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2013)
Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons
Tao Liu et al.
MOLECULAR PAIN (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms
Daniela Giuliani et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2013)
Antidiabetic potential of phycocyanin: Effects on KKAy mice
Yu Ou et al.
PHARMACEUTICAL BIOLOGY (2013)
Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats
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TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death
A. M. Brennan-Minnella et al.
CELL DEATH & DISEASE (2013)
Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease
B. Parajuli et al.
CELL DEATH & DISEASE (2013)
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Zbynek Strasky et al.
FOOD & FUNCTION (2013)
Age-related loss of nitric oxide synthase in skeletal muscle causes reductions in calpain S-nitrosylation that increase myofibril degradation and sarcopenia
Giuseppina Samengo et al.
AGING CELL (2012)
Selenium and cognitive impairment: A brief-review based on results from the EVA study
Claudine Berr et al.
BIOFACTORS (2012)
Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling
Zhen Wang et al.
BRITISH JOURNAL OF NUTRITION (2012)
Cell surface turnover of the glutamate transporter GLT-1 is mediated by ubiquitination/deubiquitination
Jaime Martinez-Villarreal et al.
GLIA (2012)
Protein Kinase C (PKC)-promoted Endocytosis of Glutamate Transporter GLT-1 Requires Ubiquitin Ligase Nedd4-2-dependent Ubiquitination but Not Phosphorylation
Noemi Garcia-Tardon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
TLR2 Is a Primary Receptor for Alzheimer's Amyloid β Peptide To Trigger Neuroinflammatory Activation
Shirong Liu et al.
JOURNAL OF IMMUNOLOGY (2012)
Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway
Ana Patricia Simoes et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Upregulation of the E3 ligase NEDD4-1 by Oxidative Stress Degrades IGF-1 Receptor Protein in Neurodegeneration
Young-Don Kwak et al.
JOURNAL OF NEUROSCIENCE (2012)
Self-Reported Dietary Intake of Potassium, Calcium, and Magnesium and Risk of Dementia in the Japanese: The Hisayama Study
Mio Ozawa et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2012)
The natural carotenoid astaxanthin, a PPAR-α agonist and PPAR-γ antagonist, reduces hepatic lipid accumulation by rewiring the transcriptome in lipid-loaded hepatocytes
Yaoyao Jia et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2012)
Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model
Siva Sundara Kumar Durairajan et al.
NEUROBIOLOGY OF AGING (2012)
A Spirulina-Enhanced Diet Provides Neuroprotection in an α-Synuclein Model of Parkinson's Disease
Mibel M. Pabon et al.
PLOS ONE (2012)
Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation
Ciro Coletta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease
Timo Grimmer et al.
SCIENTIFIC WORLD JOURNAL (2012)
Proteolytic Degradation of Amyloid β-Protein
Takaomi Saido et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Amyloid Beta Induces Oxidative Stress-Mediated Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy
Anna Carrano et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Insights into modulation of calcium signaling by magnesium in calmodulin, troponin C and related EF-hand proteins
Zenon Grabarek
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Involvement of IRE1α signaling in the hippocampus in patients with mesial temporal lobe epilepsy
Gonglu Liu et al.
BRAIN RESEARCH BULLETIN (2011)
C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils
Giselle Penton-Rol et al.
BRAIN RESEARCH BULLETIN (2011)
GLT-1 Loss Accelerates Cognitive Deficit Onset in an Alzheimer's Disease Animal Model
Paramita Mookherjee et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
PPAR gamma Co-Activator-1 alpha (PGC-1 alpha) Reduces Amyloid-beta Generation Through a PPAR gamma-Dependent Mechanism
Loukia Katsouri et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Increased CSF-BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease
Michael Ewers et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Amyloid-beta(42) Activates the Expression of BACE1 Through the JNK Pathway
Michela Guglielmotto et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal β-Catenin Pathway Function in an Alzheimer's Disease Model
Masashi Kitazawa et al.
JOURNAL OF IMMUNOLOGY (2011)
Soluble Aβ Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors
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JOURNAL OF NEUROSCIENCE (2011)
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
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KIDNEY INTERNATIONAL (2011)
Differential regulation of BACE1 expression by oxidative and nitrosative signals
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MOLECULAR NEURODEGENERATION (2011)
Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors
Raik Roenicke et al.
NEUROBIOLOGY OF AGING (2011)
Effects of Selenium Supplements on Cancer Prevention: Meta-Analysis of Randomized Controlled Trials
Eun-Hyun Lee et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2011)
Hypoxia-Induced Down-Regulation of Neprilysin by Histone Modification in Mouse Primary Cortical and Hippocampal Neurons
Zheng Wang et al.
PLOS ONE (2011)
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β
Laibaik Park et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Kaempferol modulates pro-inflammatory NF-κB activation by suppressing advanced glycation endproducts-induced NADPH oxidase
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AGE (2010)
FoxM1B Regulates NEDD4-1 Expression, Leading to Cellular Transformation and Full Malignant Phenotype in Immortalized Human Astrocytes
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CANCER RESEARCH (2010)
N-Acetylcysteine Prevents 4-Hydroxynonenal- and Amyloid-beta-Induced Modification and Inactivation of Neprilysin in SH-SY5Y Cells
Rui Wang et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Inhibition of Calcineurin-mediated Endocytosis and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors Prevents Amyloid β Oligomer-induced Synaptic Disruption
Wei-Qin Zhao et al.
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Phosphopeptide Screen Uncovers Novel Phosphorylation Sites of Nedd4-2 That Potentiate Its Inhibition of the Epithelial Na+ Channel
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Neuroprotective effect of Spirulina in cerebral ischemia-reperfusion injury in rats
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Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses
Peng Xia et al.
JOURNAL OF NEUROSCIENCE (2010)
Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress
Alexander M. Wolf et al.
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Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo
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Acute p38-mediated inhibition of NMDA-induced outward currents in hippocampal CA1 neurons by interleukin-1 beta
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Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Alcohol Consumption as a Risk Factor for Dementia and Cognitive Decline: Meta-Analysis of Prospective Studies
Kaarin J. Anstey et al.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2009)
Natriuretic Peptides/cGMP/cGMP-Dependent Protein Kinase Cascades Promote Muscle Mitochondrial Biogenesis and Prevent Obesity
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DIABETES (2009)
FoxM1, a critical regulator of oxidative stress during oncogenesis
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EMBO JOURNAL (2009)
Effects of HNE-modification induced by Aβ on neprilysin expression and activity in SH-SY5Y cells
Rui Wang et al.
JOURNAL OF NEUROCHEMISTRY (2009)
β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin
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JOURNAL OF NEUROSCIENCE (2009)
Neprilysin: An enzyme candidate to slow the progression of Alzheimer's disease
Salim S. El-Amouri et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Inhibition of NMDA-induced outward currents by interleukin-1β in hippocampal neurons
Ruoyu Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Mechanism of 4-HNE mediated inhibition of hDDAH-1: Implications in no regulation
Scott P. Forbes et al.
BIOCHEMISTRY (2008)
CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages
Xingguang Liu et al.
BLOOD (2008)
Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice
Brian Spencer et al.
BMC NEUROSCIENCE (2008)
Antihypertensive effect of biotin in stroke-prone spontaneously hypertensive rats
Mari Watanabe-Kamiyama et al.
BRITISH JOURNAL OF NUTRITION (2008)
Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease
Soenke Arlt et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2008)
N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility
Seetal Dodd et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2008)
Fibrillar Amyloid-β Peptides Activate Microglia via TLR2: Implications for Alzheimer's Disease
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Postsynaptic Action Potentials Are Required for Nitric-Oxide-Dependent Long-Term Potentiation in CA1 Neurons of Adult GluR1 Knock-Out and Wild-Type Mice
Keith G. Phillips et al.
JOURNAL OF NEUROSCIENCE (2008)
Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1
Amanda L. Sheldon et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles
Hua Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Clinical potential of Spirulina as a source of phycocyanobilin
Mark F. McCarty
JOURNAL OF MEDICINAL FOOD (2007)
Phycobiliprotein C-phycocyanin from Spirulina platensis is powerfully responsible for reducing oxidative stress and NADPH oxidafse expression induced by an atherogenic diet in hamsters
Jerome Riss et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2007)
N-Acetylcysteine -: a safe antidote for cysteine/glutathione deficiency
Kondala R. Atkuri et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
Sterol regulatory element binding proteins downregulate LDL receptor-related protein (LRP1) expression and LRP1-mediated aggregated LDL uptake by human macrophages
Vicenta Llorente-Cortes et al.
CARDIOVASCULAR RESEARCH (2007)
Hypoxia-inducible factor 1α (HIF-1α)-mediated hypoxia increases BACE1 expression and β-amyloid generation
Xian Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Role of the blood-brain barrier in the pathogenesis of Alzheimer's disease
Rashid Deane et al.
CURRENT ALZHEIMER RESEARCH (2007)
Carbon monoxide and bilirubin from heme oxygenase-1 suppresses reactive oxygen species generation and plasminogen activator inhibitor-1 induction
Hayato Matsumoto et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2006)
RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease
John E. Donahue et al.
ACTA NEUROPATHOLOGICA (2006)
Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
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JOURNAL OF CLINICAL INVESTIGATION (2006)
Nitric oxide regulates mitochondrial oxidative stress protection via the transcriptional coactivator PGC-1α
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FASEB JOURNAL (2006)
International studies in dementia with particular emphasis on populations of African origin
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ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2006)
Sterol regulatory element-binding protein-2 negatively regulates low density lipoprotein receptor-related protein transcription
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JOURNAL OF MOLECULAR BIOLOGY (2006)
CGMP may have trophic effects on beta cell function comparable to those of cAMP, implying a role for high-dose biotin in prevention/treatment of diabetes
MF McCarty
MEDICAL HYPOTHESES (2006)
Oxidative stress and ageing:: is ageing a cysteine deficiency syndrome?
W Dröge
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2005)
Bilirubin decreases NOS2 expression via inhibition of NAD(P)H oxidase:: implications for protection against endotoxic shock in rats
S Lanone et al.
FASEB JOURNAL (2005)
Nrf2 as a novel molecular target for chemoprevention
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CANCER LETTERS (2005)
Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway - Direct cross-talk between phase I and II drug-metabolizing enzymes
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging
DS Wang et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
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Glutaredoxin:: Role in reversible protein S-glutathionylation and regulation of redox signal transduction and protein translocation
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ANTIOXIDANTS & REDOX SIGNALING (2005)
NADPH oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid β peptide
L Park et al.
JOURNAL OF NEUROSCIENCE (2005)
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
HIF-1: the knowns and unknowns of hypoxia sensing
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ACTA BIOCHIMICA POLONICA (2004)
Oxidized neprilysin in aging and Alzheimer's disease brains
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial
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Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice
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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
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NATURE MEDICINE (2003)
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
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β-secretase protein and activity are increased in the neocortex in Alzheimer disease
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ARCHIVES OF NEUROLOGY (2002)
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NATURE (2000)
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