4.7 Review

How Cells Communicate with Each Other in the Tumor Microenvironment: Suggestions to Design Novel Therapeutic Strategies in Cancer Disease

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications

Max Zachrisson Totland et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Article Biochemistry & Molecular Biology

Blood contains circulating cell-free respiratory competent mitochondria

Zahra Al Amir Dache et al.

FASEB JOURNAL (2020)

Review Oncology

The Role of MSCs in the Tumor Microenvironment and Tumor Progression

Sung Yong Ahn

ANTICANCER RESEARCH (2020)

Review Cell Biology

Purinergic Signaling in the Hallmarks of Cancer

Anai del Rocio Campos-Contreras et al.

CELLS (2020)

Review Oncology

The pathological features of regulated necrosis

Wulf Tonnus et al.

JOURNAL OF PATHOLOGY (2019)

Article Biology

Cooperativity between stromal cytokines drives the invasive migration of human breast cancer cells

Yair Elisha et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2019)

Article Biochemistry & Molecular Biology

Effect of gap junction-mediated intercellular communication on TGF-β induced epithelial-to-mesenchymal transition2

Shuhei Fukuda et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Immunology

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells

Claudia Sorrentino et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Biochemistry & Molecular Biology

Connexins and Pannexins: Important Players in Tumorigenesis, Metastasis and Potential Therapeutics

Sheila V. Graham et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Oncology

Cancer Connectors: Connexins, Gap Junctions, and Communication

Maksim Sinyuk et al.

FRONTIERS IN ONCOLOGY (2018)

Review Immunology

The two faces of pannexins: new roles in inflammation and repair

Helen P. Makarenkova et al.

JOURNAL OF INFLAMMATION RESEARCH (2018)

Review Biochemistry & Molecular Biology

Extracellular purines, purinergic receptors and tumor growth

F. Di Virgilio et al.

ONCOGENE (2017)

Review Oncology

Targeting adenosine in cancer immunotherapy: a review of recent progress

Theresa L. Whiteside

EXPERT REVIEW OF ANTICANCER THERAPY (2017)

Article Biochemistry & Molecular Biology

Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes

Katarzyna Parzych et al.

FASEB JOURNAL (2017)

Article Neurosciences

The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

Farraj Albalawi et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

A quantized mechanism for activation of pannexin channels

Yu-Hsin Chiu et al.

Nature Communications (2017)

Review Immunology

Anti-inflammatory Mechanisms Triggered by Apoptotic Cells during Their Clearance

Zsuzsa Szondy et al.

FRONTIERS IN IMMUNOLOGY (2017)

Review Biochemistry & Molecular Biology

ATP-induced Ca2+-signalling mechanisms in the regulation of mesenchymal stem cell migration

Lin-Hua Jiang et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Article Biochemistry & Molecular Biology

Tumor-derived factors affecting immune cells

Vincenzo Russo et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2017)

Review Biochemistry & Molecular Biology

Cytokines in immunogenic cell death: Applications for cancer immunotherapy

Anne Showalter et al.

CYTOKINE (2017)

Review Biochemistry & Molecular Biology

The Process and Regulatory Components of Inflammation in Brain Oncogenesis

A. G. M. Mostofa et al.

BIOMOLECULES (2017)

Article Pharmacology & Pharmacy

Immunosuppressive activities of adenosine in cancer

Bertrand Allard et al.

CURRENT OPINION IN PHARMACOLOGY (2016)

Review Oncology

Historical review of the causes of cancer

Clarke Brian Blackadar

WORLD JOURNAL OF CLINICAL ONCOLOGY (2016)

Review Biochemistry & Molecular Biology

Introduction: connexins, pannexins and their channels as gatekeepers of organ physiology

Mathieu Vinken

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Biochemistry & Molecular Biology

The P2X7 receptor regulates cell survival, migration and invasion of pancreatic ductal adenocarcinoma cells

Andrea Giannuzzo et al.

MOLECULAR CANCER (2015)

Article Cell Biology

Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival

Paul W. Furlow et al.

NATURE CELL BIOLOGY (2015)

Article Multidisciplinary Sciences

IL-33 activates tumor stroma to promote intestinal polyposis

Rebecca L. Maywald et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Cell Biology

Immunological mechanisms of the antitumor effects of supplemental oxygenation

Stephen M. Hatfield et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Immunology

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

Abhishek D. Garg et al.

FRONTIERS IN IMMUNOLOGY (2015)

Review Cell Biology

Connexins: junctional and non-junctional modulators of proliferation

Trond Aasen

CELL AND TISSUE RESEARCH (2015)

Article Oncology

Immune Escape Mechanisms as a Guide for Cancer Immunotherapy

Gregory L. Beatty et al.

CLINICAL CANCER RESEARCH (2015)

Article Biochemistry & Molecular Biology

IL-33/ST2 pathway contributes to metastasis of human colorectal

Xuejian Liu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Molecular mechanisms of ATP secretion during immunogenic cell death

I. Martins et al.

CELL DEATH AND DIFFERENTIATION (2014)

Review Immunology

Interleukin 33: a switch-hitting cytokine

Daniel O. Villarreal et al.

CURRENT OPINION IN IMMUNOLOGY (2014)

Article Dermatology

P2Y2R activation by nucleotides promotes skin wound-healing process

Hana Jin et al.

EXPERIMENTAL DERMATOLOGY (2014)

Review Biochemistry & Molecular Biology

Regulation of pannexin channels by post-translational modifications

Silvia Penuela et al.

FEBS LETTERS (2014)

Article Biochemistry & Molecular Biology

Pannexin 1 and Pannexin 3 Channels Regulate Skeletal Muscle Myoblast Proliferation and Differentiation

Stephanie Langlois et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

The P2Y2 Nucleotide Receptor Mediates the Proliferation and Migration of Human Hepatocellular Carcinoma Cells Induced by ATP

Rui Xie et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

Oscar R. Colegio et al.

NATURE (2014)

Review Cell Biology

Molecular mechanisms of epithelial-mesenchymal transition

Samy Lamouille et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Article Multidisciplinary Sciences

P2X7 Mediates ATP-Driven Invasiveness in Prostate Cancer Cells

Ying Qiu et al.

PLOS ONE (2014)

Article Multidisciplinary Sciences

Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment

Pallavi Chaturvedi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Physiology

The role of pannexin hemichannels in inflammation and regeneration

Helen P. Makarenkova et al.

FRONTIERS IN PHYSIOLOGY (2014)

Review Physiology

The pannexins: past and present

Stephen R. Bond et al.

FRONTIERS IN PHYSIOLOGY (2014)

Review Immunology

Extracellular adenosine-mediated modulation of regulatory T cells

Akio Ohta et al.

FRONTIERS IN IMMUNOLOGY (2014)

Review Immunology

Immunogenic Cell Death in Cancer Therapy

Guido Kroemer et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Review Biochemistry & Molecular Biology

The biochemistry and function of pannexin channels

Silvia Penuela et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

Article Oncology

P2Y2 receptor promotes cell invasion and metastasis in prostate cancer cells

W-H Li et al.

BRITISH JOURNAL OF CANCER (2013)

Article Medicine, Research & Experimental

mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice

Stefan Thiem et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Review Immunology

Interleukin-1α

Peleg Rider et al.

SEMINARS IN IMMUNOLOGY (2013)

Review Cell Biology

Many faces of DAMPs in cancer therapy

O. Krysko et al.

CELL DEATH & DISEASE (2013)

Review Biology

Detecting adenosine triphosphate in the pericellular space

Simonetta Falzoni et al.

INTERFACE FOCUS (2013)

Review Pharmacology & Pharmacy

Connexin and pannexin hernichannels in brain glial cells: properties, pharmacology, and roles

Christian Giaume et al.

FRONTIERS IN PHARMACOLOGY (2013)

Review Physiology

Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery

Sean P. Colgan et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)

Review Biochemistry & Molecular Biology

Biological role of connexin intercellular channels and hemichannels

Rekha Kar et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)

Review Biochemistry & Molecular Biology

Connexin and pannexin as modulators of myocardial injury

Antonio Rodriguez-Sinovas et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

Article Oncology

Expression of P2X7 Receptor Increases In Vivo Tumor Growth

Elena Adinolfi et al.

CANCER RESEARCH (2012)

Review Oncology

Purines, Purinergic Receptors, and Cancer

Francesco Di Virgilio

CANCER RESEARCH (2012)

Article Endocrinology & Metabolism

TGFβ modulates cell-to-cell communication in early epithelial-to-mesenchymal transition

C. E. Hills et al.

DIABETOLOGIA (2012)

Article Biochemistry & Molecular Biology

TGF-β-induced miR-21 negatively regulates the antiproliferative activity but has no effect on EMT of TGF-β in HaCaT cells

Tao Wang et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2012)

Review Biophysics

Mitochondrial redox signaling and cancer invasiveness

Linda Enns et al.

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2012)

Review Biotechnology & Applied Microbiology

CD73-Generated Adenosine: Orchestrating the Tumor-Stroma Interplay to Promote Cancer Growth

Bertrand Allard et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Article Oncology

The role of STAT3 activation in modulating the immune microenvironment of GBM

Alfred P. See et al.

JOURNAL OF NEURO-ONCOLOGY (2012)

Review Immunology

Inflammasomes in carcinogenesis and anticancer immune responses

Laurence Zitvogel et al.

NATURE IMMUNOLOGY (2012)

Article Immunology

P2 receptors and immunity

Amel Rayah et al.

MICROBES AND INFECTION (2012)

Review Biochemistry & Molecular Biology

Adenosine receptors and cancer

Stefania Gessi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

Article Oncology

Photodynamic Therapy of Cancer: An Update

Patrizia Agostinis et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2011)

Article Cell Biology

Epithelial-to-mesenchymal transformation alters electrical conductivity of human epicardial cells

Noortje A. M. Bax et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2011)

Article Immunology

Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy

Yuting Ma et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

Article Multidisciplinary Sciences

Inflammasome activation and IL-1β target IL-1α for secretion as opposed to surface expression

Antonia Fettelschoss et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

Mickael Michaud et al.

SCIENCE (2011)

Article Critical Care Medicine

Extracellular ATP Is a Danger Signal Activating P2X7 Receptor in Lung Inflammation and Fibrosis

Nicolas Riteau et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

Article Oncology

Emerging Therapeutic Targets and Agents for Glioblastoma Migrating Cells

Chunhui Di et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2010)

Review Cell Biology

HIF-1: upstream and downstream of cancer metabolism

Gregg L. Semenza

CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)

Review Oncology

Adenosine receptors as drug targets

Bertil B. Fredholm

EXPERIMENTAL CELL RESEARCH (2010)

Article Immunology

CD73 represses pro-inflammatory responses in human endothelial cells

Jana K. G. Gruenewald et al.

JOURNAL OF INFLAMMATION-LONDON (2010)

Review Biochemistry & Molecular Biology

Basal Release of ATP: An Autocrine-Paracrine Mechanism for Cell Regulation

Ross Corriden et al.

SCIENCE SIGNALING (2010)

Article Biochemistry & Molecular Biology

T-cadherin activates Rac1 and Cdc42 and changes endothelial permeability

E. V. Semina et al.

BIOCHEMISTRY-MOSCOW (2009)

Review Biochemistry & Molecular Biology

Pannexins, distant relatives of the connexin family with specific cellular functions?

Catheleyne D'hondt et al.

BIOESSAYS (2009)

Article Cell Biology

Chemotherapy induces ATP release from tumor cells

Isabelle Martins et al.

CELL CYCLE (2009)

Article Biochemistry & Molecular Biology

The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

William R. Silverman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

Michael R. Elliott et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors

Francois Ghiringhelli et al.

NATURE MEDICINE (2009)

Review Immunology

Myeloid-derived suppressor cells as regulators of the immune system

Dmitry I. Gabrilovich et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Review Immunology

Immunogenic and tolerogenic cell death

Douglas R. Green et al.

NATURE REVIEWS IMMUNOLOGY (2009)

Article Peripheral Vascular Disease

Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells

Evgenia V. Gerasimovskaya et al.

ANGIOGENESIS (2008)

Review Biochemistry & Molecular Biology

Pannexins and gap junction protein diversity

V. I. Shestopalov et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Review Biochemistry & Molecular Biology

Molecular characteristics of immunogenic cancer cell death

A. Tesniere et al.

CELL DEATH AND DIFFERENTIATION (2008)

Article Biochemistry & Molecular Biology

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

Chun-Jen Chen et al.

NATURE MEDICINE (2007)

Article Biochemistry & Molecular Biology

Pannexin-1 couples to maitotoxin- and nigericin-induced interleukin-1β release through a dye uptake-independent pathway

Pablo Pelegrin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Calreticulin exposure dictates the immunogenicity of cancer cell death

Michel Obeid et al.

NATURE MEDICINE (2007)

Article Endocrinology & Metabolism

ATP release mediates fluid flow-induced proliferation of human bone marrow stromal cells

Ryan C. Riddle et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2007)

Review Physiology

Physiology and pathophysiology of purinergic neurotransmission

Geoffrey Burnstock

PHYSIOLOGICAL REVIEWS (2007)

Review Biochemistry & Molecular Biology

Cancer metastasis:: Building a framework

Gaorav P. Gupta et al.

Article Biochemistry & Molecular Biology

Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor

Pablo Pelegrin et al.

EMBO JOURNAL (2006)

Article Multidisciplinary Sciences

A2A adenosine receptor protects tumors from antitumor T cells

Akio Ohta et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Cell Biology

Functional implications of calcium permeability of the channel formed by pannexin 1

Fabien Vanden Abeele et al.

JOURNAL OF CELL BIOLOGY (2006)

Review Pharmacology & Pharmacy

Pathophysiology and therapeutic potential of purinergic signaling

G Burnstock

PHARMACOLOGICAL REVIEWS (2006)

Article Cell Biology

A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion

P Pellegatti et al.

MOLECULAR BIOLOGY OF THE CELL (2005)

Review Oncology

Hereditary cancer predisposition syndromes

JE Garber et al.

JOURNAL OF CLINICAL ONCOLOGY (2005)

Article Biochemistry & Molecular Biology

P2Y receptors play a critical role in epithelial cell communication and migration

VE Klepeis et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2004)

Article Multidisciplinary Sciences

Pannexins, a family of gap junction proteins expressed in brain

R Bruzzone et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Physiology

Plasma membrane channels formed by connexins:: Their regulation and functions

JC Sáez et al.

PHYSIOLOGICAL REVIEWS (2003)

Review Biochemistry & Molecular Biology

Extracellular ATP as a signaling molecule for epithelial cells

EM Schwiebert et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)

Review Immunology

A blast from the past: Clearance of apoptotic cells regulates immune responses

J Savill et al.

NATURE REVIEWS IMMUNOLOGY (2002)

Review Immunology

Cancer immunoediting: from immunosurveillance to tumor escape

GP Dunn et al.

NATURE IMMUNOLOGY (2002)

Review Physiology

Molecular physiology of P2X receptors

RA North

PHYSIOLOGICAL REVIEWS (2002)

Article Biochemistry & Molecular Biology

Mechanically induced ATP release from human osteoblastic cells

M Romanello et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)

Review Biochemistry & Molecular Biology

Purinergic signalling: ATP release

P Bodin et al.

NEUROCHEMICAL RESEARCH (2001)

Article Immunology

Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells

DI Gabrilovich et al.

JOURNAL OF IMMUNOLOGY (2001)

Article Cell Biology

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

G Bergers et al.

NATURE CELL BIOLOGY (2000)

Article Cell Biology

p120 catenin regulates the actin cytoskeleton via Rho family GTPases

NK Noren et al.

JOURNAL OF CELL BIOLOGY (2000)

Article Pharmacology & Pharmacy

P2Y2 receptor-mediated proliferation of C6 glioma cells via activation of Ras/Raf/MEK/MAPK pathway

MT Tu et al.

BRITISH JOURNAL OF PHARMACOLOGY (2000)

Article Medicine, Research & Experimental

A role for heterologous gap junctions between melanoma and endothelial cells in metastasis

A Ito et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)