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Insulin-like Growth Factor-Binding Protein-7 Functions as a Potential Tumor Suppressor in Hepatocellular Carcinoma
Dong Chen et al.
CLINICAL CANCER RESEARCH (2011)
Regulation of Cancer Stem Cells by Cytokine Networks: Attacking Cancer's Inflammatory Roots
Hasan Korkaya et al.
CLINICAL CANCER RESEARCH (2011)
Hippo signaling: growth control and beyond
Georg Halder et al.
DEVELOPMENT (2011)
A phase I study of AVE1642, a human monoclonal antibody-blocking insulin-like growth factor-1 receptor (IGF-1R), given as a single agent and in combination with sorafenib as first-line therapy in patients with advanced hepatocellular carcinoma (HCC).
S. J. Faivre et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Phase II study of cixutumumab (IMC-A12, NSC742460; C) in hepatocellular carcinoma (HCC)
G. K. Abou-Alfa et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Targeting insulin-like growth factor axis in hepatocellular carcinoma
Jennifer Wu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2011)
Yki/YAP, Sd/TEAD and Hth/MEIS Control Tissue Specification in the Drosophila Eye Disc Epithelium
Tianyi Zhang et al.
PLOS ONE (2011)
Viral hepatitis and HIV co-infection
Vincent Soriano et al.
ANTIVIRAL RESEARCH (2010)
Normal values of serum IGF-1 in adults: results from a Brazilian population
Pedro Weslley Rosario
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA (2010)
Transcriptional down-regulation of IGFBP-3 in human hepatocellular carcinoma cells is mediated by the binding of TIA-1 to its AT-rich element in the 3′-untranslated region
Kothandharaman Subramaniam et al.
CANCER LETTERS (2010)
Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells
Tamara Aleksic et al.
CANCER RESEARCH (2010)
MicroRNA: Biogenesis, Function and Role in Cancer
Leigh-Ann MacFarlane et al.
CURRENT GENOMICS (2010)
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
The Hepatitis B Virus X Protein Modulates Hepatocyte Proliferation Pathways To Stimulate Viral Replication
Tricia L. Gearhart et al.
JOURNAL OF VIROLOGY (2010)
Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer
A. J. Ryan et al.
BRITISH JOURNAL OF CANCER (2009)
Sorafenib A Review of its Use in Advanced Hepatocellular Carcinoma
Gillian M. Keating et al.
DRUGS (2009)
Cixutumumab
Kevin P. McKian et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2009)
Discovery of OSI-906: a selective and orally efficacious dual inhibitor of the IGF-I receptor and insulin receptor
Mark J. Mulvihill et al.
FUTURE MEDICINAL CHEMISTRY (2009)
TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation
Siew Wee Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
Ann-Lii Cheng et al.
LANCET ONCOLOGY (2009)
Daintain/AIF-1 promotes breast cancer proliferation via activation of the NF-κB/cyclin D1 pathway and facilitates tumor growth
Shou Liu et al.
CANCER SCIENCE (2008)
The Expression of Hypoxia-Inducible Factor-1 alpha in Hepatitis B Virus-Related Hepatocellular Carcinoma: Correlation with Patients' Prognosis and Hepatitis B Virus X Protein
Huahong Xie et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
TEAD mediates YAP-dependent gene induction and growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2008)
Molecular targeted therapies in hepatocellular carcinoma
Josep M. Llovet et al.
HEPATOLOGY (2008)
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins
Marta Guix et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Oxidative stress in alcoholic liver disease: Role of NADPH oxidase complex
Samele De Minicis et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Effects of parenteral nutrition without and with growth hormone on growth hormone/insulin-like growth factor-1 axis after hepatectomy in hepatocellular carcinoma with liver cirrhosis
Jie Cao et al.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2007)
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
Sean C. Bendall et al.
NATURE (2007)
Evaluation and management of obesity-related nonalcoholic fatty liver disease
Clare Nugent et al.
NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2007)
IGF1R signalling and its inhibition
J. Riedemann et al.
ENDOCRINE-RELATED CANCER (2006)
Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib
Christele Desbois-Mouthon et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Downregulation of miR-122 in the rodent and human hepatocellular carcinomas
Huban Kutay et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
Cytokines and alcohol
FT Crews et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2006)
A microRNA expression signature of human solid tumors defines cancer gene targets
S Volinia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Effects of hepatitis B virus X protein on the development of liver cancer
XD Zhang et al.
JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2006)
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome
M Murakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members
WM Mahoney et al.
BIOCHEMICAL JOURNAL (2005)
IGF-I induces DNA synthesis and apoptosis in rat liver hepatic stellate cells (HSC) but DNA synthesis and proliferation in rat liver myofibroblasts (rMF)
B Saile et al.
LABORATORY INVESTIGATION (2004)
Synergistic interaction between aflatoxin B1 and hepatitis B virus in hepatocarcinogenesis
MC Kew
LIVER INTERNATIONAL (2003)
Insulin-like growth factor binding protein proteolysis
RC Bunn et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2003)
Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis
Z Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2003)
Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ
CB Cui et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
CL Thio et al.
LANCET (2002)
Hepatitis C and HIV co-infection: a review
I Maier et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2002)
Targeted expression of a protease-resistant IGFBP-4 mutant in smooth muscle of transgenic mice results in IGFBP-4 stabilization and smooth muscle hypotrophy
MY Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Insulin-like growth factors and cancer
G Fürstenberger et al.
LANCET ONCOLOGY (2002)
Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway
M Forgues et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The IGF axis and hepatocarcinogenesis
JG Scharf et al.
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY (2001)
TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
A Vassilev et al.
GENES & DEVELOPMENT (2001)
Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells
AJ Butt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)