Journal
HYPERTENSION RESEARCH
Volume 44, Issue 7, Pages 858-865Publisher
SPRINGERNATURE
DOI: 10.1038/s41440-021-00628-y
Keywords
Population attributable fraction; Home hypertension; Risk factor; Public health; Japanese
Categories
Funding
- Reconstruction Agency
- Ministry of Education, Culture, Sports, Science and Technology (MEXT)
- Japan Agency for Medical Research and Development (AMED) [JP15km0105001, JP16km0105001, JP17km0105001]
- Omron Healthcare Co., Ltd.
Ask authors/readers for more resources
Recent studies have identified a high urinary sodium-to-potassium ratio and reduced sleep efficiency, in addition to traditional risk factors like obesity and excessive alcohol intake, as risk factors for hypertension. The impact of these overall risk factors on hypertension, including the urinary Na/K ratio and sleep efficiency, appears to be higher than that of conventional risk factors alone. Managing these factors, along with traditional risk factors, may be important in hypertension management.
Recently, a high urinary sodium-to-potassium (Na/K) ratio and reduced sleep efficiency, in addition to conventional risk factors (obesity and excess alcohol intake), have been identified as risk factors for hypertension. We estimated the population attributable fraction (PAF) for home hypertension due to these risk factors in a general Japanese population. We conducted a cross-sectional study including 1384 participants (393 men and 991 women) to estimate the odds ratio (OR) and 95% confidence interval (CI) for the presence of any of the conventional risk factors using multivariable logistic regression analyses. The models were adjusted for sex, age, smoking status, and log-transformed average daily steps. We also estimated the OR and 95% CI for the presence of any of the overall risk factors. Furthermore, we calculated the PAF due to these risk factors. The results showed that the prevalence of home hypertension was 39.0% (540/1384). The presence of any of the conventional risk factors, as well as any of the overall risk factors, was significantly associated with an increased prevalence of hypertension (OR 2.80, 95% CI 2.15-3.65; OR 2.50, 95% CI 1.93-3.22, respectively). The PAF for hypertension due to the presence of any of the conventional risk factors and the PAF due to the presence of any of the overall risk factors were 30.2% and 39.0%, respectively. In conclusion, the impact of the overall risk factors, including the urinary Na/K ratio and sleep efficiency, on home hypertension was higher than that of conventional risk factors alone. The management of the urinary Na/K ratio and sleep efficiency as well as conventional risk factors might be important in the management of blood pressure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available