4.7 Review

An Academic Clinician's Road Map to Hypertension Genomics Recent Advances and Future Directions MMXX

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Body mass index and body composition in relation to 14 cardiovascular conditions in UK Biobank: a Mendelian randomization study

Susanna C. Larsson et al.

EUROPEAN HEART JOURNAL (2020)

Article Medicine, General & Internal

Predictive Accuracy of a Polygenic Risk Score-Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

Joshua Elliott et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Editorial Material Medicine, General & Internal

Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease?

Sadiya S. Khan et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Medicine, General & Internal

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

Jonathan D. Mosley et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Peripheral Vascular Disease

The impact of glycated hemoglobin on risk of hypertension: a Mendelian randomization study using UK Biobank

Shiu Lun Au Yeung et al.

JOURNAL OF HYPERTENSION (2020)

Article Cardiac & Cardiovascular Systems

Identification of Circulating Proteins Associated With Blood Pressure Using Mendelian Randomization

Sebastien Theriault et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2020)

Article Mathematical & Computational Biology

Estimation of clinical trial success rates and related parameters

Chi Heem Wong et al.

BIOSTATISTICS (2019)

Article Peripheral Vascular Disease

Evidence for a Causal Role of the SH2B3-2M Axis in Blood Pressure Regulation: Framingham Heart Study

Joshua A. Keefe et al.

HYPERTENSION (2019)

Review Genetics & Heredity

Benefits and limitations of genome-wide association studies

Vivian Tam et al.

NATURE REVIEWS GENETICS (2019)

Article Medicine, General & Internal

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study

Alice R. Carter et al.

BMJ-BRITISH MEDICAL JOURNAL (2019)

Review Genetics & Heredity

On the utilization of polygenic risk scores for therapeutic targeting

Greg Gibson

PLOS GENETICS (2019)

Article Cardiac & Cardiovascular Systems

Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects

Dipender Gill et al.

CIRCULATION (2019)

Article Cardiac & Cardiovascular Systems

Genetically modulated educational attainment and coronary disease risk

Lingyao Zeng et al.

EUROPEAN HEART JOURNAL (2019)

Editorial Material Public, Environmental & Occupational Health

Mendelian randomization: the challenge of unobserved environmental confounds

Philipp D. Koellinger et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2019)

Article Public, Environmental & Occupational Health

Relationship between alcohol use, blood pressure and hypertension: an association study and a Mendelian randomisation study

Pian-Pian Zhao et al.

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2019)

Review Biochemistry & Molecular Biology

Validity of polygenic risk scores: are we measuring what we think we are?

A. Cecile J. W. Janssens

HUMAN MOLECULAR GENETICS (2019)

Article Medicine, General & Internal

Effects of Serelaxin in Patients with Acute Heart Failure

Marco Metra et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Multidisciplinary Sciences

Projecting burden of hypertension and its management in Turkey, 2015-2030

Ayda Aysun Yurekli et al.

PLOS ONE (2019)

Article Genetics & Heredity

Assembly of a pan-genome from deep sequencing of 910 humans of African descent

Rachel M. Sherman et al.

NATURE GENETICS (2019)

Article Cardiac & Cardiovascular Systems

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes A Wide-Angled Mendelian Randomization Investigation

Elias Allara et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2019)

Review Cardiac & Cardiovascular Systems

PCSK9 From Basic Science Discoveries to Clinical Trials

Michael D. Shapiro et al.

CIRCULATION RESEARCH (2018)

Review Genetics & Heredity

Genotype Imputation from Large Reference Panels

Sayantan Das et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 19 (2018)

Article Cardiac & Cardiovascular Systems

Trends in Healthcare Expenditures Among US Adults With Hypertension: National Estimates, 2003-2014

Elizabeth B. Kirkland et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

Review Peripheral Vascular Disease

Epigenetic Mechanisms and Hypertension

Mingyu Liang

HYPERTENSION (2018)

Review Peripheral Vascular Disease

Noncoding RNAs in the Regulatory Network of Hypertension

Gengze Wu et al.

HYPERTENSION (2018)

Review Oncology

Hypertension genomics and cardiovascular prevention

Fu Liang Ng et al.

ANNALS OF TRANSLATIONAL MEDICINE (2018)

Article Cardiac & Cardiovascular Systems

Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease Addressing the Barker Hypothesis With Mendelian Randomization

Daniela Zanetti et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2018)

Article Biochemistry & Molecular Biology

The ChEMBL database in 2017

Anna Gaulton et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Medicine, General & Internal

Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015

Mohammad H. Forouzanfar et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Review Urology & Nephrology

Novel Paradigms of Salt and Hypertension

Wenguang Feng et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Article Genetics & Heredity

Reevaluation of SNP heritability in complex human traits

Doug Speed et al.

NATURE GENETICS (2017)

Article Biochemistry & Molecular Biology

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

Kelsy C Cotto et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Biochemistry & Molecular Biology

Cardiovascular effects of exogenous adrenomedullin and CGRP in Ramp and Calcrl deficient mice

J. B. Pawlak et al.

PEPTIDES (2017)

Article Medicine, General & Internal

Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

Ming Ding et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Medicine, General & Internal

Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

Ming Ding et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Multidisciplinary Sciences

Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

Catarina Rippe et al.

SCIENTIFIC REPORTS (2017)

Review Biochemistry & Molecular Biology

An Expanded View of Complex Traits: From Polygenic to Omnigenic

Evan A. Boyle et al.

Article Public, Environmental & Occupational Health

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

Eveline Nuesch et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2016)

Article Health Care Sciences & Services

Million Veteran Program: A mega-biobank to study genetic influences on health and disease

John Michael Gaziano et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Effect of Smoking on Blood Pressure and Resting Heart Rate A Mendelian Randomization Meta-Analysis in the CARTA Consortium

Allan Linneberg et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2015)

Article Genetics & Heredity

The support of human genetic evidence for approved drug indications

Matthew R. Nelson et al.

NATURE GENETICS (2015)

Review Medicine, Research & Experimental

Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics

Claudia P. Cabrera et al.

WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2015)

Article Genetics & Heredity

A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension

Tianxiao Huan et al.

PLOS GENETICS (2015)

Article Cardiac & Cardiovascular Systems

Effect of Smoking on Blood Pressure and Resting Heart Rate A Mendelian Randomization Meta-Analysis in the CARTA Consortium

Allan Linneberg et al.

CIRCULATION-CARDIOVASCULAR GENETICS (2015)

Article Biochemistry & Molecular Biology

Life insurance: genomic stratification and risk classification

Yann Joly et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2014)

Article Peripheral Vascular Disease

Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis

William L. Baker et al.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2014)

Article Biotechnology & Applied Microbiology

Clinical development success rates for investigational drugs

Michael Hay et al.

NATURE BIOTECHNOLOGY (2014)

Article Endocrinology & Metabolism

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

Karani S. Vimaleswaran et al.

LANCET DIABETES & ENDOCRINOLOGY (2014)

Review Cardiac & Cardiovascular Systems

Genes for blood pressure: an opportunity to understand hypertension

Georg B. Ehret et al.

EUROPEAN HEART JOURNAL (2013)

Article Biochemistry & Molecular Biology

Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension

Idris Guessous et al.

HUMAN MOLECULAR GENETICS (2012)

Review Biotechnology & Applied Microbiology

Interpreting noncoding genetic variation in complex traits and human disease

Lucas D. Ward et al.

NATURE BIOTECHNOLOGY (2012)

Article Genetics & Heredity

Heritability and Genetic Correlations Explained by Common SNPs for Metabolic Syndrome Traits

Shashaank Vattikuti et al.

PLOS GENETICS (2012)

Article Public, Environmental & Occupational Health

Use of A Mendelian Randomization Approach to Assess the Causal Relation of γ-Glutamyltransferase with Blood Pressure and Serum Insulin Levels

David Conen et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2010)

Article Medicine, General & Internal

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure - The JNC 7 Report

AV Chobanian et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)