Journal
HUMAN BRAIN MAPPING
Volume 42, Issue 7, Pages 2214-2235Publisher
WILEY
DOI: 10.1002/hbm.25361
Keywords
attention-deficit/hyperactivity disorder; borderline personality disorder; gray matter; impulsivity; magnetic resonance imaging; meta-analysis; psychoradiology; voxel-based morphometry
Funding
- China Postdoctoral Science Foundation [2019M653421]
- National Natural Science Foundation of China [31800963, 81621003, 81820108018, 82027808]
Ask authors/readers for more resources
The study provides an integrated delineation of gray matter substrates related to trait impulsivity, highlighting volumetric GM alterations in prefrontal, temporal, and parietal cortices. Furthermore, the modulatory effects of age and gender in impulsivity-GM volume associations were identified, advancing understanding of brain GM morphometry features underlying trait impulsivity with potential implications for clinical diagnosis and intervention.
Trait impulsivity is a multifaceted personality characteristic that contributes to maladaptive life outcomes. Although a growing body of neuroimaging studies have investigated the structural correlates of trait impulsivity, the findings remain highly inconsistent and heterogeneous. Herein, we performed a systematic review to depict an integrated delineation of gray matter (GM) substrates of trait impulsivity and a meta-analysis to examine concurrence across previous whole-brain voxel-based morphometry studies. The systematic review summarized the diverse findings in GM morphometry in the past literature, and the quantitative meta-analysis revealed impulsivity-related volumetric GM alterations in prefrontal, temporal, and parietal cortices. In addition, we identified the modulatory effects of age and gender in impulsivity-GM volume associations. The present study advances understanding of brain GM morphometry features underlying trait impulsivity. The findings may have practical implications in the clinical diagnosis of and intervention for impulsivity-related disorders.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available