Related references
Note: Only part of the references are listed.Fluorescent ligands: Bringing light to emerging GPCR paradigms
Mark Soave et al.
BRITISH JOURNAL OF PHARMACOLOGY (2020)
Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor
Eleonora Comeo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
Julia Ast et al.
NATURE COMMUNICATIONS (2020)
Improved GPCR ligands from nanobody tethering
Ross W. Cheloha et al.
NATURE COMMUNICATIONS (2020)
Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses
Brianna N. Callahan et al.
FRONTIERS IN IMMUNOLOGY (2020)
Opioid Pharmacology under the Microscope
Damien Jullie et al.
MOLECULAR PHARMACOLOGY (2020)
A Quantitative Proteome Map of the Human Body
Lihua Jiang et al.
CELL (2020)
Humanized GPRC6AKGKY is a gain-of-function polymorphism in mice
Min Pi et al.
SCIENTIFIC REPORTS (2020)
Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells
Leigh A. Stoddart et al.
COMMUNICATIONS BIOLOGY (2020)
Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies
Mark Soave et al.
CELL CHEMICAL BIOLOGY (2020)
Data describing expression of formyl peptide receptor 2 in human articular chondrocytes
Alexander Strid Holmertz et al.
DATA IN BRIEF (2020)
CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes
Carl W. White et al.
CELL CHEMICAL BIOLOGY (2020)
A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice
Lucie Esteoulle et al.
CHEMICAL SCIENCE (2020)
NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing
Carl W. White et al.
CELLULAR SIGNALLING (2019)
Nanobodies: New avenues for imaging, stabilizing and modulating GPCRs
Timo W. M. De Groof et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)
Nanobodies detecting and modulating GPCRs outside in and inside out
Raimond Heukers et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
Binding kinetics of ligands acting at GPCRs
David A. Sykes et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)
Nanobody-Targeted Photodynamic Therapy Selectively Kills Viral GPCR-Expressing Glioblastoma Cells
Timo W. M. De Groof et al.
MOLECULAR PHARMACEUTICS (2019)
Antibodies Targeting Chemokine Receptors CXCR4 and ACKR3
Vladimir Bobkov et al.
MOLECULAR PHARMACOLOGY (2019)
A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors
Guangsen Shi et al.
NEURON (2019)
Detection and Quantification of GPCR mRNA: An Assessment and Implications of Data from High-Content Methods
Krishna Sriram et al.
ACS OMEGA (2019)
Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in
Abdullah O. Khan et al.
SCIENTIFIC REPORTS (2019)
Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry
Seksiri Arttamangkul et al.
ELIFE (2019)
Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems
Tomonori Tamura et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
GPR18 expression on PMNs as biomarker for outcome in patient with sepsis
Lanqiu Zhang et al.
LIFE SCIENCES (2019)
Complex Formation between VEGFR2 and the β2-Adrenoceptor
Laura E. Kilpatrick et al.
CELL CHEMICAL BIOLOGY (2019)
A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines
Mark Soave et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Pharmacogenomics of GPCR Drug Targets
Alexander S. Hauser et al.
CELL (2018)
Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells
Marjolein Soethoudt et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Krishna Sriram et al.
MOLECULAR PHARMACOLOGY (2018)
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
Conor McMahon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth
Raimond Heukers et al.
ONCOGENE (2018)
Genome Editing Provides New Insights into Receptor-Controlled Signalling Pathways
Graeme Milligan et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Studying GPCR Pharmacology in Membrane Microdomains: Fluorescence Correlation Spectroscopy Comes of Age
Stephen J. Briddon et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
Conor McMahon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Anti-fibrotic Effects of CXCR4-Targeting i-body AD-114 in Preclinical Models of Pulmonary Fibrosis
K. Griffiths et al.
SCIENTIFIC REPORTS (2018)
Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells
Leigh A. Stoddart et al.
SCIENTIFIC REPORTS (2018)
Identification and functional characterization of arginine vasopressin receptor 1A: atypical chemokine receptor 3 heteromers in vascular smooth muscle
Lauren J. Albee et al.
OPEN BIOLOGY (2018)
Synthetic single domain antibodies for the conformational trapping of membrane proteins
Iwan Zimmermann et al.
ELIFE (2018)
An Affinity-Based Probe for the Human Adenosine A2A Receptor
Xue Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
CXCR4-targeting nanobodies differentially inhibit CXCR4 function and HIV entry
Anneleen Van Hout et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Nanobody-Fc constructs targeting chemokine receptor CXCR4 potently inhibit signaling and CXCR4-mediated HIV-entry and induce antibody effector functions
Vladimir Bobkov et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Development and characterisation of a novel glucagon like peptide-1 receptor antibody
Emma K. Biggs et al.
DIABETOLOGIA (2018)
Proof of Therapeutic Efficacy of a 177Lu-Labeled Neurotensin Receptor 1 Antagonist in a Colon Carcinoma Xenograft Model
Joerg Schulz et al.
JOURNAL OF NUCLEAR MEDICINE (2017)
CXCR4-Specific Nanobodies as Potential Therapeutics for WHIM syndrome
Raymond H. de Wit et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors
Catherine J. Hutchings et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors
Anneleen van Hout et al.
PLOS ONE (2017)
Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription
Amod Godbole et al.
NATURE COMMUNICATIONS (2017)
Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time
Carl W. White et al.
SCIENTIFIC REPORTS (2017)
How Ligands Illuminate GPCR Molecular Pharmacology
Daniel Wacker et al.
CELL (2017)
NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells
Andrew S. Dixon et al.
ACS CHEMICAL BIOLOGY (2016)
Discovery of functional monoclonal antibodies targeting G-protein-coupled receptors and ion channels
Trevor C. I. Wilkinson
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Immunosuppressive activities of adenosine in cancer
Bertrand Allard et al.
CURRENT OPINION IN PHARMACOLOGY (2016)
i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4
Katherine Griffiths et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Discovery of the First Environment-Sensitive Near-Infrared (NIR) Fluorogenic Ligand for α1-Adrenergic Receptors Imaging in Vivo
Zhao Ma et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Targeted Imaging of the Atypical Chemokine Receptor 3 (ACKR3/CXCR7) in Human Cancer Xenografts
Babak Behnam Azad et al.
JOURNAL OF NUCLEAR MEDICINE (2016)
In Vitro and In Vivo Characterization of Selected Fluorine-18 Labeled Radioligands for PET Imaging of the Dopamine D3 Receptor
Natascha Nebel et al.
MOLECULES (2016)
A scalable strategy for high-throughput GFP tagging of endogenous human proteins
Manuel D. Leonetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A fully human CXCR4 antibody demonstrates diagnostic utility and therapeutic efficacy in solid tumor xenografts
Babak Behnam Azad et al.
ONCOTARGET (2016)
Pharmacologic Characterization of AMG 334, a Potent and Selective Human Monoclonal Antibody against the Calcitonin Gene-Related Peptide Receptor
Licheng Shi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Regulation of Oligomeric Organization of the Serotonin 5-Hydroxytryptamine 2C (5-HT2C) Receptor Observed by Spatial Intensity Distribution Analysis
Richard J. Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management
Folabomi A. Oladosu et al.
MAYO CLINIC PROCEEDINGS (2015)
Application of BRET to monitor ligand binding to GPCRs
Leigh A. Stoddart et al.
NATURE METHODS (2015)
BODIPY® FL Histamine as a New Modality for Quantitative Detection of Histamine Receptor Upregulation Upon IgE Sensitization in Murine Bone Marrow-Derived Mast Cells
Arash Mirzahosseini et al.
CYTOMETRY PART A (2015)
G Protein-Coupled Receptor (GPCR) Expression in Native Cells: Novel endoGPCRs as Physiologic Regulators and Therapeutic Targets
Paul A. Insel et al.
MOLECULAR PHARMACOLOGY (2015)
Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action
M. E. Bradley et al.
MOLECULAR PHARMACOLOGY (2015)
Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors
Rajashri Sridharan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
The evolving small-molecule fluorescent-conjugate toolbox for Class A GPCRs
Andrea J. Vernall et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
LDAI-Based Chemical Labeling of Intact Membrane Proteins and Its Pulse-Chase Analysis under Live Cell Conditions
Takayuki Miki et al.
CHEMISTRY & BIOLOGY (2014)
Cell Surface Profiling Using High-Throughput Flow Cytometry: A Platform for Biomarker Discovery and Analysis of Cellular Heterogeneity
Craig A. Gedye et al.
PLOS ONE (2014)
Structure-Based Design of Reactive Nucleosides for Site-Specific Modification of the A2A Adenosine Receptor
Steven M. Moss et al.
ACS MEDICINAL CHEMISTRY LETTERS (2014)
Nanobodies: Natural Single-Domain Antibodies
Serge Muyldermans
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)
Characterization by flow cytometry of fluorescent, selective agonist probes of the A3 adenosine receptor
Eszter Kozma et al.
BIOCHEMICAL PHARMACOLOGY (2013)
BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies
Michelle R. Kuhne et al.
CLINICAL CANCER RESEARCH (2013)
Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes
Ross Corriden et al.
EMBO REPORTS (2013)
Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor
Peter Ravn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Llama-derived Single Variable Domains (Nanobodies) Directed against Chemokine Receptor CXCR7 Reduce Head and Neck Cancer Cell Growth in Vivo
David Maussang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Radiolabeling and in vitro/in vivo evaluation of N-(1-adamantyl)-8-methoxy-4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxamide as a PET probe for imaging cannabinoid type 2 receptor
Linjing Mu et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Conformational biosensors reveal GPCR signalling from endosomes
Roshanak Irannejad et al.
NATURE (2013)
Site-specific N-terminal labeling of proteins using sortase-mediated reactions
Christopher S. Theile et al.
NATURE PROTOCOLS (2013)
Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization
Davide Calebiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs
Andrea Strasser et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands
Rachel H. Rose et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Specificity evaluation of antibodies against human β3-adrenoceptors
Hana Cernecka et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2012)
Design and evaluation of a novel fluorescent CB2 ligand as probe for receptor visualization in immune cells
Ravil R. Petrov et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Soren G. F. Rasmussen et al.
NATURE (2011)
Defucosylated Humanized Anti-CCR4 Monoclonal Antibody KW-0761 as a Novel Immunotherapeutic Agent for Adult T-cell Leukemia/Lymphoma
Toshihiko Ishii et al.
CLINICAL CANCER RESEARCH (2010)
Therapeutic antibodies directed at G protein-coupled receptors
Catherine J. Hutchings et al.
MABS (2010)
A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells
Carina Banning et al.
PLOS ONE (2010)
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
Sven Jahnichen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Alternative splicing of G protein-coupled receptors: physiology and pathophysiology
Danijela Markovic et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys
Hai Yan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
How reliable are G-protein-coupled receptor antibodies?
Martin C. Michel et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2009)
Lack of specificity of commercially available antisera against muscarinergic and adrenergic receptors
Wisuit Pradidarcheep et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2009)
Persistent cAMP-Signals Triggered by Internalized G-Protein-Coupled Receptors
Davide Calebiro et al.
PLOS BIOLOGY (2009)
Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain
J. Guindon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Anatomical Profiling of G Protein-Coupled Receptor Expression
Jean B. Regard et al.
CELL (2008)
Specific detection of CB1 receptors;: cannabinoid CB1 receptor antibodies are not all created equal!
Natasha L. Grimsey et al.
JOURNAL OF NEUROSCIENCE METHODS (2008)
Highly inclined thin illumination enables clear single-molecule imaging in cells
Makio Tokunaga et al.
NATURE METHODS (2008)
Tools to study β3-adrenoceptors
Wim Vrydag et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2007)
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies
E De Genst et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Fluorophore-tagged GPCR ligands
RJ Middleton et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2005)
Quantitative in vitro phosphor imaging using [3H] and [18F] radioligands:: the effects of chronic desipramine treatment on serotonin 5-HT2 receptors
EM Strome et al.
JOURNAL OF NEUROSCIENCE METHODS (2005)
Fluorescent CXCL12AF647 as a novel probe for nonradioactive CXCL12/CXCR4 cellular interaction studies
S Hatse et al.
CYTOMETRY PART A (2004)
Flow cytometry for high-throughput, high-content screening
BS Edwards et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2004)
Fluorescent ligands, antibodies, and proteins for the study of receptors
CJ Daly et al.
PHARMACOLOGY & THERAPEUTICS (2003)
The G protein-coupled receptor repertoires of human and mouse
DK Vassilatis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Dopamine receptor expression on human T- and B-lymphocytes, monocytes, neutrophils, eosinophils and NK cells: a flow cytometric study
F McKenna et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use
JC Reubi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE (2000)