Journal
EUROPEAN JOURNAL OF ENDOCRINOLOGY
Volume 184, Issue 2, Pages E5-E9Publisher
BIOSCIENTIFICA LTD
DOI: 10.1530/EJE-20-1239
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Funding
- National Institute for Health Research (NIHR) Clinician Scientist Fellowship [NIHR-CS-2015-15-016]
- NIHR Postdoctoral Fellowship
- NIHR Statistics Group
- NIHR Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust
- University of Birmingham
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Diagnostic accuracy studies are crucial for evaluating diagnostic tests. Researchers should choose appropriate study designs, analyze results using correct methods, and avoid exaggerating conclusions, while also considering the clinical context for balancing sensitivity and specificity. Transparent reporting using the STARD checklist is recommended for test accuracy studies.
Diagnostic accuracy studies are fundamental for the assessment of diagnostic tests. Researchers need to understand the implications of their chosen design, opting for comparative designs where possible. Researchers should analyse test accuracy studies using the appropriate methods, acknowledging the uncertainty of results and avoiding overstating conclusions and ignoring the clinical situation which should inform the trade-off between sensitivity and specificity. Test accuracy studies should be reported with transparency using the STAndards for the Reporting of Diagnostic accuracy studies (STARD) checklist.
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