4.6 Article

SARS-CoV-2 re-infection risk in Austria

Related references

Note: Only part of the references are listed.
Article Immunology

A longitudinal study of SARS-CoV-2-infected patients reveals a high correlation between neutralizing antibodies and COVID-19 severity

Vincent Legros et al.

Summary: The study investigated the neutralizing antibody response in serum samples from 140 confirmed SARS-CoV-2 infections, finding that antibody titers correlated with disease severity and anti-spike IgG levels. Post-recovery, patients' nAb activity declined more rapidly compared to individuals infected with other coronaviruses, and previous infection by human coronaviruses did not generate protective nAbs against SARS-CoV-2. Additionally, the D614G mutation in the spike protein did not lead to neutralization escape.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

Article Immunology

The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers

Sheila F. Lumley et al.

Summary: In this study, it was found that anti-nucleocapsid antibodies against SARS-CoV-2 decline within a few months, with higher titers associated with longer duration. On the other hand, anti-spike IgG remained stably detected. Factors such as age, ethnicity, and symptom presentation also had an impact on antibody levels.

CLINICAL INFECTIOUS DISEASES (2021)

Review Immunology

Reinfection With SARS-CoV-2: Implications for Vaccines

Jeffrey Cohen et al.

Summary: The likelihood and duration of reinfection with SARS-CoV-2 remain uncertain, as current knowledge on this topic is limited. Studies on other respiratory viruses suggest that serum antibodies typically persist for only a few months to a few years, making reinfections common. These findings have implications for vaccine development and the need for continued protective measures.

CLINICAL INFECTIOUS DISEASES (2021)

Letter Infectious Diseases

Prior SARS-CoV-2 infection is associated with protection against symptomatic reinfection

Aidan T. Hanrath et al.

JOURNAL OF INFECTION (2021)

Article Medicine, General & Internal

Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

S. F. Lumley et al.

Summary: In a longitudinal study of seropositive and seronegative health care workers undergoing asymptomatic and symptomatic SARS-CoV-2 testing, the presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a substantially reduced risk of SARS-CoV-2 reinfection in the ensuing 6 months.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Immunology

Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission

Young-Il Kim et al.

Summary: The study found that ferrets with high NAb titres after SARS-CoV-2 infection showed attenuated viral replication and rapid viral clearance upon reinfection, while ferrets with low NAb titres were more prone to reinfection.

EMERGING MICROBES & INFECTIONS (2021)

Article Public, Environmental & Occupational Health

SARS-CoV-2 antibody seroprevalence in India, August-September, 2020: findings from the second nationwide household serosurvey

Manoj Murhekar et al.

Summary: The seroprevalence of SARS-CoV-2 infection in individuals aged 10 years or older in India was 6.6%, with a higher prevalence of 7.1% in adults, and the highest prevalence seen in urban slum areas.

LANCET GLOBAL HEALTH (2021)

Review Infectious Diseases

Recurrence of SARS-CoV-2 viral RNA in recovered COVID-19 patients: a narrative review

Thi Loi Dao et al.

Summary: Many studies have shown re-positive tests for SARS-CoV-2 in recovered COVID-19 patients are common, with proportions varying depending on population size, age, and sample types. False-negative tests, reactivation, and re-infection are suggested as potential causes, emphasizing the need for novel assays targeting crucial regions of the RNA genome to improve sensitivity and specificity.

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES (2021)

Article Public, Environmental & Occupational Health

Infection fatality rate of COVID-19 inferred from seroprevalence data

John P. A. Ioannidis

Summary: This study aimed to estimate the infection fatality rate of COVID-19 using seroprevalence data. The findings showed that the infection fatality rate varied significantly across different locations due to differences in population age structure, case mix of infected and deceased patients, and other factors. The inferred infection fatality rates were generally lower than earlier estimates made during the pandemic.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2021)

Article Biochemistry & Molecular Biology

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

Takuya Sekine et al.

Letter Medicine, General & Internal

Rapid Decay of Anti-SARS-CoV-2 Antibodies in Persons with Mild Covid-19

F. Javier Ibarrondo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Editorial Material Medicine, General & Internal

Global perspective of COVID-19 epidemiology for a full-cycle pandemic

John P. A. Ioannidis

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Medicine, General & Internal

Emergence of coronavirus disease 2019 (COVID-19) in Austria

Peter Kreidl et al.

WIENER KLINISCHE WOCHENSCHRIFT (2020)

Article Immunology

Prevalence of SARS-CoV-2 infection in India: Findings from the national serosurvey, May-June 2020

Manoj V. Murhekar et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2020)